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The Genetics and Development of Scoliosis, Kenro Kusumi; Sally L. Dunwoodie


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Цена: 13974.00р.
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При оформлении заказа до: 2025-09-29
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Автор: Kenro Kusumi; Sally L. Dunwoodie
Название:  The Genetics and Development of Scoliosis
ISBN: 9783030079444
Издательство: Springer
Классификация:




ISBN-10: 3030079449
Обложка/Формат: Soft cover
Страницы: 199
Вес: 0.33 кг.
Дата издания: 2018
Язык: English
Издание: Softcover reprint of
Иллюстрации: 12 illustrations, color; 17 illustrations, black and white; xii, 199 p. 29 illus., 12 illus. in color.
Размер: 234 x 156 x 11
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.

Дополнительное описание: Chapter1: Developmental and Functional Anatomy of the Spine.- Chapter2: Environmental Factors and Axial Skeletal Dysmorphogenesis.- Chapter3: Congenital Scoliosis and Segmentation Defects of the Vertebrae in the Genetic Clinic.- Chapter4: The Genetics Con



The Genetics and Development of Scoliosis

Автор: Kusumi
Название: The Genetics and Development of Scoliosis
ISBN: 3319901486 ISBN-13(EAN): 9783319901480
Издательство: Springer
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Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Recent genetic studies of the spine has enhanced the understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. These findings are discussed in this timely review of scoliosis and developmental studies of the spine.

The Genetics and Development of Scoliosis

Автор: Kenro Kusumi; Sally L. Dunwoodie
Название: The Genetics and Development of Scoliosis
ISBN: 1489982965 ISBN-13(EAN): 9781489982964
Издательство: Springer
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Цена: 26120.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Recent genetic studies of the spine has enhanced the understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. These findings are discussed in this timely review of scoliosis and developmental studies of the spine.

Early Onset Scoliosis

Автор: El-Hawary, Ron, Eberson, Craig P.
Название: Early Onset Scoliosis
ISBN: 3319715798 ISBN-13(EAN): 9783319715797
Издательство: Springer
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Цена: 18167.00 р.
Наличие на складе: Поставка под заказ.

Описание: Comprised exclusively of clinical cases demonstrating the management of idiopathic, congenital, syndromic and neuromuscular early onset scoliosis (EOS), this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the differing presentations of EOS they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, clinical pearls and pitfalls, and literature review. Cases included illustrate different types and management strategies for EOS, including various spine-based growing rods, the vertical expandable prosthetic titanium rib (VEPTR), anterior vertebral body tethering (AVBT) and congenital resection. Treatment strategies for EOS with related conditions such as myelomeningocele, cerebral palsy and skeletal dysplasia are also discussed, as are common complications and the role of traction.Pragmatic and reader-friendly, Early Onset Scoliosis: A Clinical Casebook is an excellent resource for pediatric orthopedic surgeons and other physicians confronted with both common and complex disorders of the child’s spine.

Three-Dimensional Treatment for Scoliosis

Автор: Lehnert-Schroth, Christa
Название: Three-Dimensional Treatment for Scoliosis
ISBN: 0914959026 ISBN-13(EAN): 9780914959021
Издательство: Неизвестно
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Цена: 8270.00 р.
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Описание: Causation is asymmetrical in many different ways. Causes precede effects; explanations cite causes not effects. Agents use causes to manipulate their effects; they don`t use effects to manipulate their causes. Effects of a common cause are correlated; causes of a common effect are not. This is a major book for philosophers of science that will also prove insightful to economists and statisticians.

Bioinformatics and Computational Biology in Drug Discovery and Development

Автор: Loging
Название: Bioinformatics and Computational Biology in Drug Discovery and Development
ISBN: 0521768004 ISBN-13(EAN): 9780521768009
Издательство: Cambridge Academ
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Цена: 9186.00 р.
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Описание: Providing a comprehensive overview of the drug discovery and development pipeline, this book focuses on the integral role that computational biology methods play in this process. Covering technological advances and their relation to drug developmental processes, readers are exposed to new methods of discovery utilising the available technology.

Post-genomic Approaches in Drug and Vaccine Development

Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
Название: Post-genomic Approaches in Drug and Vaccine Development
ISBN: 8793102844 ISBN-13(EAN): 9788793102842
Издательство: Taylor&Francis
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Цена: 13320.00 р.
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Описание: Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, and understand their role in physiological pathways and associated diseases with the aim of translating these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic, and metabolomic approaches. Post-genomic Approaches to Drug and Vaccine Development focuses on some key advances in the field.

Technical topics discussed in the book include:
- Drug discovery
- Target identification and prioritization
- Hypothesis driven multi-target drug design
- Genomics in vaccine development
- Gene regulatory networks
- Vaccine design and development
- Prediction of drug side effects in silico


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