Автор: Songtao Qi Название: Atlas of Craniopharyngioma ISBN: 9811373248 ISBN-13(EAN): 9789811373244 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Нет в наличии.
Описание: This book aims to facilitate readers to understand the origin, growth pattern and relationship between tumor and adherent structure of craniopharyngioma, so as to improve the cure rate and safety of surgery.
Автор: Juan Pedro Martinez-Barbera; Cynthia Lilian Andoni Название: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma ISBN: 3319847708 ISBN-13(EAN): 9783319847702 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and vascular structures. These tumors, as well as the current treatments, may result in pan-hypopituitarism, diabetes insipidus, morbid obesity followed by type II diabetes mellitus, blindness, as well as serious behavioral and psychosocial impairments. Exploring in detail advances in both the understanding of tumor biology as well as clinical advances in patient management are explored in detail, this book will also look towards potential new treatment approaches.
Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma is the first book compiling all current research on ACPs. Mouse and human studies have unequivocally demonstrated that mutations in CTNNB1 encoding -catenin underlie the etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In addition, a role for tissue-specific adult pituitary stem cells has been revealed as causative of ACP. Together, these studies have provided novel insights into the molecular and cellular etiology as well as the pathogenesis of human ACP. Finally, this volume covers new treatment approaches that have been shown to be effective both in reducing ACP burden as well as reducing the morbidity associated with therapy.
Автор: Qi Название: Atlas of Craniopharyngioma ISBN: 9811373213 ISBN-13(EAN): 9789811373213 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Нет в наличии.
Описание: This book aims to facilitate readers to understand the origin, growth pattern and relationship between tumor and adherent structure of craniopharyngioma, so as to improve the cure rate and safety of surgery.
Автор: Giovanni Broggi Название: Craniopharyngioma ISBN: 3540750010 ISBN-13(EAN): 9783540750017 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Describing the various therapeutic strategies used to combat this benign tumour, this study suggests multimodal treatment approaches, including microsurgery and stereotaxis. The rationale for each therapeutic choice is supported by biological, clinical and neuroradiological data.
Автор: Juan Pedro Martinez-Barbera; Cynthia Lilian Andoni Название: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma ISBN: 3319518887 ISBN-13(EAN): 9783319518886 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Pathogenesis of human ACP.- Transcriptomic and Genomic Analyses of Human Craniopharyngioma.- Genetically Modified Mouse Models of Adamantinomatous Craniopharyngioma.- Clinical Diagnosis of Human ACP.- Endocrine Deficits in Patients with Human Craniopharyngioma.- Obesity and metabolic disturbances in Adamantinomatous Craniopharyngioma Patients.- Radiology and Radiotherapy of Craniopharyngioma.- Surgical Treatment of Human ACP.- Intracystic Administration of Interferon-Alpha for Reduction of Cystic Tumour Burden.- Long-term Management and Clinical Trials in Adamantinomatous Craniopharyngioma
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