Drug Resistance in Leishmania Parasites, Ponte-Sucre
Автор: Andr? L.S. Santos; Marta H. Branquinha; Claudia M. Название: Proteins and Proteomics of Leishmania and Trypanosoma ISBN: 9400773048 ISBN-13(EAN): 9789400773042 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Awanish Kumar Название: Leishmania and Leishmaniasis ISBN: 1461488680 ISBN-13(EAN): 9781461488682 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Drug Discovery for Leishmaniasis ISBN: 1782628894 ISBN-13(EAN): 9781782628897 Издательство: Royal Society of Chemistry Рейтинг: Цена: 31469.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania.
Автор: Bruschi Название: The Leishmaniases: Old Neglected Tropical Diseases ISBN: 3319891790 ISBN-13(EAN): 9783319891798 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Поставка под заказ.
Описание: Out of the 20 neglected tropical diseases (NTDs) prioritized by the World Health Organization, the leishmaniases rank in the top 3 among those caused by protozoa. The purpose of this book is to provide the reader with a comprehensive and updated overview of all the aspects of leishmaniasis with a worldwide perspective – authors of many chapters include eminent scientists from both the Old and New Worlds. The chapters cover a wide range of topics, classically organized into biology and epidemiology, followed by clinical and control aspects. Following an introductory chapter intended to take the reader into the leishmaniasis complexity, a chapter on Leishmania taxonomy reports on the most recent advances in molecular and phylogenetic data. Parasite biology is then described in detail by means of two separate chapters devoted to phlebotomine vectors and reservoir hosts, respectively. The medical part of the book begins with a chapter on basic immunology and immunopathology associated with Leishmania infection, followed by a classical chapter on clinical aspects of different disease entities. The complexity of disease case management is presented by means of 3 chapters, respectively on diagnosis, treatment of visceral forms and treatment of tegumentary forms. Finally, the last chapter deals with the available approaches to control leishmaniasis and related public health issues.
Автор: Clos Название: Leishmania ISBN: 1493992090 ISBN-13(EAN): 9781493992096 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface...Table of Contents...Contributing Authors... 1. Host-Free Systems for Differentiation of Axenic LeishmaniaDan Zilberstein and Roni Nitzan Koren 2. Phylogenetic StudiesKatrin Kuhls and Isabel Mauricio 3. A Guide to Next Generation Sequence Analysis of Leishmania GenomesHideo Imamura and Jean-Claude Dujardin 4. Quantitative RNA Analysis using RNA SeqPeter J. Myler, Jacqueline A. McDonald, Pedro Alcolea, and Aakash Sur 5. Ribosome Profiling in TrypanosomatidsAmelie J. Kraus and Raъl O. Cosentino 6. Cosmid Library Construction and Functional CloningJoachim Clos and Dorotheo Zander-Dinse 7. Cos-Seq, A High Throughput Gain of Function Screen for Drug Resistance Studies in LeishmaniaJade-Eva Potvin, Philippe Leprohon, Elodie Gazanion, Mansi Sharma, Christopher Fernandez-Prada, and Marc Ouellette 8. Gene Replacement by Homologous RecombinationHenner Zirpel and Joachim Clos 9. LeishGEdit: A Method for Rapid Gene Knockout and Tagging using CRISPR-Cas9Tom Beneke and Eva Gluenz 10. DiCre-Based Inducible Disruption of Leishmania GenesSamuel M. Duncan, Elmarie Myburgh, Eliza Alves-Ferreira, and Jeremy C. Mottram 11. DiCre-Based Inducible Gene ExpressionJeziel D. Damasceno, Luiz R. O. Tosi, Renato E. R. S. Santos, and Jeremy C. Mottram 12. Generation of Bone Marrow-Derived Macrophages for In Vitro Infection ExperimentsEugenia Bifeld 13. Quantification of Intracellular Leishmania spp. Using Real-Time Quantitative PCR (qPCR)Eugenia Bifeld 14. In Vitro Infections of Macrophage-Like Cell Lines with Leishmania infantum for Drug ScreeningNuno Santarйm, Joana Tavares, and Anabela Cordeiro-da-Silva 15. Quantification of Parasite Loads by Automated Microscopic Image AnalysisCarolina Borsoi Moraes and Laura Maria Alcвntara 16. Quantification of Leishmania Parasites in Murine Models of Visceral InfectionJoana Tavares, Nuno Santarйm, and Anabela Cordeiro-da-Silva 17. Syrian Hamster as an Advanced Experimental Model for Visceral LeishmaniasisMarнa Dolores Jimйnez-Antуn, Montserrat Grau, Ana Isabel Olнas-Molero, and Josй Ma Alunda 18. Experimental Cutaneous Leishmaniasis: Mouse Models for Resolution of Inflammation versus Chronicity of DiseaseChristian Bogdan, Andrea Debus, Heidi Sebald, Bapli Rai, Johanna Schдfer, Stephanie Obermeyer, and Ulrike Schleicher 19. Establishment, Maintenance of Phlemotomus spp. In the Laboratory, and Infection with Leishmania spp.Ifhem Chelbi and Elyes Zhioua
Автор: Jay P. Farrell Название: Leishmania ISBN: 146135322X ISBN-13(EAN): 9781461353225 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Andr? L.S. Santos; Marta H. Branquinha; Claudia M. Название: Proteins and Proteomics of Leishmania and Trypanosoma ISBN: 9402407499 ISBN-13(EAN): 9789402407495 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface.- Biology of Human Pathogenic Trypanosomatids: Epidemiology, Lifecycle and Ultrastructure.- Selection of Molecular Targets for Drug Development against Trypanosomatids.- A2 and other visceralizing proteins of Leishmania: role in pathogenesis and application for vaccine development.- Arginase in Leishmania.- The heat shock proteins of Trypanosoma cruzi.- The Gp82 Surface Molecule of Trypanosoma cruzi Metacyclic Forms.- The Gp85 Surface Glycoproteins from Trypanosoma cruzi.- Trypanosoma cruzi Trans-Sialidase: Structural Features and Biological Implications.- Surface Topology Evolution of Trypanosoma Trans-Sialidase.- Ecto-Nucleotidases and Ecto-Phosphatases from Leishmania and Trypanosoma Parasites.- Gp63 Function in the Interaction of Trypanosomatids with the Invertebrate Host - Facts and Prospects.- Highlights on Trypanosomatid Aminoacyl-tRNA Synthesis.- The Expected Outcome of the Trypanosoma cruzi Proteomic Map: a Review of its Potential Biological Applications for Drug Target Discovery.- Proteomics advances in the study of Leishmania parasites and leishmaniasis.- Towards the Phosphoproteome of Trypanosomatids. Index.
Автор: Satoskar Abhay Название: Pathogenesis of Leishmaniasis ISBN: 146149107X ISBN-13(EAN): 9781461491071 Издательство: Springer Рейтинг: Цена: 19591.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details the latest research into leishmaniasis. It also addresses how advances in understanding can be applied to prevention, control and treatment of what the WHO has classified a neglected tropical disease.
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