Автор: S. Samuel Kim Название: Oocyte Biology in Fertility Preservation ISBN: 1493945742 ISBN-13(EAN): 9781493945740 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms. To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics.
Автор: Verlhac Название: Mouse Oocyte Development ISBN: 1493986023 ISBN-13(EAN): 9781493986026 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Growth In Vitro of Granulosa Cell-oocyte Complexes of the Mouse
Stephany El-Hayek, Qin Yang, and Hugh J. Clarke
2. In vitro Culture of Mouse Oocytes for Meiotic Maturation
Ewa Borsuk and Jacek Z. Kubiak
3. In vitro Maturation and Culture of Human Oocytes
Jennifer R Gruhn, Stine Gry Kristensen, Claus Yding Andersen, and Eva R Hoffmann
4. Pronuclear Transfer in Human Oocytes
Louise Hyslop
5. In vitro Fertilization of Mouse Oocyte
Agathe Chaigne
6. Profiling Maternal mRNA Translation during Oocyte Development
Joao P. Sousa Martinsand Marco Conti
7. Transcriptome Profiling of Single Mouse Oocytes
Maud Borensztein, Laurиne Syx, Nicolas Servant, and Edith Heard
8. Immunofluorescence Technique to Detect Subcellular Structures Critical to Oocyte Maturation
Cecilia S. Blengini and Karen Schindler
9. Immunofluorescence Staining of K-fibres in Mouse Oocytes Using Cold-fixation
Jessica Greaney, Zhe Wei, and Hayden Homer
10. Triple-colour Live Imaging of Mouse Oocytes
Aurйlien Courtois, Petr Solc, and Tomoya S. Kitajima
11. Detection of Separase Activity Using a Cleavage Sensor in Live Mouse Oocytes
Elvira Nikalayevich, Nora Bouftas, and Katja Wassmann
12. Manipulating Cohesin Levels in Live Mouse Oocytes
Anna Szydlowska, Sabrina Ladstдtter, and Kikuл Tachibana
13. Optogenetic Manipulation of Mouse Oocytes
Takashi Akera, David M. Chenoweth, and Michael A. Lampson
14. Monitoring Microtubule Dynamics in the Mouse Egg using PhotoActivatableGFP-tubulin
Greg FitzHarris
15. Photoactivation of Actin in Mouse Oocyte
Maria Almonacid
16. Laser Ablation of Microtubule-chromosome Attachment in Mouse Oocytes
Isma Bennabiand Marion Manil-Sйgalen
17. Micropipette Aspiration of Oocytes to Assess Cortical Tension
Описание: This volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of an embryo. Germ cells are uniquely poised to sustain life across generations through the fusion of oocyte and sperm. Because of the central importance of germ cells to life, much work has been dedicated to obtaining a clear understanding of the molecular and signaling events that control their formation and maintenance. Germ cells are set aside from somatic cells in the embryo and go through specialized meiotic cell cycles as the animal matures. These cell cycles are interspersed with long periods of arrest. In human females, meiosis I is initiated in the fetus. At birth, oocytes are arrested in meiosis I; after puberty, every month an oocyte initiates meiosis II – ovulation. Upon sperm availability these cells are fertilized, generate an embryo, and the cycle-of-life continues. During meiotic I progression and arrest, the fitness of oocytes and their progeny are likely influenced by environmental cues and signaling pathways. A lot of recent work has focused on understanding the mechanisms that regulate oocyte fitness and quality in humans and vertebrates. Much of our understanding on the events of meiosis I and germline stem cell populations comes from work in invertebrates, wherein the germline stem cells produce oocytes continuously through adult development. In both inverbrates and vertebrates nutritional and signaling pathways control the regulation of stem cells in such a manner so as to couple production of gametes with the nutritional availability. Additionally, mature oocytes arrest both in meiosis I and meiosis II, and signaling and nutritional pathways have been shown to regulate their formation, and maintenance, such that despite long periods of arrest, the oocyte quality is assured and errors in chromosome segregation and varied cytoplasmic events are minimal.
