Docking Screens for Drug Discovery, Walter Filgueira de Azevedo Jr.
Автор: Caffrey Название: Parasitic Helminths: Targets, Screens, Drugs and Vaccines ISBN: 3527330593 ISBN-13(EAN): 9783527330591 Издательство: Wiley Рейтинг: Цена: 12856.00 р. 18366.00-30% Наличие на складе: Есть (1 шт.) Описание: The first title dealing with drug discovery against parasitic worms (Helminths) which include many of the major human and animal parasites. The book focusses on the development of novel drugs and vaccination strategies making it attractive for academia and industry alike.
Автор: Margaret F. Docker Название: Lampreys: Biology, Conservation and Control ISBN: 940241682X ISBN-13(EAN): 9789402416824 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, published in two volumes, provides the most comprehensive review of lamprey biology since Hardisty and Potter’s “The Biology of Lampreys” published more than 30 years ago. This second volume offers a synthesis of topics related to the lamprey gonad (e.g., lamprey sex ratios, sex determination and sex differentiation, sexual maturation, and sex steroids), the artifical propagation of lampreys, post-metamorphic feeding and the evolution of alternative feeding and migratory types, the history and status of sea lamprey control in the Laurentian Great Lakes and Lake Champlain, and an overview of contributions of lamprey developmental studies for understanding vertebrate evolution.
Автор: Patwardhan, Bhushan Название: Innovative Approaches in Drug Discovery ISBN: 0128018143 ISBN-13(EAN): 9780128018149 Издательство: Elsevier Science Рейтинг: Цена: 11115.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is nowfor a renewed commitment towards expanding the repertoire of medicines.a By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences.
Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned
Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines
Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery
Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak Название: Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery ISBN: 1522501150 ISBN-13(EAN): 9781522501152 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 40128.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimal care to patients, the development of innovative pharmacological techniques has become a widely studied topic.The Handbook of Research on Molecular Docking-Based Drug Design and Discovery investigates the evolution of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting theoretical backgrounds and emergent research in the area of computer-assisted drug design, this publication is a pivotal source for professionals, researchers, medical chemists, pharmaceutical experts, and students interested in innovative practices and findings within the fields of computational chemistry and pharmaceutical sciences.
Автор: Detrich, III, H. William Название: The Zebrafish: Disease Models and Chemical Screens,105 ISBN: 0128034734 ISBN-13(EAN): 9780128034736 Издательство: Elsevier Science Рейтинг: Цена: 22570.00 р. Наличие на складе: Поставка под заказ.
Описание: The Zebrafish: Disease Models and Chemical Screens, Fourth Edition, the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome. * Covers sections on model systems and functional studies, imaging-based approaches, and emerging studies* Includes chapters written by experts in the field* Contains cutting-edge material on the topics discussed
Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak Название: Applied Case Studies and Solutions in Molecular Docking-Based Drug Design ISBN: 1522503625 ISBN-13(EAN): 9781522503620 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 28215.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimum care to patients, the development of innovative pharmacological techniques has become a widely studied topic.Applied Case Studies and Solutions in Molecular Docking-Based Drug Design is a pivotal reference source for the latest scholarly research on the progress of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting innovative research perspectives and real-world applications, this book is ideally designed for professionals, researchers, practitioners, and medical chemists actively involved in computational chemistry and pharmaceutical sciences.
Описание: Deep learning has already achieved remarkable results in many fields. Now it`s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields.
Автор: Littman Название: Translational Medicine and Drug Discovery ISBN: 0521886457 ISBN-13(EAN): 9780521886451 Издательство: Cambridge Academ Рейтинг: Цена: 13781.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. It is essential for anyone interested in translational medicine from a variety of backgrounds: university institutes, medical schools, pharmaceutical companies and drug development researchers and decision-makers.
Автор: Gabriele Proetzel; Michael V. Wiles Название: Mouse Models for Drug Discovery ISBN: 149393659X ISBN-13(EAN): 9781493936595 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Herein, these models are appliedto a wide field of disease areas, including diabetes, cardiovascular disease,skin disorders, cancer, neurodegenerative and neuromuscular diseases, retinaldisorders, as well as various behavioral models.
Автор: Seetharama D. Satyanarayanajois Название: Drug Design and Discovery ISBN: 1493958240 ISBN-13(EAN): 9781493958245 Издательство: Springer Рейтинг: Цена: 16070.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research in the pharmaceutical sciences and medicinal chemistry has taken an important new direction in the past two decades with a focus on large molecules, especially peptides and proteins, as well as DNA therapeutics. In Drug Design and Discovery: Methods and Protocols, leading experts provide an in-depth view of key protocols that are commonly used in drug discovery laboratories. Covering both classic and cutting-edge techniques, this volume explores computational docking, quantitative structure-activity relationship (QSAR), peptide synthesis, labeling of peptides and proteins with fluorescent labels, DNA-microarray, zebrafish model for drug screening, and other analytical screening and biological assays that are routinely used during the drug discovery process. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and accessible, Drug Design and Discovery: Methods and Protocols serve as a vital laboratory reference for pharmaceutical chemists, medicinal chemists, and pharmacologists as well as for molecular biologists.
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