Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commercialization of transdermal drug delivery requires technology from many disciplines beyond pharmaceutical sciences, such as polymer chemistry, adhesion sciences, mass transport, web film coating, printing, and medical technology.
A comprehensive discussion of these technologies and practices, Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies covers:
Commercial development of devices and products based on transdermal physical enhancement technologies
Selecting optimal enhancement technology for a specific drug molecule using case studies
Physicochemical properties and practical commercial considerations related to cost, unmet clinical needs, marketing, or intellectual property protection
Technologies such as microneedles, iontophoresis, electroporation, and sonophoresis, with examples for delivery of small molecules, cosmeceuticals, proteins, and vaccines
Practical information on experimental procedures and challenges related to skin irritation and safety issues
Up-to-date and accessible to researchers and industry experts, this book provides a comprehensive discussion of the physical approaches and practical considerations for the laboratory and marketplace.
Автор: Keservani Raj K., Sharma Anil K., Kesharwani Rajesh Kumar Название: Novel Approaches for Drug Delivery ISBN: 1522507515 ISBN-13(EAN): 9781522507512 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 26334.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Providing optimal care to patients is a primary concern in the healthcare field. By utilizing the latest resources and research in biomedical applications, the needs and expectations of patients can be successfully exceeded. Novel Approaches for Drug Delivery is an authoritative reference source for the latest scholarly research on emerging developments within the pharmaceutical industry, examining the current state and future directions of drug delivery systems. Highlighting therapeutic applications, predictive toxicology, and risk assessment perspectives, this book is ideally designed for medical practitioners, pharmacists, graduate-level students, scientists, and researchers.
Автор: S.P. Vyas, Roop V. Khar, Sonal Vyas Название: Introduction of Novel Drug Delivery Systems ISBN: 938852781X ISBN-13(EAN): 9789388527811 Издательство: CBS India Рейтинг: Цена: 6270.00 р. Наличие на складе: Нет в наличии.
Описание: This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation,thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles,resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.
Описание: By endowing drugs with new and innovative therapeutic benefits, drug delivery systems extend products` profitable lifecycle, giving pharmaceutical companies competitive and financial advantages, and providing patients with improved medications.
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