This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Tofighi Mohammad Название: Principles and Applications of Rf/Microwave in Healthcare an ISBN: 012802903X ISBN-13(EAN): 9780128029039 Издательство: Elsevier Science Рейтинг: Цена: 18022.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This reference, written by leading authorities in the field, gives basic theory, implementation details, advanced research, and applications of RF and microwave in healthcare and biosensing. It first provides a solid understanding of the fundamentals with coverage of the basics of microwave engineering and the interaction between electromagnetic waves and biomaterials. It then presents the state-of-the-art development in microwave biosensing, implantable devices -including applications of microwave technology for sensing biological tissues – and medical diagnosis, along with applications involving remote patient monitoring. this book is an ideal reference for RF and microwave engineer working on, or thinking of working on, the applications of RF and Microwave technology in medicine and biology. . Learn:. . . . The fundamentals of RF and microwave engineering in healthcare and biosensing. How to combine biological and medical aspects of the field with underlying engineering concepts. How to implement microwave biosensing for material characterization and cancer diagnosis. Applications and functioning of wireless implantable biomedical devices and microwave non-contact biomedical radars. How to combine devices, systems, and methods for new practical applications.
Автор: Ostasevicius Vytautas, Janusas Giedrius, Palevicius Arvydas Название: Biomechanical Microsystems: Design, Processing and Applications ISBN: 331985500X ISBN-13(EAN): 9783319855004 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents the most important aspects of analysis of dynamical processes taking place on the human body surface. This book also is aimed at research and development of vibrational energy harvester, which would convert ambient kinetic energy into electrical energy by means of the impact-type piezoelectric transducer.
Описание: This volume focuses on the biomechanical modeling of deformable soft tissues in the context of Computer Assisted Surgery (CAS). Discussion includes biomechanical models, estimation of in vivo mechanical behavior, real-time numerical simulations and more.
Автор: Charles Baquey; Florentina Mosora; Colin G. Caro; Название: Biomechanical Transport Processes ISBN: 1475715137 ISBN-13(EAN): 9781475715132 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of a NATO ARW held in Cargese, France, October 9-13, 1989
Автор: Luis Armentano Ricardo, Cabrera Fischer Edmundo Ignacio, Cymberknop Название: Biomechanical Modeling of the Cardiovascular System ISBN: 0750312823 ISBN-13(EAN): 9780750312820 Издательство: Неизвестно Рейтинг: Цена: 32899.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biomechanical Modeling of the Cardiovascular System brings together the challenges and experiences of academic scientists, leading engineers, industry researchers and students to enable them to analyse results of all aspects of biomechanics and biomedical engineering. It also provides a springboard to discuss the practical challenges and to propose solutions on this complex subject.
Автор: Youhong Tang; Ben Zhong Tang Название: Principles and Applications of Aggregation-Induced Emission ISBN: 3319990365 ISBN-13(EAN): 9783319990361 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the aggregation-induced emission (AIE) effect, which has opened new avenues for the development of advanced luminogenic materials in the aggregate or solid state. By enabling light emission in the practically useful solid state, AIE has the potential to significantly expand the technological applications of luminescent materials. This book addresses principles, methods, and applications of AIEs, offering a new platform for the investigation of light-emitting processes from luminogen aggregates. Applications of AIE include biomedical diagnostics, sensor materials, and optoelectronic devices, among others, and are described in detail within the book. The development of a new generation of AIEgens, a deep understanding of the AIE mechanism(s), and the exploration of advanced technological applications will enable this exciting field to develop further. Headed by the pioneering researcher who started the field, Professor Ben Zhong Tang, this book combines both principles and applications and brings together global researchers in the field to report the progress, current challenges, and potential breakthroughs that may be accomplished in the near future.Provides an authoritative account of the fundamentals, properties, and potential of AIE by the pioneer of this active, highly-researched field;Highlights technological applications of AIE spanning biomedicine, sensor materials, and optoelectronics, among others;Presents a comprehensive view on challenges in the further development of AIE and derived technologies.
Автор: Ostasevicius, Vytautas Janusas, Giedrius Palevicius, Arvydas Gaidys, Rimvydas Jurenas, Vytautas Название: Biomechanical microsystems ISBN: 3319548484 ISBN-13(EAN): 9783319548487 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents the most important aspects of analysis of dynamical processes taking place on the human body surface. This book also is aimed at research and development of vibrational energy harvester, which would convert ambient kinetic energy into electrical energy by means of the impact-type piezoelectric transducer.
Автор: Holzapfel, Gerhard A.; Ogden, Ray W. (Eds.) Название: Biomechanical Modelling at the Molecular, Cellular and Tissue Levels ISBN: 3211958738 ISBN-13(EAN): 9783211958735 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Gerhard A. Holzapfel; Ray W. Ogden Название: Biomechanical Modelling at the Molecular, Cellular and Tissue Levels ISBN: 3211999485 ISBN-13(EAN): 9783211999486 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: J.D. Humphrey: Need for a Continuum Biochemomechanical Theory of Soft Tissue and Cellular Growth and Remodeling H. Schmid and P.J. Hunter: Multi-scale Modelling of the Heart R.W. Ogden: Anisotropy and Nonlinear Elasticity in Arterial Wall Mechanics G.A. Holzapfel: Arterial Tissue in Health and Disease: Experimental Data, Collagen-based Modeling and Simulation, Including Aortic Dissection
Описание: Fall-induced hip fracture is an epidemic health risk among elderly people. This book presents an image-based multilevel modeling approach to understanding the biomechanics involved in fall-induced hip fracture. By hierarchically integrating a body-level dynamics model, a femur-level finite element model, and a local bone failure model, the biomechanics approach is able to simulate all stages in sideways falls and to incorporate all biomechanical variables affecting hip fracture.
This book is useful for clinicians to accurately evaluate fracture risk, for biomechanical engineers to virtually test hip protective devices, and for biomedical students to learn image-based biomechanical modeling techniques. This book also covers:Biomechanical viewing on bone composition, bone remodeling, and bone strengthBone imaging and information captured for constructing biomechanical modelsBone mechanical testing and mechanical properties required for biomechanical modeling
Описание: Dynamic Modeling of Musculoskeletal Motion introduces biomechanists to modern methods of modeling and analyzing dynamic biomechanical systems in three dimensions. Using vector kinematics, the reader is taught a systematic method which significantly reduces the complexity of working with multiple, moving limb segments in three dimensions.
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