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Phytochemicals as lead compounds for new drug discovery, 


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Цена: 29476.00р.
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Название:  Phytochemicals as lead compounds for new drug discovery
ISBN: 9780128178904
Издательство: Elsevier Science
Классификация:
ISBN-10: 0128178906
Обложка/Формат: Paperback
Страницы: 378
Вес: 1.05 кг.
Дата издания: 10.09.2019
Язык: English
Размер: 216 x 279 x 26
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases.

Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain.

  • Presents fundamental concepts and factors affecting choice for plant-based products
  • Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward
  • Highlights recent advances in computational-based drug discovery
  • Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance



Himalayan Phytochemicals

Автор: Jan, Sumira
Название: Himalayan Phytochemicals
ISBN: 0081022271 ISBN-13(EAN): 9780081022276
Издательство: Elsevier Science
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Цена: 30318.00 р.
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Описание: Himalayan Phytochemicals: Sustainable Options for Sourcing and Developing Bioactive Compounds provides a detailed review of the important medicinal plants which have already been discovered in the Himalayan region, outlining their discovery, activity and underlying chemistry. In addition, it supports a global shift towards sustainable sourcing of natural products from delicate ecosystems. Across the world, environmental destruction and overharvesting of medicinal plants are reducing and destroying multiple important sources and potential leads before researchers have the chance to discover, explore or synthesize them effectively. By identifying this problem and discussing its impact on the Himalayan region, Himalayan Phytochemicals: Sustainable Options for Sourcing and Developing Bioactive Compounds frames the ongoing global struggle and highlights thekey factorsthat must be considered and addressed when working with phytochemicals from endemic plant sources.

Mechanism of the Anticancer Effect of Phytochemicals

Автор: Bathaie S.
Название: Mechanism of the Anticancer Effect of Phytochemicals
ISBN: 0128038764 ISBN-13(EAN): 9780128038765
Издательство: Elsevier Science
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Цена: 18528.00 р.
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Описание: Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of The Enzyme series was on Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals.

Natural Products Pharmacology and Phytochemicals for Health Care

Название: Natural Products Pharmacology and Phytochemicals for Health Care
ISBN: 1771889012 ISBN-13(EAN): 9781771889018
Издательство: Taylor&Francis
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Цена: 21284.00 р.
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Описание: The book looks into the research, discovery and characterization of the chemicals that exhibit biological effects. Providing an informative compilation of research, valuable case studies, and review of existing literature in the area, the book focuses on the ethnobotanical uses of natural products and phytochemicals for health care.

Antifungal Compounds Discovery

Автор: Sokovic, Marina
Название: Antifungal Compounds Discovery
ISBN: 0128158247 ISBN-13(EAN): 9780128158241
Издательство: Elsevier Science
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Цена: 23749.00 р.
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Описание:

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compound Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections.

Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field.

Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compound Discovery is a comprehensive guide helping researchers understand the relationship between specific chemicals structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds.


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