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Calcium-Binding Proteins of the EF-Hand Superfamily, Claus W. Heizmann


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Автор: Claus W. Heizmann
Название:  Calcium-Binding Proteins of the EF-Hand Superfamily
ISBN: 9781493990290
Издательство: Springer
Классификация:




ISBN-10: 1493990292
Обложка/Формат: Hardcover
Страницы: 779
Вес: 1.68 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 113 tables, color; 117 illustrations, color; 58 illustrations, black and white; xix, 779 p. 175 illus., 117 illus. in color. with online files/update.
Размер: 254 x 178 x 43
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: From Basics to Medical Applications
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed volume explores protocols for studying the many facets of Ca2+-imaging, Ca2+-signaling, and Ca2+-binding along with background information on the principles and application of these techniques. The content of the book delves into 48 chapters including subjects such as data analysis and modern technologies to study calcium-binding and signaling in cells, the superfamily of calcium-binding proteins characterized by the EF-hand structural motif, as well as their use as diagnostic and prognostic biomarkers in Laboratory Medicine and novel therapeutic drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and comprehensive, Calcium-Binding Proteins of the EF-Hand Superfamily: From Basics to Medical Applications presents state-of-the-art, lab-based methods and easy-to-follow protocols for daily use, making it interesting for basic and medical researchers, cell- and molecular biologists, clinicians, clinical chemists, and the diagnostic industry.

Дополнительное описание: Using Data Mining to Explore Calmodulin Bibliography.- Deep Two-Photon Imaging In Vivo with a Red-Shifted Calcium Indicator.- High Resolution Calcium Imaging Method for Local Calcium Signaling.- Measurement of Contractility and Calcium Release in Cardiac



Ras Superfamily Small G Proteins: Biology and Mechanisms 1

Автор: Alfred Wittinghofer
Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1
ISBN: 3709118050 ISBN-13(EAN): 9783709118054
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.

Ras Superfamily Small G Proteins: Biology and Mechanisms 2

Автор: Alfred Wittinghofer
Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 2
ISBN: 3319077600 ISBN-13(EAN): 9783319077604
Издательство: Springer
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Цена: 20962.00 р.
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Описание: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

Ras Superfamily Small G Proteins: Biology and Mechanisms 1

Автор: Alfred Wittinghofer
Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 1
ISBN: 370911988X ISBN-13(EAN): 9783709119884
Издательство: Springer
Рейтинг:
Цена: 19589.00 р.
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Описание: The focus of this first volume is on the Rho and Ras subfamily of small G proteins.Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease.

Ras Superfamily Small G Proteins: Biology and Mechanisms 2

Автор: Alfred Wittinghofer
Название: Ras Superfamily Small G Proteins: Biology and Mechanisms 2
ISBN: 3319378082 ISBN-13(EAN): 9783319378084
Издательство: Springer
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Цена: 18284.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

The TNF Superfamily

Автор: Jagadeesh Bayry
Название: The TNF Superfamily
ISBN: 1493906682 ISBN-13(EAN): 9781493906680
Издательство: Springer
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Цена: 14673.00 р.
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The TNF Superfamily

Автор: Jagadeesh Bayry
Название: The TNF Superfamily
ISBN: 1493953923 ISBN-13(EAN): 9781493953929
Издательство: Springer
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Цена: 14673.00 р.
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Описание:

1. Assaying NF-kB Activation and Signaling from TNF Receptors

Zhenzhen Wu and Leslie A. Bruggeman

2. Dissecting DR3 Signaling

Yelena L. Pobezinskaya and Zhenggang Liu

3. Modulation of FceRI-Dependent Mast Cell Response by OX40L

Riccardo Sibilano, Carlo Pucillo, and Barbara Frossi

4. Analyzing the Signaling Capabilities of Soluble and Membrane TWEAK

Johannes Trebing, Josй Antonio Carmona Arana, Steffen Salzmann, and Harald Wajant

5. Regulation of Human Dendritic Cell Functions by Natural Anti-CD40 Antibodies

Sri Ramulu Elluru, Srini V Kaveri, and Jagadeesh Bayry

6. β-actin in the Signaling of Transmembrane TNF-α-Mediated Cytotoxicity

Hui Chen, Yan Leng, and Zhuoya Li

7. Investigating the Protective Role of Death Receptor 3 (DR3) in Renal Injury Using an Organ Culture Model

Rafia S. Al-Lamki

8. Analysis of TNF-Mediated Cerebral Pericyte Remodeling

Jennifer V. Welser-Alves, Amin Boroujerdi, Ulrich Tigges, and Richard Milner

9. CD137 in Chronic Graft-Versus-Host Disease

Juyang Kim, Hogng R. Cho, and Byungsuk Kwon

10. In Vitro Investigation of the Roles of the Proinflammatory Cytokines Tumor Necrosis Factor-α and Interleukin-1 in Murine Osteoclastogenesis

