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Systematic Exploration of Indolizine-Based Small Fluorescent Molecules, Youngjun Lee


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Автор: Youngjun Lee
Название:  Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
ISBN: 9789811346606
Издательство: Springer
Классификация:





ISBN-10: 9811346607
Обложка/Формат: Soft cover
Страницы: 187
Вес: 0.34 кг.
Дата издания: 2018
Серия: Springer Theses
Язык: English
Издание: Softcover reprint of
Иллюстрации: 90 illustrations, color; 107 illustrations, black and white; xxv, 187 p. 197 illus., 90 illus. in color.
Размер: 234 x 156 x 12
Читательская аудитория: General (us: trade)
Основная тема: Chemistry
Подзаголовок: Synthesis, Analysis and Application
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:
This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter.Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions.Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

Дополнительное описание: Abstract.- Table of Contents.- List of Figures.- List of Tables.- List of Schemes.- List of Abbreviations.- Chapter 1. Introduction.- 1.1 Molecular Fluorescence and Photophysical Parameters.- 1.2 Organic Fluorophores.- 1.3 Aims and Scope of the Thesis.- 1



Fluorescent Protein-Based Biosensors

Автор: Jin Zhang; Qiang Ni; Robert H Newman
Название: Fluorescent Protein-Based Biosensors
ISBN: 1493960148 ISBN-13(EAN): 9781493960149
Издательство: Springer
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Цена: 14673.00 р.
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Описание: This book features step-by-step, readily reproducible protocols used to describe several methods in which fluorescent protein-based reporters can be used to gain unique insights into the regulation of cellular signal transduction.

Fluorescent Proteins II

Автор: Gregor Jung
Название: Fluorescent Proteins II
ISBN: 3642446825 ISBN-13(EAN): 9783642446825
Издательство: Springer
Рейтинг:
Цена: 44582.00 р.
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Описание: The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of a broad palette of fluorescence proteins of other colours, was consequently recognised with the Nobel Prize for Chemistry in 2008.

Fluorescence Microscopy and Fluorescent Probes

Автор: J. Slav?k
Название: Fluorescence Microscopy and Fluorescent Probes
ISBN: 148991868X ISBN-13(EAN): 9781489918680
Издательство: Springer
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Цена: 22203.00 р.
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Описание: Fluorescence microscopy images can be easily integrated into current video and computer image processing systems. It also makes it possible to compute ratio images (ratio imaging both in excitation and in emission) or lifetime imaging.

Systematic Exploration of Indolizine-Based Small Fluorescent Molecules

Автор: Lee
Название: Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
ISBN: 9811316449 ISBN-13(EAN): 9789811316449
Издательство: Springer
Рейтинг:
Цена: 13974.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter.

Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions.

Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

Fluorescent Protein-Based Biosensors

Автор: Jin Zhang; Qiang Ni; Robert H Newman
Название: Fluorescent Protein-Based Biosensors
ISBN: 1627036210 ISBN-13(EAN): 9781627036214
Издательство: Springer
Рейтинг:
Цена: 14673.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book features step-by-step, readily reproducible protocols used to describe several methods in which fluorescent protein-based reporters can be used to gain unique insights into the regulation of cellular signal transduction.

Fluorescent Tools for Imaging Oxidative Stress in Biology

Автор: Kaur
Название: Fluorescent Tools for Imaging Oxidative Stress in Biology
ISBN: 3319734040 ISBN-13(EAN): 9783319734040
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Introduction.- Flavin based redox probes.- FRET based ratiometric redox probes.- Mitochondrially-targeted ratiometric redox probes.- Nicotinamide based ratiometric probes.- In cellulo studies.- Ex vivo studies.- Non-mammalian systems.- Conclusions.- Experimental Methods.

Fluorescent Methods for Molecular Motors

Автор: Toseland Christopher P.
Название: Fluorescent Methods for Molecular Motors
ISBN: 3034808550 ISBN-13(EAN): 9783034808552
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
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Описание: This book focuses on the application of fluorescence to study motor proteins (myosins, kinesins, DNA helicases and RNA polymerases). It is intended for a large community of biochemists, biophysicists and cell biologists who study a diverse collection of motor proteins. It can be used by researchers to gain an insight into their first experiments, or by experienced researchers who are looking to expand their research to new areas. Each chapter provides valuable advice for executing the experiments, along with detailed background knowledge in order to develop own experiments.

Fluorescence Microscopy and Fluorescent Probes

Автор: Jan Slav?k
Название: Fluorescence Microscopy and Fluorescent Probes
ISBN: 0306460211 ISBN-13(EAN): 9780306460210
Издательство: Springer
Рейтинг:
Цена: 19591.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The April 1997 conference held in Prague attracted the cream of primarily European and Russian researchers (with a handful from the US, primarily from the U. of Maryland School of Medicine) to the burgeoning biological and medical applications of innovative optical technology, particularly laser con

Fluorescent Biomolecules

Автор: David M. Jameson; Gregory D. Reinhart
Название: Fluorescent Biomolecules
ISBN: 1468456210 ISBN-13(EAN): 9781468456219
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Suffice it to say that since his initial landmark articles on fluorescence, published in the late 1940`s and early 1950`s, Gregorio Weber has continued to make seminal contribu- tions to both the theory and practice of fluorescence and, contrary to many who might be tempted to rest on their laurels, he shows no signs of slackening his pace.

The Fluorescent Protein Revolution

Название: The Fluorescent Protein Revolution
ISBN: 0367378701 ISBN-13(EAN): 9780367378707
Издательство: Taylor&Francis
Рейтинг:
Цена: 9798.00 р.
Наличие на складе: Поставка под заказ.

Описание:

Advances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revolution explores the history, properties, and applications of these important probes.

The book first traces the history of fluorescent proteins and the revolution they enabled in cellular imaging. It then discusses fluorescent proteins with novel photophysical properties. The book also covers several cutting-edge imaging applications. These include superresolution microscopy of cellular fine structures, FRET microscopy to visualize protein interactions and cell-signaling activities inside living cells, photobleaching and photoactivation techniques to visualize protein behaviors, techniques that exploit plant and algal photoreceptors to enable light-regulated control of enzymatic activities, and the noninvasive imaging of tumor-host interactions in living animals.

In color throughout, this book presents the fundamental principles and latest advances in the field, including the associated development of imaging techniques that exploit fluorescent proteins. It is accessible to a broad audience, from optical imaging experts to novices needing an introduction to the field.

Fluorescent Proteins I

Автор: Gregor Jung
Название: Fluorescent Proteins I
ISBN: 3642269710 ISBN-13(EAN): 9783642269714
Издательство: Springer
Рейтинг:
Цена: 36570.00 р.
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Описание: Fluorescent proteins are intimately connected to research in the life sciences. The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of a broad palette of fluorescence proteins of other colours, was consequently recognised with the Nobel Prize for Chemistry in 2008.

Analytical Use of Fluorescent Probes in Oncology

Автор: Elli Kohen; Joseph G. Hirschberg
Название: Analytical Use of Fluorescent Probes in Oncology
ISBN: 1461376793 ISBN-13(EAN): 9781461376798
Издательство: Springer
Рейтинг:
Цена: 27950.00 р.
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Описание: Proceedings of a NATO ARW held in Miami, Florida, October 14-18, 1995.


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