Irena Roterman; Leszek Konieczny Self-Assembled Molecules – New Kind of Protein Ligands 9783319880716

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Автор: Irena Roterman; Leszek Konieczny
Название: Self-Assembled Molecules – New Kind of Protein Ligands
ISBN: 9783319880716
Издательство: Springer
Классификация:

Медицинское оборудования и методики его эксплуатации

Медицинские исследования

Биология и науки о жизни

Биохимия

Белки

Базы данных

ISBN-10: 3319880713
Обложка/Формат: Soft cover
Страницы: 136
Вес: 0.33 кг.
Дата издания: 2018
Язык: English
Издание: Softcover reprint of
Иллюстрации: 44 illustrations, color; 54 illustrations, black and white; xii, 136 p. 98 illus., 44 illus. in color.
Размер: Book (Paperback Initiative)
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Supramolecular Ligands
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. This book is an open access under a CC BY license.

Дополнительное описание:

Supramolecular Protein Ligands – Unexplored Teritory Of Potential Pharmacological Activity.- Supramolecular Congo Red As Specific Ligand Of Antibodies Engaged In Immune Complex.- Protein Conditioning For Binding Congo Red And Other Supramolecular Lig

Self-Assembled Molecules – New Kind of Protein Ligands, Irena Roterman; Leszek Konieczny