Ahmad Aamir Breast Cancer Metastasis and Drug Resistance: Challenges and Progress 9783030203009

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Автор: Ahmad Aamir
Название: Breast Cancer Metastasis and Drug Resistance: Challenges and Progress
ISBN: 9783030203009
Издательство: Springer
Классификация:

Исследования средств массовой информации

Онкология

Фармакология

ISBN-10: 303020300X
Обложка/Формат: Hardcover
Страницы: 427
Вес: 0.80 кг.
Дата издания: 05.09.2019
Серия: Advances in experimental medicine and biology
Язык: English
Издание: 2nd ed. 2019
Иллюстрации: 51 illustrations, color; 9 illustrations, black and white; xviii, 427 p. 60 illus., 51 illus. in color.
Размер: 253 x 253 x 27
Читательская аудитория: Professional & vocational
Подзаголовок: Challenges and progress
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Дополнительное описание:

Chaper 1: Breast Cancer Statistics: Recent trends.- Chapter 2: Epidemiology of Breast Cancer in Women.- Chapter 3: Health and Racial Disparity in Breast Cancer.- Chapter 4: Breast Cancer: Current perspectives on the disease status.- Chapter 5: Role o

Breast Cancer Metastasis and Drug Resistance: Challenges and Progress, Ahmad Aamir