Stephen D. Skaper Neurotrophic Factors 9781493985241

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Автор: Stephen D. Skaper
Название: Neurotrophic Factors
ISBN: 9781493985241
Издательство: Springer
Классификация:

Социология: работа и рабочая сила

Науки о жизни (медико-биологические): общие вопросы

Нейронауки

ISBN-10: 1493985248
Обложка/Формат: Soft cover
Страницы: 458
Вес: 0.90 кг.
Дата издания: 2018
Серия: Methods in Molecular Biology
Язык: English
Издание: Softcover reprint of
Иллюстрации: 70 tables, color; 70 illustrations, color; 51 illustrations, black and white; xv, 458 p. 121 illus., 70 illus. in color.
Размер: Book (Paperback Initiative)
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: This volume collects protocols and procedures utilizing cellular, tissue, and whole animal models that can be applied to the investigation of neurotrophic factors and other agents impacting on these systems. It begins with chapters on the culture of neurons and glia from the central and peripheral nervous systems, neuron-glia and glia-glia co-culture models, oligodendrocytes, and cell-based assays for the evaluation of cell vitality. This revised second edition expands to cover methodology encompassing site-specific direct labeling of neurotrophins and their receptors, angiogenesis assays, stem cells, pancreatic beta-cells, axonal transport, synapse biology, dendritic spine analysis, and brain endothelial cells. Subsequent chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides, as well as protocols describing nanofiber- and nanoparticle-based methods for brain delivery of neurotrophic agents. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Neurotrophic Factors: Methods and Protocols, Second Edition is a valuable resource for a wide audience of readers as they explore nervous system function and pathology.

Дополнительное описание: 1. Neurotrophic Factors: An Overview.- Ocular Nerve Growth Factor (NGF) and NGF Eye Drop Application as Paradigms to Investigate NGF Neuroprotective and Reparative Actions.- Culture of Rodent Cortical, Hippocampal, and Striatal Neurons.- Culture of Neonat

Neurotrophic Factors, Stephen D. Skaper