Atlas of Interstitial Lung Disease Pathology, Andrew Churg, Nestor L. Muller
Старое издание
Автор: Talbot, Ian Название: Biopsy Pathology in Colorectal Disease, 2Ed ISBN: 0340759224 ISBN-13(EAN): 9780340759226 Издательство: Taylor&Francis Рейтинг: Цена: 32155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A thorough guide to the diagnosis of colorectal conditions, both common and rare, providing expert guidance in the handling of biopsy specimens.
Автор: Heymer Berno Название: Clinical and Diagnostic Pathology of Graft-versus-Host Disease ISBN: 3642087213 ISBN-13(EAN): 9783642087219 Издательство: Springer Рейтинг: Цена: 8804.00 р. 12577.00-30% Наличие на складе: Есть (2 шт.) Описание: While comprehensive descriptions of the various aspects of Graft-versus-Host Disease (GvHD) have already been published, to date there is no monograph on the clinical and diagnostic pathology of this life-threatening disease. This book fills this gap and serves as a reliable guide to the histomorphologic diagnosis of GvHD.
Автор: Mayhan William G. Название: Blood-Brain Barrier in Health and Disease ISBN: 1615047395 ISBN-13(EAN): 9781615047390 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 5016.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. The structure of this endothelial barrier is unique among endothelia of other organ systems and is composed of complexes made up of tight, gap and adherens junctions. In addition, it is the responsibility of the surrounding cellular elements to maintain the integrity of the junctional complexes and restrict the entry of substances from the blood into the brain. Changes in permeability of the BBB during physiologic and pathophysiologic conditions involve alterations in specific transporters at the level of the endothelium, activation of specific cellular second messenger pathways and/or the dissolution of the junctional complexes composing the BBB. This book focuses on various aspects that account for the formation and maintenance of the BBB, and on disease states that compromise this barrier.
Автор: Shaw Watanabe; Marianne Wolff; Sheldon C. Sommers Название: Digestive Disease Pathology ISBN: 3662115646 ISBN-13(EAN): 9783662115640 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Each chapter contains numerous electron micrographs, often supplemented byline drawings, and extensive references to the literature.The clear illustrations and text are an excellent aid for the diagnosis of pathological entities in the gastrointestinal tract.
Автор: Mitchell, Maika Название: Molecular Pathology and the Dynamics of Disease ISBN: 0128146109 ISBN-13(EAN): 9780128146101 Издательство: Elsevier Science Рейтинг: Цена: 12961.00 р. Наличие на складе: Поставка под заказ.
Описание:
Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective.
Assimilates theoretical knowledge with practical lab work
Provides a needed clinical perspective, along with research and theory
Highlights the impact of basic science on the practice of medicine
Автор: Kradin, Richard L. Название: Diagnostic Pathology of Infectious Disease, 2nd Edition ISBN: 0323445853 ISBN-13(EAN): 9780323445856 Издательство: Elsevier Science Рейтинг: Цена: 32000.00 р. Наличие на складе: Поставка под заказ.
Описание:
Comprehensive and up to date, the Second Edition of Diagnostic Pathology: Infectious Disease, by Dr. Richard Kradin, is an invaluable tool for the accurate diagnosis of any infectious disease?from the common to the most challenging. The organ-based format makes it an especially useful tool for surgical pathologists' daily diagnostic and management issues. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion, clearly depicting how to recognize the morphology of organisms and the spectrum of histological responses that they may cause.
Addresses the most difficult diagnostic issues
that practicing or trainee surgical pathologists face when handling infectious disease tissue specimens.
Highlights morphological characteristics and landmarks of tissue samples for easy access to information necessary for signing out a specimen.
Emphasizes the host responses critical in differential diagnosis to serve as a second opinion when non-infectious diagnoses mimic and confound the diagnosis of infection.
Completely revised
with the latest diagnostic support and hot topics in the field:
A new chapter on novel techniques in microbiology
A new chapter on eye infections
New coverage of immunohistochemical staining and other molecular diagnostic techniques
New discussions of human papillomavirus, a critical tool in predictive cancer screening
New information on infections in the immunocompromised host and related special considerations
Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.
Описание: Provides the practicing pathologist with the tools necessary to synthesize diagnoses in biopsy and surgical specimens of non-neoplastic lung disease. In this heavily illustrated and concisely written book, Dr. Katzenstein has brought a pattern-based approach to formulating diagnoses in non-neoplastic lung diseases with the non-expert pulmonary pathologist in mind.
Автор: Bryan H. Schmitt Название: Atlas of Infectious Disease Pathology ISBN: 3319547011 ISBN-13(EAN): 9783319547015 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Infectious diseases may be encountered in nearly every aspect of pathology. The Atlas of Infectious Disease Pathology is organized primarily by pathogen type followed by discussion of the various manifestations that may occur in individual organ systems.
Описание: Uniquely addresses the long overdue need for an authoritative, immersive approach to paediatric cardiac pathology. For general and paediatric pathologists, this book covers all aspects of diseases and malformations of the heart. Extensively illustrated, it approaches work from the fetus to the adolescent, including the effects of surgery.
Автор: Messing Albee Название: Alexander Disease: A Guide for Patients and Families ISBN: 1615047581 ISBN-13(EAN): 9781615047581 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3756.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book offers a comprehensive overview of Alexander disease, a rare and devastating neurological disorder that often affects the white matter of the brain and spinal cord.
Its distinctive neuropathology consists of abundant Rosenthal fibers within astrocytes (one of the four major cell types of the central nervous system). Nearly all cases are caused by variants in the gene encoding the intermediate filament protein GFAP, but how these changes in GFAP lead to the widespread manifestations of disease is poorly understood.
Astrocytes, while discovered over a century ago, are themselves still much of a mystery. They exhibit considerable diversity, defy precise definition, and yet actively regulate many aspects of nervous system functioning.
We also have incomplete understanding of Rosenthal fibers, odd structures that contain GFAP as just one of many components. Whether they are toxic or protective is unknown. Moreover, Rosenthal fibers are not absolutely unique to Alexander disease, and are seen sporadically in a wide variety of other conditions, including brain tumors and multiple sclerosis.
GFAP is the third unknown. It is an ancient protein, arising early in the evolution of vertebrates, but its role in normal biology is still a matter of debate. Yet Alexander disease shows, without a doubt, that changing just a single of its 432 amino acids can lead to catastrophe, not just in the astrocytes where GFAP is produced but also in the other cells with which astrocytes interact.
Despite all of the unknowns, much has been learned in the past 20 years, and it is time to share this knowledge. This book is intended for recently diagnosed patients and families, as well as non-specialist researchers interested in this neurological disease. It covers historical origins, the state of current knowledge, and prospects for what lies ahead, with citations to the primary literature given throughout.
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