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Multifunctional Gold Nanostars for Cancer Theranostics, Yang Liu


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Автор: Yang Liu
Название:  Multifunctional Gold Nanostars for Cancer Theranostics
ISBN: 9783030091040
Издательство: Springer
Классификация:






ISBN-10: 303009104X
Обложка/Формат: Soft cover
Страницы: 71
Вес: 0.16 кг.
Дата издания: 2018
Серия: Springer Theses
Язык: English
Издание: Softcover reprint of
Иллюстрации: 28 tables, color; 28 illustrations, color; xx, 71 p. 28 illus. in color.
Размер: 234 x 156 x 5
Читательская аудитория: General (us: trade)
Основная тема: Chemistry
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications.
Дополнительное описание: Introduction.- Multifunctional GNS nanoprobe development and characterization.- In vivo evaluation of GNS nanoprobe.- GNS toxicity investigation.- Sensitive brain tumor detection using GNS nanoprobe.- Photoimmunotherapy for cancer metastasis treatment.- C



Multifunctional Systems for Combined Delivery, Biosensing and Diagnostic

Автор: Grumezescu, Alexander Mih
Название: Multifunctional Systems for Combined Delivery, Biosensing and Diagnostic
ISBN: 0323527256 ISBN-13(EAN): 9780323527255
Издательство: Elsevier Science
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Цена: 26107.00 р.
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Описание: Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. . This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment.

Nanomedicines For Breast Cancer Theranostics

Автор: Thorat, Nanasaheb D.
Название: Nanomedicines For Breast Cancer Theranostics
ISBN: 0128200162 ISBN-13(EAN): 9780128200162
Издательство: Elsevier Science
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Цена: 28970.00 р.
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Описание:

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology.

Handbook of Nanomaterials for Cancer Theranostics

Автор: Conde, Joao
Название: Handbook of Nanomaterials for Cancer Theranostics
ISBN: 0128133392 ISBN-13(EAN): 9780128133392
Издательство: Elsevier Science
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Цена: 21054.00 р.
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Описание: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments.

Cancer Theranostics

Автор: Xiaoyuan Chen
Название: Cancer Theranostics
ISBN: 0124077226 ISBN-13(EAN): 9780124077225
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание:

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment.

Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives.

Core-Shell Nanostructures for Drug Delivery and Theranostics

Автор: Focarete, Maria
Название: Core-Shell Nanostructures for Drug Delivery and Theranostics
ISBN: 0081021984 ISBN-13(EAN): 9780081021989
Издательство: Elsevier Science
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Цена: 34529.00 р.
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Описание:

Core-shell nanostructures for drug delivery and theranostics brings together cutting-edge research to provide detailed coverage of core-shell nanoparticles and nanofibers for drug delivery, enabling scientists and researchers to understand the latest advances and applications in this field.

The development of polymeric drug delivery systems and technologies continues to present new possibilities in terms of controlled drug release and drug targeting capabilities. Core-shell nanostructures offer many benefits, such as temporal-spatial controlled release, drug/biomolecule protection from harsh environments, and multi-drug release, and may therefore be utilized in advanced and challenging applications.

The opening part of the book deals with the fundamentals of nanotechnology for drug delivery. The second part of the book covers the recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications. The third part addresses the potential and applications of core-shell nanofiber.

This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry.

  • Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release
  • Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics
  • Explains the principles and essential concepts of nanotechnology for drug delivery systems
Design of Nanostructures for Theranostics Applications

Автор: Grumezescu, Alexandru
Название: Design of Nanostructures for Theranostics Applications
ISBN: 0128136693 ISBN-13(EAN): 9780128136690
Издательство: Elsevier Science
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Цена: 26107.00 р.
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Описание:

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry.

  • Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots
  • Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders
  • Assesses the pros and cons of using different nanomaterials for different types of treatment
SPIONs as Nano-Theranostics Agents

Автор: Atefeh Zarepour; Ali Zarrabi; Arezoo Khosravi
Название: SPIONs as Nano-Theranostics Agents
ISBN: 9811035628 ISBN-13(EAN): 9789811035623
Издательство: Springer
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Цена: 9141.00 р.
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Описание: This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.

Mesoscopic Phenomena in Multifunctional Materials

Автор: Avadh Saxena; Antoni Planes
Название: Mesoscopic Phenomena in Multifunctional Materials
ISBN: 3642553745 ISBN-13(EAN): 9783642553745
Издательство: Springer
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Цена: 20896.00 р.
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Описание: A highly coveted objective of modern materials science is to optimize multiple coupled functionalities in the same single phase material and control the cross-response via multiple external fields.

Multifunctional Polycrystalline Ferroelectric Materials

Автор: Lorena Pardo; Jes?s Ricote
Название: Multifunctional Polycrystalline Ferroelectric Materials
ISBN: 9400735324 ISBN-13(EAN): 9789400735323
Издательство: Springer
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Цена: 26120.00 р.
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Описание: Ceramics are key materials in many devices using piezoelectricity in numerous applications, but the ferroelectric nature of such ceramics is little understood. This book covers an array of topics on the processing and properties of ferroelectric materials.

Multifunctional Gold Nanostars for Cancer Theranostics

Автор: Liu
Название: Multifunctional Gold Nanostars for Cancer Theranostics
ISBN: 3319749196 ISBN-13(EAN): 9783319749198
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Introduction.- Multifunctional GNS nanoprobe development and characterization.- In vivo evaluation of GNS nanoprobe.- GNS toxicity investigation.- Sensitive brain tumor detection using GNS nanoprobe.- Photoimmunotherapy for cancer metastasis treatment.- Conclusion and future outlook.

Nanomaterials For Theranostics And Tissue Engineering

Автор: Rossi, Fillipo
Название: Nanomaterials For Theranostics And Tissue Engineering
ISBN: 0128178388 ISBN-13(EAN): 9780128178386
Издательство: Elsevier Science
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Цена: 26444.00 р.
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Описание:

Nanomaterials for Theranostics and Tissue Engineering: Techniques, Trends and Applications provides information on the major methodologies for the application of nanomaterials in the medical field. In recent years, nanotechnology for medicine, commonly known as bionanotechnology, or nanomedicine, has revolutionized various types of medical treatment. This book is intended for practicing engineers and scientists, and includes detailed, readily applicable protocols. It focuses on 4 major themes, including the synthesis of nanosystems for controlled drug delivery, nanotechnology-enhanced sensing systems, the application of nanotechnologies to the synthesis of novel biomaterials, and safety issues related to the application of medicinal nanotechnology.

Hybrid Nanostructures for Cancer Theranostics

Автор: Ashok Bohara, Raghvendra
Название: Hybrid Nanostructures for Cancer Theranostics
ISBN: 0128139064 ISBN-13(EAN): 9780128139066
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание:

Hybrid nanostructures are nanoparticles which incorporate two or more structures. These structures may represent organic or inorganic material, but they synergistically improve the application of the material for end users. Hybrid Nanostructures for Cancer Theranostics explores how hybrid nanostructures are used in cancer treatment.

Focusing on the properties of hybrid nanostructures, the book demonstrates how their unique characteristics can be used to create more effective treatment techniques. In the second half of the book, the chapters examine how hybrid nanostructures are currently being used in practice, assessing the pros and cons of using different types of nanostructures for different treatments.

This valuable resource will allow readers to understand the core and emerging concept of functionalization, bioconjugation, hyperthermia and phototherapy of nanoparticles which allows for the greater use of hybrid nanomaterials in cancer theranostics.

  • Shows how the use of novel hybrid nanostructures can lead to more effective cancer treatments.
  • Explores how hybrid nanostructures are used for different treatment types, including photo thermal therapy and drug delivery.
  • Explains how the use of hybrid nanostructures can lead to more rapid cancer diagnosis.

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