Автор: Sellin Mitch Название: Essential Guide to Systemic Lupus Erythematosus ISBN: 1632410419 ISBN-13(EAN): 9781632410412 Издательство: Неизвестно Цена: 18507.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book deals with the fundamentals and sciences of Systemic Lupus Erythematosus. It is an apt resource for scientists seeking extensive coverage of their spheres of interest. The book delves into the progress of molecular biology and how it has enhance
Автор: Paul Eggleton; Frank J. Ward Название: Systemic Lupus Erythematosus ISBN: 1493952625 ISBN-13(EAN): 9781493952625 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Systemic Lupus Erythematosus: Methods and Protocols describes a number of genetic, biochemical and immunological techniques.These techniques provide an?advancing understanding of the pathology, breakdown of the immune system, and therapeutic challenges of SLE in both humans and animal models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.--
Автор: Eggleton Название: Systemic Lupus Erythematosus ISBN: 149390325X ISBN-13(EAN): 9781493903252 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Shunsei Hirohata Название: Neuropsychiatric Systemic Lupus Erythematosus ISBN: 3030095037 ISBN-13(EAN): 9783030095031 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Neuropsychiatric manifestation in systemic lupus erythematosus (NPSLE) is one of the most recalcitrant complications of the disease. According to the 1999 ACR nomenclature and case definitions, diffuse psychiatric/neuropsychological syndromes in NPSLE (anxiety disorder, acute confusional state, cognitive dysfunction, mood disorder, psychosis) (diffuse NPSLE) present psychiatric manifestations unlike neurologic syndromes (focal NPSLE) originating from focal CNS lesions, such as cerebrovascular disease, demyelinating syndrome, headache, aseptic meningitis, chorea, seizures and myelopathy. A number of studies have reported that diffuse NPSLE is usually associated with the presence of autoantibodies against neuronal cells in serum as well as in cerebrospinal fluid (CSF). Moreover, IL-6 has been shown to be elevated in CSF of patients with diffuse NPSLE.Recently, it has been demonstrated that the severity of blood-brain barrier damages plays a crucial role in the development of acute confusional state, the severest form of diffuse NPSLE through the accelerated entry of larger amounts of autoantibodies to NMDA receptor subunit NR2 into the CNS. Since the importance of autoantibodies in the NPSLE has been now evident, such an aggressive treatment, especially B cell depleting therapy, would make sense in that it would reduce the levels of pathogenic autoantibodies, leading to a better prognosis of NPSLE.As far as we know, no single book specifically dedicated to NPSLE alone has been published as yet. As mentioned above, NPSLE constitutes a vastly expanding field of research with increasing numbers of papers published annually. Therefore, we believe that an effort to collect and critically review these publications is invaluable. Such an effort will provide an important contribution to basic researchers as well as clinicians working in the field of neurology, rheumatology, psychiatry and internal medicine fields.
Автор: Meyer Jasper Название: Systemic Lupus Erythematosus: An Autoimmune Disease ISBN: 1632428520 ISBN-13(EAN): 9781632428523 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Peter A. Miescher Название: Systemic Lupus Erythematosus ISBN: 3642796249 ISBN-13(EAN): 9783642796241 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: During the past 50 years, systemic lupus erythematosus (SLE) has been the main subject in the field of immunopathology. Similarly, research on cytokines in SLE patients has shown that SLE is a syndrome depending on different pathways.
Автор: George C. Tsokos Название: Systemic Lupus Erythematosus ISBN: 0128019174 ISBN-13(EAN): 9780128019177 Издательство: Elsevier Science Рейтинг: Цена: 16212.00 р. Наличие на складе: Поставка под заказ.
Описание: Systemic Lupus Erythematosus combines basic science with clinical science to provide a translational treatment of the disease and is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.
Автор: Josef S. Smolen; G. Geyer; Christoph C. Zielinski Название: Systemic Lupus Erythematosus ISBN: 364271644X ISBN-13(EAN): 9783642716447 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: More than 140 years ago, lupus erythematosus (LE) was recognized as a disease entity by clinicians working in the field of dermatology, which had only recently become an independent medical discipline.
Автор: Sellin Mitch Название: Systemic Lupus Erythematosus ISBN: 1632413639 ISBN-13(EAN): 9781632413635 Издательство: Неизвестно Цена: 26843.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book extensively deals with the fundamentals and medical sciences related to Systemic Lupus Erythematosus. It is an apt resource for scientists seeking extensive coverage of their spheres of interest. The book delves into the progress of molecular bi
Автор: Gene S. Fisch; Jonathan Flint Название: Transgenic and Knockout Models of Neuropsychiatric Disorders ISBN: 1617376078 ISBN-13(EAN): 9781617376078 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond.
Автор: Yasui, Dag Название: Neuropsychiatric Disorders and Epigenetics ISBN: 0128002263 ISBN-13(EAN): 9780128002261 Издательство: Elsevier Science Рейтинг: Цена: 13980.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease.
Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development.
Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction
Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists
Extensive use of diagrams, illustrations, tables, and graphical abstracts for each section providing rapid assessment
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