Автор: Hayden A. Homer Название: Mammalian Oocyte Regulation ISBN: 1493959409 ISBN-13(EAN): 9781493959402 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) volume offers methodologies enabling researchers to interrogate every aspect of mammalian oocyte development including recombination, meiotic maturation, oocyte substrate uptake, chromosomal segregation and fertilisation.
Автор: Swathi Arur Название: Signaling-Mediated Control of Cell Division ISBN: 3319448196 ISBN-13(EAN): 9783319448190 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 1. Role of chromatin modifications in germline stem cell differentiationPooja Flora, Maitreyi Upadhyay, Alicia McCarthy, Prashanth Rangan Prashanth Rangan prangan@albany.edu 2. Regulation of the balance between proliferation and differentiation in germline stem cells.Ramya Singh and David HansenDavid Donald Hansen dhansen@ucalgary.ca 3. Control of germ line stem cell lineages by diet and physiologyKaitlyn Laws and Daniela Drummond-BarbosaDaniela Barbosa dbarbosa@jhu.edu 4. Signal-mediated regulation of meiotic prophase I during oogenesisKenneth Trimmer and Swathi ArurSwathi Arur sarur@mdanderson.org 5. Prophase I: preparing chromosomes for segregation in the developing oocyteRachel Harney, Benjamin Alleva, Sarit SmolikovSarit Smolikov saritsmol@gmail.com 6. Translational control of germ cell decisionsKumari Pushpa, Amaresh Chaturbedi, Ganga Anil Kumar and Kuppuswamy SubramaniamK Subramaniam subbu@iitm.ac.in 7. Prostagladin signaling from oocyte to spermHieu Dinh Hoang and Michael MillerMichael Miller mamiller@uab.edu 8. Cell fate maintenance and reprogramming during the oocyte-to-embryotransition'Christina Fassnacht and Rafal CioskRafal Ciosk rafal.ciosk@fmi.ch 9. Maternal to zygotic transitions across evolutionRueyling Lin rueyling.lin@utsouthwestern.edu 10 Cell cycle regulation in oocytesKubiak JZ and Borsuk EUniversity of Rennes, FranceJacek Kubiak. jacek.kubiak@univ-rennes1.fr 11 Oocyte activation and fertilization: crucial sperm and oocyte factorsMarc Yeste, Celine Jones, Siti N. Amdani, Kevin CowardUniversity of OxfordMarc Yeste. marc.yeste@obs-gyn.ox.ac.uk
Автор: Malgorzata Kloc Название: Oocytes ISBN: 3319869442 ISBN-13(EAN): 9783319869445 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Поставка под заказ.
Описание: This book combines the most recent knowledge on the maternal, i.e. oocyte/egg-specific, molecules and processes. The volume covers the most recent advances in a plethora of subjects such as: maternal transfer of immunity, localized RNAs functions and mechanisms of RNA localization, transcriptional repression of maternal messages, maternal inheritance and maternal role of CRISPR/Cas9-based genome editing, chromatin remodeling and epigenetic modifications, maternal function of nucleosomes, maternal mitochondria and energy supply, role of bacterial symbionts and their maternal transmission, acquisition of oocyte polarity and evolution of maternal effect genes, germ plasm and oosome origin and functions, mechanisms of oocyte activation and soma germ cells communication. Currently, no other book on the market combines such a comprehensive list of subjects in one volume. Moreover, the information provided is a cross-section through oocytes from various inv ertebrate and vertebrate species, which is another unique feature of this book. The readers, therefore, get a completely new and invaluable perspective on all covered subjects.
Автор: Malgorzata Kloc Название: Oocytes ISBN: 3319608541 ISBN-13(EAN): 9783319608549 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Jacek Z. Kubiak Название: Mouse Development ISBN: 3642440819 ISBN-13(EAN): 9783642440816 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Written by leading specialists, this valuable source for developmental biologists and researchers in IVF and human embryology includes the latest advances, from oocytes before fertilization to a state-of-the-art description of embryonic and adult stem cells.
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