Описание: Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression.
Автор: William C.S. Cho Название: MicroRNAs in Cancer Translational Research ISBN: 9400789971 ISBN-13(EAN): 9789400789975 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This timely publication includes chapters by world-renowned experts and focuses on our current understanding of miRNAs. It assesses their potential applications in cancer diagnosis, prognosis and therapeutic targets, and identifies areas for further research.
Автор: Michael Sand Название: MicroRNAs in malignant tumors of the skin ISBN: 3658215119 ISBN-13(EAN): 9783658215118 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Michael Sand gives the reader an overview ofcurrent techniques in expression profiling of miRNAs and their maturationmachinery in the skin. This book is a postdoctoral thesis on miRNAs incutaneous malignant melanoma and non-melanoma skin cancer with a focus on themiRNA processing machinery and miRNA expression profiling.
Автор: Catherine M. Greene Название: MicroRNAs and Other Non-Coding RNAs in Inflammation ISBN: 3319382306 ISBN-13(EAN): 9783319382302 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e.
Автор: Sadegh Babashah Название: MicroRNAs: Key Regulators of Oncogenesis ISBN: 3319376136 ISBN-13(EAN): 9783319376134 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.
Автор: Sand Название: MicroRNAs in malignant tumors of the skin ISBN: 3658127937 ISBN-13(EAN): 9783658127930 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Michael Sand gives the reader an overview ofcurrent techniques in expression profiling of miRNAs and their maturationmachinery in the skin. This book is a postdoctoral thesis on miRNAs incutaneous malignant melanoma and non-melanoma skin cancer with a focus on themiRNA processing machinery and miRNA expression profiling. The researchpresented in this book was performed in the Dermatologic Surgery Section at theDepartment of Dermatology, Venereology and Allergology of the Ruhr-UniversityBochum, Germany and gives the reader an overview of current techniques inexpression profiling of miRNAs and their maturation machinery in the skin.
Автор: Laurence, Jeffrey Название: Translating MicroRNAs to the Clinic ISBN: 012800553X ISBN-13(EAN): 9780128005538 Издательство: Elsevier Science Рейтинг: Цена: 16338.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others.
Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.
Автор: Sadegh Babashah Название: MicroRNAs: Key Regulators of Oncogenesis ISBN: 3319037242 ISBN-13(EAN): 9783319037240 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state.
Автор: Wei Wu Название: MicroRNA and Cancer ISBN: 1493957740 ISBN-13(EAN): 9781493957743 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Authoritative and cutting-edge, this book provides the basic principles of experimental and computational methods for microRNA study in cancer research. It provides a firm grounding for those who wish to further develop their own applications.
Автор: Fazlul H. Sarkar Название: MicroRNA Targeted Cancer Therapy ISBN: 3319051334 ISBN-13(EAN): 9783319051338 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The most attractive feature of miRNAs is that one miRNA can regulate many target genes (mRNAs) and thus miRNA targeted therapy is highly promising because multiple genes could be regulated by targeting a single miRNA, which becomes very important for the killing of highly heterogeneous populations of cancer cells within a tumor mass.
Автор: Singh Shree Ram Название: MicroRNA in Development and in the Progression of Cancer ISBN: 1489980644 ISBN-13(EAN): 9781489980649 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-? and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.
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