Tim Bartels Alpha-Synuclein 9781493991235

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Автор: Tim Bartels
Название: Alpha-Synuclein
ISBN: 9781493991235
Издательство: Springer
Классификация:

Социология

Науки о жизни (медико-биологические): общие вопросы

Нейронауки

Биохимия

Белки

ISBN-10: 149399123X
Обложка/Формат: Hardcover
Страницы: 289
Вес: 0.80 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 53 tables, color; 55 illustrations, color; 11 illustrations, black and white; xii, 289 p. 66 illus., 55 illus. in color.
Размер: 254 x 178 x 18
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume provides the reader with detailed protocols that describe a variety of in vitro and in vivo techniques that study reductionist systems and human samples. The methods covered in this book explore a broad selection of topics such as functional aspects of alpha-synuclein biology, its lipid-interactions and misfolding, and functional deficits in cells and mice. Chapters also cover topics such as kinetic measurements of endocytosis and exocytosis in cultured neurons; electrochemiluminescence-based detection; yeast-based screens to target alpha-synuclein toxicity; mass-spectrometry of alpha-synuclein in rat cortical neurons; and expression and purification of untagged a-synuclein. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Alpha-Synuclein: Methods and Protocols is a valuable reference guide that aids researchers working on topics related to alpha-synuclein and its various aspects.
Дополнительное описание:

Assays for Neuronal Defects Caused by Early Formation of ?-Synuclein Inclusions in Primary Cultured Neurons.- Immunohistochemical Detection of Alpha-Synuclein in Unfixed Human Brain Tissue.- Kinetic Measurements of Endocytosis and Exocytosis in Cultu

Alpha-Synuclein, Tim Bartels