Plant flavonoids affect cancer chemotherapeutic efficacy: a handbook for doctors and patients,
Автор: Swanson Hollie Название: Flavonoids, Inflammation and Cancer ISBN: 9814651931 ISBN-13(EAN): 9789814651936 Издательство: World Scientific Publishing Цена: 13464.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an insightful analysis of the chemopreventive actions of flavonoids.
Автор: Katrin Sak Название: Dietary Flavonoids Interfere with Cancer Radiotherapy ISBN: 1536167800 ISBN-13(EAN): 9781536167801 Издательство: Nova Science Рейтинг: Цена: 11562.00 р. Наличие на складе: Невозможна поставка.
Описание: In parallel with the continuous rise of cancer incidence, efficient treatment becomes an increasingly important public health concern. Radiotherapy has remained one of the most important anticancer approaches for clinical management of a variety of human tumors, as at least half of all oncological patients receive this therapy at some stages of their disease. With the hope to attain greater anticancer response, the interest in using natural plant-derived products as complementary treatments to conventional radiotherapy has substantially increased in the recent years. However, the interactions between phytochemicals and ionizing radiation are not always known and can be often unpredictable. Therefore, in this book, the current findings about the combined treatments of malignant cells with radiation and flavonoids, the largest group of human dietary plant polyphenols, are described. These data show that under carefully chosen dosage-schedule regimens, certain flavonoids or their natural mixtures can behave as potent radiosensitizers, augmenting radiotherapeutic efficacy in different preclinical cancer models. Such radiosensitizing action of flavonoids can be achieved through modulation of the redox status and suppression of several cellular survival pathways activated by radiotherapy, ultimately leading to the death of malignant cells. As flavonoids can concurrently protect normal healthy cells from irradiation-induced injury and thereby minimize toxic adverse reactions, use of these plant-derived agents as complementary approach to radiotherapy might open new avenues for enhancement of clinical outcome. Therefore, combining conventional anticancer modalities with conscious intake of flavonoid supplements as adjuvant agents might be an important future strategy to boost the therapeutic success in the treatment of various human malignancies.
Автор: Frank M. Torti Название: Urologic Cancer: Chemotherapeutic Principles and Management ISBN: 3642819966 ISBN-13(EAN): 9783642819964 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: M.R. Sather Название: Cancer Chemotherapeutic Agents ISBN: 9024721709 ISBN-13(EAN): 9789024721702 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book comprehensively introduces readers to various aspects of flavonoids, a category of natural metabolites that exhibits various pharmacological effects. It discusses their chemistry, absorption and metabolism, mechanisms of action and toxicology as well as future perspectives for clinical applications, and also provides detailed insights into their anti-cancer properties, since flavonoids are known to modulate tumor-associated intracellular as well as extracellular signaling pathways. The book also highlights the current research on the health effects of selected flavonoids, and their various roles in cancer prevention and treatment. Lastly, the book elucidates nanotechnology-mediated tools to enhance the bioavailability and solubility of flavonoids to improve their bioactivity and pharmacokinetic parameters.
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