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BCL-2 Family Proteins, Evripidis Gavathiotis


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Цена: 27950.00р.
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Автор: Evripidis Gavathiotis
Название:  BCL-2 Family Proteins
ISBN: 9781493988600
Издательство: Springer
Классификация:

ISBN-10: 1493988603
Обложка/Формат: Hardcover
Страницы: 360
Вес: 0.92 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 65 tables, color; 66 illustrations, color; 30 illustrations, black and white; xi, 360 p. 96 illus., 66 illus. in color.
Размер: 254 x 178 x 22
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume explores numerous techniques for the genetic, molecular, biochemical, and structural examination of BCL-2 family proteins and their interactions. The chapters in this book cover topics such as the relevance of BCL-2 proteins in health and disease; evaluating cellular dependencies to specific BCL-2 family proteins; flow-cytometry-based methods for measuring BCL-2 proteins and mitochondrial-based cell death; measuring activity and interactions of BCL-2 family proteins in the presence of mitochondria, artificial membranes or yeast; conformational activation and oligomerization of pro-apoptotic proteins BAX and BAK leading to cytochrome c release and apoptosis; structural and biophysical studies in solution and lipid vesicles using nuclear magnetic resonance, cryo-electron microscopy, fluorescence microscopy and electron paramagnetic resonance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, BCL-2 Family Proteins: Methods and Protocols is a valuable resource to inspire and encourage novice and established scientists to further their research and make new discoveries in this exciting field.
Дополнительное описание:
Overview of BCL-2 Family Proteins and Therapeutic Potentials.- Database and Bioinformatic Analysis of BCL-2 Family Proteins and BH3-Only Proteins.- Application of Mito-Priming to Generate BCL-2 Addicted Cells.- BH3 Profiling: A Functional Assay to Me



The Coronin Family of Proteins

Автор: Christoph S. Clemen; Ludwig Eichinger; Vasily Ryba
Название: The Coronin Family of Proteins
ISBN: 1441918698 ISBN-13(EAN): 9781441918697
Издательство: Springer
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Цена: 32004.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Preparative Chromatography for Separation of Proteins

Автор: Staby
Название: Preparative Chromatography for Separation of Proteins
ISBN: 1119031109 ISBN-13(EAN): 9781119031109
Издательство: Wiley
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Цена: 25653.00 р.
Наличие на складе: Поставка под заказ.

Описание: Preparative Chromatography for Separation of Proteins addresses a wide range of the most current modeling techniques, strategies, and case studies of industrial separation of proteins and peptides to aid in the efficiency and efficacy of this broadly-used technique in the purification of biopharmaceuticals.

Acute Phase Proteins in the Acute Phase Response

Автор: Mark B. Pepys
Название: Acute Phase Proteins in the Acute Phase Response
ISBN: 1447117417 ISBN-13(EAN): 9781447117414
Издательство: Springer
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Цена: 12157.00 р.
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Описание: The discovery of C-reactive protein in the laboratory of O. T. Avery at Rockefeller University in 1929-30 was the first specific obser- vation of the acute phase plasma protein response (Tillett and Francis 1930). This was one of three contributions of fundamental importance which emerged from that laboratory, the other two being the recognition that polysaccharides could act as antigens and that DNA transmits genetic information. In the course of charac- terization of pneumococcal carbohydrate antigens, a somatic poly- saccharide common to all Rand S forms of pneumococci was identified and designated Fraction "C" (Tillet et al. 1930). Testing of sera from patients with pneumococcal infection revealed the presence of material which precipitated with the C-polysaccharide but which differed from antibody in that calcium was required for the reaction. Furthermore, the amount of reactive material was greatest when patients were acutely ill and decreased in the convalescent phase, the precise opposite of specific anti-pneumo- coccal antibodies. Subsequently, the C-reactive material was shown to be a protein and to be present in the sera of individuals who were acutely ill with other, non-pneumococcal infections and tissue damaging conditions, hence Avery coined the term "acute phase" and called the protein "acute phase protein" (Abernethy and Avery 1941; MacLeod and Avery 1941). At that time methods were too insensitive to detect C-reative protein (CRP) in sera of healthy subjects and it was considered to be a pathological product.

Computational Biophysics of Membrane Proteins

Автор: Domene Carmen
Название: Computational Biophysics of Membrane Proteins
ISBN: 1782624902 ISBN-13(EAN): 9781782624905
Издательство: Royal Society of Chemistry
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Цена: 37805.00 р.
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Описание: Exploring current themes in modern computational and membrane protein biophysics, this book is ideal for researchers in computational chemistry and computational biophysics.

Amino Acids, Peptides and Proteins: Volume 41

Автор: Ryadnov
Название: Amino Acids, Peptides and Proteins: Volume 41
ISBN: 1782625372 ISBN-13(EAN): 9781782625377
Издательство: Royal Society of Chemistry
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Цена: 66517.00 р.
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Описание: Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas for example discovery and validation of novel protein/peptide biomarkers, proteins and peptides for the diagnosis and therapy of a parasite infection and surface and interface analysis of functional proteins and peptides. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference to developments now and looking to the future.

Bone Morphogenetic Proteins: Systems Biology Regulators

Автор: Slobodan Vukicevic; Kuber Sampath
Название: Bone Morphogenetic Proteins: Systems Biology Regulators
ISBN: 3319475053 ISBN-13(EAN): 9783319475059
Издательство: Springer
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Цена: 25155.00 р.
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Proteins

Автор: John M. Walker
Название: Proteins
ISBN: 0896030628 ISBN-13(EAN): 9780896030626
Издательство: Springer
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Цена: 20263.00 р.
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Описание: Although many of the new techniques in molecular biology are relatively easy to master, it is often difficult for a researcher to obtain all the relevant information nec- sary for setting up and successfully applying a new te- nique.

Protein Bioinformatics

Автор: Bhupendra Pushkar
Название: Protein Bioinformatics
ISBN: 1774071940 ISBN-13(EAN): 9781774071946
Издательство: Mare Nostrum (Eurospan)
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Цена: 24671.00 р.
Наличие на складе: Нет в наличии.

Описание: Introduces the concept of protein bioinformatics. The book covers topics such as structure databases and biological databases, and provides a comprehensive analysis of the protein structure and further prediction in the protein structure.

Functionality of Proteins in Food

Автор: Joseph F. Zayas
Название: Functionality of Proteins in Food
ISBN: 3642638562 ISBN-13(EAN): 9783642638565
Издательство: Springer
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Цена: 20962.00 р.
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