Imaging, Manipulation and Optogenetics in Zebrafish, Itia Amandine Favre?Bulle
Автор: Appasani Название: Optogenetics ISBN: 1107053013 ISBN-13(EAN): 9781107053014 Издательство: Cambridge Academ Рейтинг: Цена: 24394.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - has huge potential, with applications from brain circuits and sleep to neurodegenerative and neuropsychiatric diseases. This book is a reference for researchers and graduate students, as well as for those working in the biotechnology and pharmaceutical industries.
Автор: Albrecht Stroh Название: Optogenetics: A Roadmap ISBN: 1493974157 ISBN-13(EAN): 9781493974153 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience.
Автор: Favre?Bulle Название: Imaging, Manipulation and Optogenetics in Zebrafish ISBN: 3319962493 ISBN-13(EAN): 9783319962498 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It also demonstrates, for the first time, that directional and focused laser beams can successfully be used to target large objects at considerable depth in a living organism to exert purely optical force - in this case on otoliths (ear stones) - and create fictive vestibular stimuli in a stationary animal.
Автор: Albrecht Stroh Название: Optogenetics: A Roadmap ISBN: 1493984799 ISBN-13(EAN): 9781493984794 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.
Автор: Arash Kianianmomeni Название: Optogenetics ISBN: 1493935100 ISBN-13(EAN): 9781493935109 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides researchers with up-to-date protocols and takes aclose look at current research and promising applications.
Описание: Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans ( 75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book "The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling" explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.
Автор: Gerlai, Robert T. Название: Behavioral And Neural Genetics Of Zebrafish ISBN: 0128175281 ISBN-13(EAN): 9780128175286 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Поставка под заказ.
Описание:
The past decade has seen a rapid accumulation of knowledge on the behavioral characteristics of zebrafish, and their use in increased investigation into the neurobiological basis of behavior. This simple vertebrate represents an ideal compromise between system complexity and practical simplicity, with its mammalian sequence homology, fecundity, transparent embryology, and conveniently small size. Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and the most current concepts pertinent to their neurobehavioral genetics. Discussing its natural behavior, motor function, and learning and memory, it focuses on the fry and adult zebrafish and features a comprehensive account of modern genetic and neural methods adapted to or specifically developed for Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish will be presented, as well as a section on bioinformatics and big-data related questions. Focusing on this excellent translational tool, this book examines a species with which investigators may model and analyze even such complex human diseases as those associated with brain dysfunction.
Автор: Hiromi Hirata; Atsuo Iida Название: Zebrafish, Medaka, and Other Small Fishes ISBN: 9811318786 ISBN-13(EAN): 9789811318788 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: This book provides cutting-edge studies and technologies using small fishes, including zebrafish, medaka, and other fishes as new model animals for molecular biology, developmental biology, and medicine. It also introduces eccentric fish models that are pioneering new frontiers of biology. Zebrafish and medaka have been developed as lower vertebrate model organisms because these small fish are easy to raise in the laboratory and are useful for the live imaging of the morphology and activity of cells and tissues in intact animals. By virtue of those specific advantages, fish studies have demonstrated the common features of vertebrates and raised further questions toward understanding the mystery of life. The book consists of four parts: “Development and Cell Biology”, “Homeostasis and Reproduction”, “Clinical Models”, and “Eccentric Fish”. Together they describes the core area of small fish study – often considered mere zoology but which is actually proving to be the universal basis of life. Written by leading scientists, the book helps readers to understand small fishes, inspires scientists to utilize small fishes in their studies, and encourages anyone who wants to participate in the large and fantastic world of small fish.
Автор: Allan V. Kalueff; Jonathan M. Cachat Название: Zebrafish Neurobehavioral Protocols ISBN: 1493958844 ISBN-13(EAN): 9781493958849 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written in the Neuromethods format, this book reviews protocols in behavioral neuroscience, including assays used to quantify emotionality, learning, memory, and social behaviors, and shows how to quantify endocrine responses and correlate them with behavior.
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