Tuberculosis in Animals: An African Perspective, Dibaba
Автор: Jeffrey D. Cirillo; Ying Kong Название: Tuberculosis Host-Pathogen Interactions ISBN: 3030253805 ISBN-13(EAN): 9783030253806 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the progress in studies of tuberculosis host-pathogen interactions from several perspectives: molecular microbiology, immunology, animal models, clinical studies, epidemiology, and drug discovery. Tuberculosis (TB) remains a severe global public health problem. Complex interactions between environmental, microbial and host factors lead to clinically relevant infections. Studies on bacterial virulence, host-genetic, and immunological factors contributing to the susceptibility to TB provide an ever-growing foundation of knowledge that is critical to finding new interventions. Studies of immune mechanisms against M. tuberculosis infection have identified immunological markers associated with specific phenotypes in the host, providing insight into how they may be used to augment current treatment strategies. Recent advances in diagnosis, therapeutics and vaccines, as well as basic-research oriented studies have shed light on the development of new directions for prevention, treatment and control of TB. Improved understanding of the interplay between the bacterium and host is a key component of reducing incidence worldwide.
First published in 1979, Why Big Fierce Animals Are Rare has established itself as a seminal work in ecology. Now with a new foreword by ecologist and writer Cristina Eisenberg, this penetrating study of ecosystems and animal populations is more relevant than ever. What accounts for the many different species of insect? Why does the robin population stay relatively steady year after year, despite the fact that their nests contain several chicks at once? Paul Colinvaux traces the ecologist's quest to answer these questions and more in this accessibly written book. He brings to the subject both profound knowledge and an enthusiasm that will encourage a greater understanding of the environment and of the efforts of those who seek to preserve it.
Автор: Sereti Название: HIV and Tuberculosis ISBN: 3030291073 ISBN-13(EAN): 9783030291075 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities. The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike.
Автор: Yichen Lu; Lixia Wang; Hongjin Duanmu; Chris Chany Название: Handbook of Global Tuberculosis Control ISBN: 1493982664 ISBN-13(EAN): 9781493982660 Издательство: Springer Рейтинг: Цена: 39130.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This ambitious reference surveys worldwide efforts at controlling the spread of tuberculosis, with special emphasis on the developing world. Case studies from China, Pakistan, Nigeria, Indonesia, and other frontline countries demonstrate a wealth of information on clinical, cultural, socioeconomic, and other relevant factors. This compilation provides a valuable resource for creating successful intervention and prevention strategies. State-of-the-science snapshots pinpoint where short- and long-term initiatives stand today, from early detection and vaccination programs to new genetic technologies and drug therapies. This diverse group of perspectives and approaches offers innovative paths toward control and realistic odds for containing the threat, especially in the face of current co-epidemics and new drug-resistant strains. Among the topics in the Handbook: * Diagnosis of tuberculosis: current pipeline, unmet needs, and new developments * Concurrence of tuberculosis and other major diseases * The tuberculosis outbreak response, investigation, and control * The promise of new TB vaccines * DNA fingerprinting of Mycobacterium tuberculosis: a rich source of fundamental and daily applicable knowledge * Global tuberculosis surveillance The Handbook of Global Tuberculosis Control is urgent reading for leadership and staff of non-governmental organizations, government agencies, academic institutions, research centers, hospitals, and potentially businesses with interests in tuberculosis control. Additionally, the book's focus on TB in developing countries will attract a wider audience of practitioners, particularly those working in the broader fields of global public health, epidemiology, international development, and the socioeconomics of infectious diseases.
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