Описание: Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. . The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. . In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics.
Автор: Ozbolat, Ibrahim Tarik, Название: 3D Bioprinting : ISBN: 0128030100 ISBN-13(EAN): 9780128030103 Издательство: Elsevier Science Рейтинг: Цена: 18528.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"3D Bioprinting: Fundamentals, Principles and Applications" provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives.
Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics. Describes all aspects of the bioprinting process, from bioink processing through design for bioprinting, bioprinting techniques, bioprinter technologies, organ printing, applications, and future trendsProvides a detailed description of each bioprinting technique with an in-depth understanding of its process modeling, underlying physics and characteristics, suitable bioink and cell types printed, and major accomplishments achieved thus farExplains organ printing technology in detail with a step-by-step roadmap for the 3D bioprinting of organs from isolating stem cells to the post-transplantation of organsPresents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics
Описание: This book provides current and emerging developments in bioprinting with respect to bioprinting technologies, bioinks, applications, and regulatory pathways. Topics covered include 3D bioprinting technologies, materials such as bioinks and bioink design, applications of bioprinting complex tissues, tissue and disease models, vasculature, and musculoskeletal tissue. The final chapter is devoted to clinical applications of bioprinting, including the safety, ethical, and regulatory aspects. This book serves as a go-to reference on bioprinting and is ideal for students, researchers and professionals, including those in academia, government, the medical industry, and healthcare.
Автор: Mozafari, Masoud Название: Handbook of Tissue Engineering Scaffolds ISBN: 0081025637 ISBN-13(EAN): 9780081025635 Издательство: Elsevier Science Рейтинг: Цена: 47161.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Handbook of Tissue Engineering Scaffolds: Volume One, provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems.
Dedicated to the specialist topic of composite scaffolds, featuring all human body systems
Covers basic fundamentals and advanced clinical applications
Includes up-to-date information on preparation methodology and characterization techniques
Описание: Addresses the principles, methods and applications of biodegradable polymer based scaffolds for bone tissue engineering. In this title, the general principle of bone tissue engineering is reviewed and the traditional and novel scaffolding materials, their properties and scaffold fabrication techniques are explored.
Автор: Mozafari, Masoud Название: Handbook of Tissue Engineering Scaffolds ISBN: 0081025610 ISBN-13(EAN): 9780081025611 Издательство: Elsevier Science Рейтинг: Цена: 47161.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Handbook of Tissue Engineering Scaffolds: Volume Two provides a comprehensive and authoritative review on recent advancements in the application and use of composite scaffolds in tissue engineering. Chapters focus on specific tissue/organ (mostly on the structure and anatomy), the materials used for treatment, natural composite scaffolds, synthetic composite scaffolds, fabrication techniques, innovative materials and approaches for scaffolds preparation, host response to the scaffolds, challenges and future perspectives, and more. Bringing all the information together in one major reference, the authors systematically review and summarize recent research findings, thus providing an in-depth understanding of scaffold use in different body systems.
Dedicated to the specialist topic of composite scaffolds, featuring all human body systems
Covers basic fundamentals and advanced clinical applications
Includes up-to-date information on preparation methodology and characterization techniques
Highlights clinical data and case studies
Автор: Deng, Ying Название: Functional 3D Tissue Engineering Scaffolds ISBN: 0081009798 ISBN-13(EAN): 9780081009796 Издательство: Elsevier Science Рейтинг: Цена: 36213.00 р. Наличие на складе: Поставка под заказ.
Описание:
In order to grow replacement tissues, 3D scaffolds are widely used as a template for tissue engineering and regeneration. These scaffolds, which are typically 'seeded' with cells, support the growth of new tissues. However, in order to achieve successful tissue growth, the scaffold must meet specific requirements and are often 'functionalized' to accentuate particular properties. Functional 3D tissue engineering scaffolds: materials, technologies, and applications, is a comprehensive review of functional 3D scaffolds, providing information on the fundamentals, technologies, and applications.
Part 1 focuses on the fundamentals of 3D tissue scaffolds, examining information on materials, properties, and trends. Part 2 discusses a wide range of conventional technologies for engineering functional 3D scaffolds, leading the way to a discussion on CAD and advanced technologies for functional 3D scaffold engineering. Chapters in part 3 study methods for functionalizing scaffolds to support a variety of in vivo functions whilst the final set of chapters provides an important review of the most significant applications of functional 3D scaffolds within tissue engineering.
This book is a valuable resource for biomaterial scientists and biomedical engineers in academia and industry, with interests in tissue engineering and regenerative medicine.
Описание: This book examines the manipulation of polymer chemical structure and composition to tune scaffold physical properties and optimization of scaffold 3D architecture by a smart use of both fabrication techniques.
Автор: Meital Zilberman Название: Active Implants and Scaffolds for Tissue Regeneration ISBN: 3642268129 ISBN-13(EAN): 9783642268120 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Active implants are actually drug or protein-eluting implants that induce healing effects, in addition to their regular task, such as support. This book gives a broad overview of biomaterial platforms used as basic elements of drug-eluting implants.
Описание: This book addresses important biomaterials which are commonly used to fabricate scaffolds and it describes two major protocols employed in scaffold fabrication. Tissue engineering or regenerative medicine aims at restoring ex-novo tissues and organs whose functionality has been compromised as a consequence of diseases or traumatic events. The innovative concept underlying tissue engineering is the use of autologous cells, obtained from a biopsy of the patient. Cells are seeded on a porous scaffold which has the role of supporting and guiding cells towards the development of tissue-like structures as well as providing a platform for the delivery under controlled condition of growth factor release, etc. The successful manufacture of scaffolds for tissue engineering applications is crucial. In this book, these biomaterials are discussed. The book also covers illustrated examples, structure and properties of scaffolds, cellular interactions and drug delivery.
Автор: P Tomlins Название: Characterisation and Design of Tissue Scaffolds ISBN: 1782420878 ISBN-13(EAN): 9781782420873 Издательство: Elsevier Science Рейтинг: Цена: 30318.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues.
Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers.
Описание: This book presents a comprehensive study on microextrusion-based 3D bioprinting technologies for bioinks with various crosslinking mechanisms, chiefly focusing on the bioprinting process and bioink properties to provide readers with a better understanding of this state-of-the-art technology. Further, it summarizes a number of general criteria and research routes for microextrusion-based 3D bioprinting using three experimental studies based on shear-thinning, thermo-sensitive and non-viscous hydrogel bioinks. The book also presents sample applications in the areas of stem cells and cell matrix interaction. The book highlights pioneering results in the development of bioprinting technologies and bioinks, which were published in high-quality journals such as Advanced Materials, Biofabrication and ACS Biomaterials Science & Engineering. These include an in-situ crosslinking strategy that overcomes the viscosity limits for bioinks, which is virtually impossible using conventional strategies, and can be generalized for other bioink formulations.
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