Автор: Wu-Min Deng Название: The Drosophila Model in Cancer ISBN: 3030236315 ISBN-13(EAN): 9783030236311 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Описание: This volume includes in-depth, hands-on protocols for detecting various developmental defects in Drosophila. It provides cutting-edge methods for maintaining Drosophila under laboratory conditions to perform various experiments, and for dissecting various imaginal discs of the larvae. Further, biochemical protocols for estimating the levels of different metabolites, reactive oxygen species, and fat-sensitive pathways are discussed, and various staining and behavior techniques for fat detection are provided. The book explains how various fluorescent dyes and the comet assay can be used to identify DNA damage, and elaborates on the analysis of the eye, antennae, imaginal disc, gut and muscle damage under bright field and fluorescent microscopes. It covers the analysis of hemolymph using Giemsa staining; determining the functionality of channel proteins, eye and mechanosensory organs in adults and larvae using various behavioral assays; and metal detection and structural analysis for various tissues using SEM. In closing, it addresses the analysis of Drosophila’s eye and head via paraffin section; measurement of reactive oxygen species from various tissues via FACS; and the CRISPER technique for gene editing and analysis of micro RNA mutations.
Автор: Yamaguchi Название: Drosophila Models for Human Diseases ISBN: 9811305285 ISBN-13(EAN): 9789811305283 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
Автор: Christian Dahmann Название: Drosophila ISBN: 1617377910 ISBN-13(EAN): 9781617377914 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Drosophila is a comprehensive collection of methods and protocols for Drosophila, one of the oldest and most commonly used model organisms in modern biology. The protocols are written by the scientists who invented the methods. The text presents a diverse set of techniques that range from the basic handling of flies to more complex applications.
Автор: Jose A. Campos-Ortega; Volker Hartenstein Название: The Embryonic Development of Drosophila melanogaster ISBN: 3662224917 ISBN-13(EAN): 9783662224915 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: " . but our knowledge is so weak that no philosopher will ever be able to completely explore the nature of even a fly . " * Thomas Aquinas "In Symbolum Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophila melanogaster, conceived as a reference book on the morphology of embryonic development.
Описание: This book will discuss molecular genetic mechanisms of pattern formation, mutations in axial patterning, Genetic regulation of growth in Drosophila eye, and more.
Автор: Kevin Moses Название: Drosophila Eye Development ISBN: 3642536409 ISBN-13(EAN): 9783642536403 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow".
Автор: LinFang Wang, Honglei Wang, Margaret S. Ho Название: Drosophila Glia ISBN: 1615047999 ISBN-13(EAN): 9781615047994 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 6237.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Glia, the non-neuronal cells in the nervous systems, are both passive and active participants in diverse arrays of neuronal function. The diversity of glial cells in various animal species appears to be correlated with the complexity of brains. In the animal Drosophila melanogaster , glia are similarly categorized to their mammalian counterparts in morphology and function. Surface glia cover the outermost surface of the brain and function as a blood-brain-barrier to protect the nervous system. Cortex glia, similar to mammalian astrocytes, enwrap around the neuronal cell bodies and provide trophic support. Neuropil glia, similar to mammalian astrocytes and oligodendrocytes, are closely associated with the synapse-enriched neuropils and regulate synapse formation, synaptic function, and underlie the mechanism of circuit and behavior. This short monograph focuses on Drosophila glia, discusses the classification of different glial subtypes and their developmental origins, and provides an overview of different glial-mediated activity crucial for the development and function of the nervous system. This context serves as a general introduction to the molecular and cellular basis of glial function in normal and pathological brains.
Автор: Masamitsu Yamaguchi Название: Drosophila Models for Human Diseases ISBN: 9811344426 ISBN-13(EAN): 9789811344428 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.
Автор: W. J. Dickinson; D. T. Sullivan Название: Gene-Enzyme Systems in Drosophila ISBN: 3662219425 ISBN-13(EAN): 9783662219423 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: We are convinced that the study of enzyme behavior during development merits much attention, particularly if the work is carried out on a eukaryote that lends itself to genetic and developmental analysis.
Автор: Gerhard Martin Technau Название: Brain Development in Drosophila melanogaster ISBN: 1493950894 ISBN-13(EAN): 9781493950898 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.
Автор: Dubnau Название: Behavioral Genetics of the Fly ( Drosophila Melanogaster ) ISBN: 1107009030 ISBN-13(EAN): 9781107009035 Издательство: Cambridge Academ Рейтинг: Цена: 17899.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The common fruit fly - Drosophila melanogaster - has been the subject of genetics research since the early twentieth century. The complete genomic sequence of Drosophila was published in 2000 and it is still the model organism par excellence for the experimental study of biological phenomena and processes. It is also by far the best model for studying gene function in mammals, including humans. Presenting state-of-the-art studies on the behaviour of Drosophila, this volume discusses normal and pathological models of neurobehavioral disorders and encompasses the specialised methods that have been used, from anatomical, histological, immunohistological and neurophysiological to genomic, genetic and behavioural assays. A comprehensive and thorough reference, this volume is a valuable resource for students and researchers alike across several disciplines of life sciences, including behavioral genetics, neurogenetics, behavioral neuroscience, molecular biology, evolutionary biology and population biology.
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