Автор: Leonora Buzanska Название: Human Neural Stem Cells ISBN: 3319934848 ISBN-13(EAN): 9783319934846 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic mode of action.The long-standing dogma that the human central nervous system (CNS) lacks the ability to regenerate was refuted at the end of the 20th century, when evidence of the presence of neurogenic zones in the adult human brain was found. These neurogenic zones are home to human neural stem cells (hNSCs), which are capable of self-renewing and differentiating into neurons, astrocytes and oligodendrocytes. NSCs isolated from human CNS have a number of clinical advantages, especially the innate potential to differentiate into functional neural cells. Nevertheless, their full clinical exploitation has been hindered by limited access to the tissue and low expansion potential. The search for an alternative to CNS sources of autologous, therapeutically competent hNSCs was the driving force for the many studies proving the in vitro plasticity of different somatic stem cells to generate NSCs and their functional progeny. Now the era of induced pluripotent stem cells has opened entirely new opportunities to achieve research and therapeutic goals with the aid of hNSCs.
Автор: Mahendra S. Rao; Melissa Carpenter; Mohan C. Vemur Название: Neural Development and Stem Cells ISBN: 1489996206 ISBN-13(EAN): 9781489996206 Издательство: Springer Рейтинг: Цена: 30039.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Authoritative and up-to-date in its 3rd edition, this book provides neuroscientists with a guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
Автор: H. Georg Kuhn; Amelia J. Eisch Название: Neural Stem Cells in Development, Adulthood and Disease ISBN: 1493953613 ISBN-13(EAN): 9781493953615 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells.
Автор: Shetty Ashok K. Название: Neural Stem Cells in Health and Disease ISBN: 9814623172 ISBN-13(EAN): 9789814623179 Издательство: World Scientific Publishing Рейтинг: Цена: 15523.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a comprehensive guide on neural stem cell behavior in health and disease.
Автор: Jane E. Bottenstein Название: Neural Stem Cells ISBN: 140207588X ISBN-13(EAN): 9781402075889 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides data on neural stem cell properties and their therapeutic applications. This volume is suitable for students, basic scientists, and clinicians in the academic or industrial sectors who have an interest in understanding neural development and its application to repairing the nervous system.
Автор: Marcel M. Daadi Название: Neural Stem Cells ISBN: 1493990055 ISBN-13(EAN): 9781493990054 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Нет в наличии.
Описание: This volume details various technological advances to isolate, perpetuate, and characterize neural stem cells from various sources and formulates them for the delivery into animal models of neurological disorders. Chapters guide the reader through methods and protocols on definition and isolation of neural stem cells, characterization and differentiation, standards for defining cell populations, and In vivo approaches in animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Neural Stem Cells: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Автор: Freshney Название: Culture of Human Stem Cells ISBN: 0470052465 ISBN-13(EAN): 9780470052464 Издательство: Wiley Рейтинг: Цена: 24394.00 р. Наличие на складе: Поставка под заказ.
Описание: This book collects the most effective and cutting-edge methods and protocols for deriving and culturing human embryonic and adult stem cells-in one handy
resource. This groundbreaking book follows the tradition of previous books in the "Culture of Specialized Cells Series" - each methods and protocols chapter is laid out exactly like the
next, with stepwise protocols, preceded by specific requirements for that protocol, and a concise discussion of methods illustrated by data. The editors describe a limited number of
representative techniques across a wide spectrum of stem c
lls from embryonic, newborn, and adult tissue, yielding an all-encompassing and versatile guide to the field of stem cell biology and culture.
The book includes a
comprehensive list of suppliers for all equipment used in the protocols presented, with websites available in an appendix. Additionally, there is a chapter on quality control, and other
chapters covering legal and ethical issues, cryopreservation, and feeder layer culture. This text is a one-stop resource for all researchers, clinical scientists, teachers, and students
involved in this crucial area of study.
Автор: Michal Amit; Joseph Itskovitz-Eldor Название: Atlas of Human Pluripotent Stem Cells ISBN: 1493957864 ISBN-13(EAN): 9781493957866 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive atlas offers step-by-step guidance for the derivation and culturing of human pluripotent stem cells in defined conditions and in non-adhesion suspension culture, as well as methods for examining pluripotency and karyotype stability.
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