Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com
Автор: Kulikov Название: Laser Interaction with Heterogeneous Biological Tissue ISBN: 3319941135 ISBN-13(EAN): 9783319941134 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces readers to the principles of laser interaction with biological cells and tissues with varying degrees of organization. In addition to considering the problems of biomedical cell diagnostics, and modeling the scattering of laser irradiation of blood cells for biological structures (dermis, epidermis, vascular plexus), it presents an analytic theory based on solving the wave equation for the electromagnetic field. It discusses a range of mathematical modeling topics, including optical characterization of biological tissue with large-scale and small-scale inhomogeneities in the layers; heating blood vessels using laser irradiation on the outer surface of the skin; and thermo-chemical denaturation of biological structures based on the example of human skin. In this second edition, a new electrodynamic model of the interaction of laser radiation with blood cells is presented for the structure of cells and the in vitro prediction of optical properties. The approach developed makes it possible to determine changes in cell size as well as modifications in their internal structures, such as transformation and polymorphism nucleus scattering, which is of interest for cytological studies. The new model is subsequently used to calculate the size distribution function of irregular-shape particles with a variety of forms and structures, which allows a cytological analysis of the observed deviations from normal cells.
Автор: Kirill Kulikov Название: Laser Interaction with Biological Material ISBN: 3319343815 ISBN-13(EAN): 9783319343815 Издательство: Springer Рейтинг: Цена: 13059.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This guide to laser interactions with a variety of biological cells and tissues delivers a practical analytical tool for assessing interference effects. It includes mathematical models and solutions to recognized problems in biomedical diagnostics.
Автор: James Lin Название: Electromagnetic Interaction with Biological Systems ISBN: 1468480618 ISBN-13(EAN): 9781468480610 Издательство: Springer Рейтинг: Цена: 13060.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Ever since the early 1940`s, electromagnetic energy in the nonionizing spectrum has contributed to the enhanced quality of life in a variety of ways.
Автор: R Paul Drake Название: High-Energy-Density Physics ISBN: 3319884735 ISBN-13(EAN): 9783319884738 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The raw numbers of high-energy-density physics are amazing: shock waves at hundreds of km/s (approaching a million km per hour), temperatures of millions of degrees, and pressures that exceed 100 million atmospheres. This title surveys the production of high-energy-density conditions, the fundamental plasma and hydrodynamic models that can describe them and the problem of scaling from the laboratory to the cosmos. Connections to astrophysics are discussed throughout. The book is intended to support coursework in high-energy-density physics, to meet the needs of new researchers in this field, and also to serve as a useful reference on the fundamentals. Specifically the book has been designed to enable academics in physics, astrophysics, applied physics and engineering departments to provide in a single-course, an introduction to fluid mechanics and radiative transfer, with dramatic applications in the field of high-energy-density systems. This second edition includes pedagogic improvements to the presentation throughout and additional material on equations of state, heat waves, and ionization fronts, as well as problem sets accompanied by solutions.
Описание: Several previous Advanced Study Institutes have concentrated on the techniques of light scattering, while the biological appli- cations were not fully explored.
Автор: Khan Amir Название: Earth`s Heterogeneous Mantle ISBN: 3319156268 ISBN-13(EAN): 9783319156262 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights and discusses recent developments that have contributed to an improved understanding of observed mantle heterogeneities and their relation to the thermo-chemical state of Earth`s mantle, which ultimately holds the key to unlocking the secrets of the evolution of our planet.
Описание: This doctoral thesisreports on an innovative data repository offering adaptive metadata managementto maximise information sharing and comprehension in multidisciplinary andgeographically distributed collaborations.
Автор: Martin Simon Название: Anomaly Detection in Random Heterogeneous Media ISBN: 3658109920 ISBN-13(EAN): 9783658109929 Издательство: Springer Рейтинг: Цена: 7685.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph is concerned with the analysis and numerical solution of a stochastic inverse anomaly detection problem in electrical impedance tomography (EIT). Moreover, the author proposes an efficient numerical method in the framework of Bayesian inversion for the practical solution of the stochastic inverse anomaly detection problem.
Автор: Peter Warneck; P. Mirabel; G.A. Salmon; C. Vinckie Название: Heterogeneous and Liquid Phase Processes ISBN: 3540607927 ISBN-13(EAN): 9783540607922 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The "European Experiment on the Transport and Transformation of Environmentally Relevant Trace Constituents over Europe" (EUROTRAC) was established in 1986 to tackle the scientific problem and combine the expertise, knowledge and resources in Europe, in order to apply them over a large region covering the greater part of the continent.
Автор: Peter J. Plath Название: Optimal Structures in Heterogeneous Reaction Systems ISBN: 3642839010 ISBN-13(EAN): 9783642839016 Издательство: Springer Рейтинг: Цена: 11173.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These were the circumstances that led to the idea of compiling some of the essential contributions presented at this seminar together with others describing basic features of "optimal struc- tures in heterogeneous reaction systems".
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