Understanding halogenation 9781536159479

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Название: Understanding halogenation
ISBN: 9781536159479
Издательство: Nova Science
Классификация:

ISBN-10: 1536159476
Обложка/Формат: Paperback
Страницы: 118
Вес: 0.19 кг.
Дата издания: 10.10.2019
Серия: Chemistry
Язык: English
Размер: 154 x 230 x 9
Читательская аудитория: Professional & vocational
Ключевые слова: Organic chemistry
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Поставляется из: Англии
Описание: Parkinsons disease is the second most prevalent aging-related neurodegenerative disorder. Cell death in the substantia nigra, a motor region of the nervous system, is the key factor for the emergence of motor deficits in patients, although its critical role in Parkinsons disease pathogenesis is put into question. This book explores how halogenation stress could participate in neuronal damage of the nervous system and parkinsonian deficits. Following this, new insights into the C-F bonding nature of graphite fluorides with different fluorine concentrations C4F, C2F and C1F are presented. They are based on recent data from bulk techniques, which are very sensitive to the atomic local and electronic structure and C hybridisation such as X-ray Raman Scattering and Pair Distribution Function analysis. Lastly, a novel bromine-containing Still -- Gennari-type phosphonate reagent, methyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)-2-bromoacetate is designed, synthesised, and applied to the stereoselective construction of trisubstituted alkenes via bromomethylenation of carbonyl groups.

Understanding halogenation,