Автор: Mary Ann Asson-Batres; Cecile Rochette-Egly Название: The Biochemistry of Retinoid Signaling II ISBN: 9402409432 ISBN-13(EAN): 9789402409437 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area.
In view of the recent information explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development, and continued well-being, and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases.
Volume II is divided into nine chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.
Автор: Pohl, Ehmke Название: Retinoid Signaling Pathways,637 ISBN: 0128201444 ISBN-13(EAN): 9780128201442 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.
Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in the Methods in Enzymology series
Includes the latest information on retinoid signaling pathways
Автор: Laurent Degos; David R. Parkinson Название: Retinoids in Oncology ISBN: 3642797083 ISBN-13(EAN): 9783642797088 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Newer aspects of molecular mechanisms of retinoid effects, the cellular biology and the developmental effects of these compounds are presented together with a comprehensive description of the latest findings of retinoid pharmacology, toxicology and clinical effects in a wide range of hematological and solid malignancies.
Автор: Heinz Nau; William S. Blaner Название: Retinoids ISBN: 3642636144 ISBN-13(EAN): 9783642636141 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: with contributions by numerous experts
Автор: Christopher Redfern Название: Retinoid Protocols ISBN: 1489942440 ISBN-13(EAN): 9781489942449 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Interest in retinoic acid, the main biologically active derivative of vi- min A or retinol, increased dramatically between 1989 and 1993, following the cloning of nuclear receptors or RARs reported in 1987 (Fig.
Автор: Sun Название: Retinoids ISBN: 1617796905 ISBN-13(EAN): 9781617796906 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Exciting new biological functions are still being discovered for vitamin A derivatives, including the myriad physiological activities of retinoids. Here, experts in the field present the latest range of techniques for both in-vitro and in-vivo studies.
Автор: Heinz Nau; William S. Blaner Название: Retinoids ISBN: 3540658920 ISBN-13(EAN): 9783540658924 Издательство: Springer Рейтинг: Цена: 89303.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer.
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