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Prefoldins: the new chaperones, Nabil Djouder


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Автор: Nabil Djouder
Название:  Prefoldins: the new chaperones
ISBN: 9783030007362
Издательство: Springer
Классификация:







ISBN-10: 3030007367
Обложка/Формат: Hardcover
Страницы: 135
Вес: 0.63 кг.
Дата издания: 2018
Серия: Advances in Experimental Medicine and Biology
Язык: English
Издание: 1st ed. 2018
Иллюстрации: 37 tables, color; 36 illustrations, color; 3 illustrations, black and white; ix, 135 p. 39 illus., 36 illus. in color.
Размер: 259 x 231 x 13
Читательская аудитория: Professional & vocational
Ключевые слова: Human Genetics
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease. This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined.This work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.
Дополнительное описание: Preface.- Structure of the molecular chaperone prefoldin.- Structure and function of archaeal prefoldin.- Role and functions of prefoldins.- Nuclear functions of prefoldins.- The yeast prefoldin Bud27.- URI-like prefoldin complex.- HSP90 and its R2TP/Pref



Molecular Chaperones

Автор: Stuart K. Calderwood; Thomas L. Prince
Название: Molecular Chaperones
ISBN: 1493961705 ISBN-13(EAN): 9781493961702
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Chaperones

Автор: Stuart K. Calderwood; Thomas L. Prince
Название: Chaperones
ISBN: 1493974769 ISBN-13(EAN): 9781493974764
Издательство: Springer
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Цена: 23757.00 р.
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Описание:

This volume is a compilation of laboratory protocols and methodology required for the study of molecular chaperones and the cellular stress response. Chapters detail stress response in Hsf1, Hsf2 and Hsf4 knockout mice, mapping HSP interaction networks, the LUminescence-based Mammalian IntERactome (LUMIER), Hsp70 biology, protein folding activity of Hsp90, cytotoxicity of HSP inhibitors, computational approaches for modeling allosteric Hsp90 interactions, HSPs in immunity and vaccine development, and biologies of Hsp70 and Hsp90. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Chaperones: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Networking of chaperones by co-chaperones

Название: Networking of chaperones by co-chaperones
ISBN: 3319117300 ISBN-13(EAN): 9783319117300
Издательство: Springer
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Цена: 25155.00 р.
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Описание: Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

RNA Chaperones

Автор: Tilman Heise
Название: RNA Chaperones
ISBN: 1071602306 ISBN-13(EAN): 9781071602300
Издательство: Springer
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Цена: 18167.00 р.
Наличие на складе: Поставка под заказ.

Описание: This book provides a wide spectrum of methods to study RNA chaperones in vitro, at the single molecule level, and protocols useful for cell-based assays. Beginning with a section on a number of bacterial proteins for study, the volume also explores proteins from eukaryotic cells and how to delve into the complex interactions between RNA chaperones and the folding and unfolding of proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Chaperones: Methods and Protocols serves as an ideal guide for scientists and students interested in RNA biology and RNA chaperones. Chapter 3 is available Open Access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Chaperones

Автор: Stuart K. Calderwood; Thomas L. Prince
Название: Chaperones
ISBN: 1493984985 ISBN-13(EAN): 9781493984985
Издательство: Springer
Рейтинг:
Цена: 16769.00 р.
Наличие на складе: Поставка под заказ.

Описание: This volume is a compilation of laboratory protocols and methodology required for the study of molecular chaperones and the cellular stress response.  Chapters detail stress response in Hsf1, Hsf2 and Hsf4 knockout mice, mapping HSP interaction networks, the LUminescence-based Mammalian IntERactome (LUMIER), Hsp70 biology, protein folding activity of Hsp90, cytotoxicity of HSP inhibitors, computational approaches for modeling allosteric Hsp90 interactions, HSPs in immunity and vaccine development , and biologies of Hsp70 and Hsp90. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Chaperones: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks

Автор: Peter Csermely; L?szl? V?gh
Название: Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks
ISBN: 1441922970 ISBN-13(EAN): 9781441922977
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.

The Networking of Chaperones by Co-chaperones

Автор: Gregory Lloyd Blatch; Adrienne Lesley Edkins
Название: The Networking of Chaperones by Co-chaperones
ISBN: 3319381490 ISBN-13(EAN): 9783319381497
Издательство: Springer
Рейтинг:
Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

Inhibitors of Molecular Chaperones as Therapeutic Agents

Название: Inhibitors of Molecular Chaperones as Therapeutic Agents
ISBN: 1849736669 ISBN-13(EAN): 9781849736664
Издательство: Royal Society of Chemistry
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Цена: 33790.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research.

The Networking of Chaperones by Co-chaperones

Автор: Gregory L. Blatch
Название: The Networking of Chaperones by Co-chaperones
ISBN: 1441923780 ISBN-13(EAN): 9781441923783
Издательство: Springer
Рейтинг:
Цена: 27951.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The Networking of Chaperones by Co-chaperones updates the current understanding of how chaperones are regulated and networked. It is a resource for those in the specialized field of cell stress and chaperones. The book will also be of interest to those in broader cross-cutting field such as cellular networks and systems biology.


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