Joel Jules and Xu Feng

11. Evasion of TNF-α Mediated Apoptosis by Hepatitis C Virus

Hangeun Kim and Ranjit Ray

12. TNF-α Modulates TLR2-Dependent Responses During Mycobacterial Infection

Sahana Holla, Jamma Trinath, and Kithiganahalli Narayanaswamy Balaji

13. Experimental Applications of TNF-Reporter Mice with Far-Red Fluorescent Label

Yury V. Shebzukhov, Anna A. Kuchmiy, Andrei A. Kruglov, Frauke Zipp, Volker Siffrin, and Sergei A. Nedospasov

14. A Simple Solid-Phase Assay for Studying Direct Binding of Progranulin to TNFR and Progranulin Antagonism of TNF/TNFR Interactions

Tian Qingyun, Shuai Zhao, and Chuanju Liu

15. Compartment-Specific Flow Cytometry for the Analysis of TNF-Mediated Recruitment and Activation of Glomerular Leukocytes in Murine Kidneys

Volker Vielhauer

16. Determination of Soluble Tumor Necrosis Factor Receptor 2 Produced by Alternative Splicing

Xavier Romero, Juan D. Caсete, and Pablo Engel

17. Effective Expression and Purification of Bioactive Recombinant Soluble LIGHT

Isamu Tsuji, Keiji Iwamoto, and Yasushi Shintani

18. One of the TNF Superfamily Members: Bi-Functional Protein, TNFR2-Fc-IL-1ra

Bo Xie

The Superfamily of ras-Related Genes

Автор: Demetrios A. Spandidos
Название: The Superfamily of ras-Related Genes
ISBN: 146846020X ISBN-13(EAN): 9781468460209
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of a NATO ARW held in Aghia Pelagia, Crete, Greece, May 17-21, 1991

Therapeutic Targets of the TNF Superfamily

Автор: Iqbal S. Grewal
Название: Therapeutic Targets of the TNF Superfamily
ISBN: 1441927999 ISBN-13(EAN): 9781441927996
Издательство: Springer
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Цена: 26120.00 р.
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Описание: For two decades, TNF superfamily has been the most investigated area of basic medical research. This book offers a state-of-the-art account of that research, including the role of TNF superfamily members to fight cancer and autoimmune disease.

Calcium-Binding Proteins in the Human Developing Brain

Автор: N. Ulfig
Название: Calcium-Binding Proteins in the Human Developing Brain
ISBN: 3540434631 ISBN-13(EAN): 9783540434634
Издательство: Springer
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Цена: 13974.00 р.
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Описание: In the mature brain calcium ions play pivotal roles in transmembrane and intracellular transmission of signals. Thus, calcium is involved in numerous neuronal functions, and this text explores the complex processes dependent on and modulated by calcium.

Calcium Regulation by Calcium-Binding Proteins in Neurodegenerative Disorders

Автор: Claus W. Heizmann; Katharina Braun
Название: Calcium Regulation by Calcium-Binding Proteins in Neurodegenerative Disorders
ISBN: 3662216914 ISBN-13(EAN): 9783662216910
Издательство: Springer
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Цена: 6986.00 р.
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Calcium Binding Proteins

Автор: Permyakov
Название: Calcium Binding Proteins
ISBN: 0470525843 ISBN-13(EAN): 9780470525845
Издательство: Wiley
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Цена: 25019.00 р.
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Описание: Calcium Binding Proteins explains the unique and highly diverse functions of calcium in biology, which are realized by calcium binding proteins. The structures and physical characteristics of these calcium binding proteins are described, as well as their functions and general patterns of their evolution.

Novel Calcium-Binding Proteins

Автор: Claus W. Heizmann
Название: Novel Calcium-Binding Proteins
ISBN: 3642761526 ISBN-13(EAN): 9783642761522
Издательство: Springer
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Цена: 15372.00 р.
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Описание: A wide variety of hormones, neurotransmitters and growth factors exert their cellular effects by reacting first with membrane receptors resulting in an increase of intracellular calcium and the cellular response.


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