This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Описание: Reflecting the significant developments of the past decade, this textbook explains key physical methods in modern biology. Each method is illustrated through real-world examples, alongside background information designed for both physicists and biologists, making this an ideal resource for students in biophysics at science and medical schools.
Автор: Haines Duane E. Название: Fundamental Neuroscience for Basic and Clinical Applications ISBN: 0323396321 ISBN-13(EAN): 9780323396325 Издательство: Elsevier Science Рейтинг: Цена: 12968.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Using a rigorous yet clinically-focused approach, Fundamental Neuroscience for Basic and Clinical Applications, 5th Edition, covers the fundamental neuroscience information needed for coursework, exams, and beyond. It integrates neuroanatomy, pharmacology, and physiology, and offers a full section devoted to systems neurobiology, helping you comprehend and retain the complex material you need to know.
Highlights clinical content in blue
throughout the text, helping you focus on what you need to know in the clinical environment.
Presents thoroughly updated information in every chapter, with an emphasis on new clinical thinking as related to the brain and systems neurobiology.
Features hundreds of correlated state-of-the-art imaging examples, anatomical diagrams, and histology photos - nearly half are new or improved for this edition.
Pays special attention to the correct use of clinical and anatomical terminology, and provides new clinical text and clinical-anatomical correlations.
Автор: Hamid Reza Rezaie; Leila Bakhtiari; Andreas ?chsne Название: A Review of Biomaterials and their Applications in Drug Delivery ISBN: 9811005028 ISBN-13(EAN): 9789811005022 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews drug delivery systems as mechanisms to introduce therapeutic agents into the body to help or improve tissue function, and examines different drug delivery systems applied in various organs.
Описание: This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs).
Автор: Jin Chen; Ling Chen; Fengwei Xie; Xiaoxi Li Название: Drug Delivery Applications of Starch Biopolymer Derivatives ISBN: 9811336563 ISBN-13(EAN): 9789811336560 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the recent advances in applications of starch in state-of-the-art drug carriers (hydrogel, micro- and nano-particulate carriers) with stimulus-responsive and target-specific properties. It also highlights the role of starch and its derivatives in transmucosal administration to improve the bioavailability of drugs. Further, it outlines the principles of effective, advanced, starch-based drug delivery systems and illustrates how these principles are key to the development of future drug delivery strategies. This interesting reference resource is useful for students, researchers and engineers in the fields of carbohydrate chemistry, polymer sciences and drug delivery.
Описание: This book contains the full papers presented at the MICCAI 2014 workshop on Computational Methods and Clinical Applications for Spine Imaging. The workshop brought together scientists and clinicians in the field of computational spine imaging. The chapters included in this book present and discuss the new advances and challenges in these fields, using several methods and techniques in order to address more efficiently different and timely applications involving signal and image acquisition, image processing and analysis, image segmentation, image registration and fusion, computer simulation, image based modeling, simulation and surgical planning, image guided robot assisted surgical and image based diagnosis.
The book also includes papers and reports from the first challenge on vertebra segmentation held at the workshop.
Описание: This book intends to provide an up-to-date information in the field of nanobiomedicine. The focus of the book is on the basic concepts and recent developments in the field of nanotechnology.
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