Описание: This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies.
Автор: Bernd Nilius; Veit Flockerzi Название: Mammalian Transient Receptor Potential (TRP) Cation Channels ISBN: 3319051601 ISBN-13(EAN): 9783319051604 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
Автор: Bernd Nilius; Veit Flockerzi Название: Mammalian Transient Receptor Potential (TRP) Cation Channels ISBN: 364254214X ISBN-13(EAN): 9783642542145 Издательство: Springer Рейтинг: Цена: 53106.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
Автор: Arpad Szallasi; Tam?s B?r? Название: TRP Channels in Drug Discovery ISBN: 1493962817 ISBN-13(EAN): 9781493962815 Издательство: Springer Рейтинг: Цена: 25853.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With state-of-the-art reviews of the most interesting TRP channels, from TRPA1 to TRPV4, this volume contains key tips on implementation as well as clear and focused laboratory-ready protocols on TRP channels and disorders of airways and the GU tract.
Автор: Jackson, William F. Название: Ion Channels And Calcium Signaling In The Microcirculation,85 ISBN: 0128200901 ISBN-13(EAN): 9780128200902 Издательство: Elsevier Science Рейтинг: Цена: 25265.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more.
Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.
Описание: This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels.
Автор: A. Pullman; Joshua Jortner Название: Transport Through Membranes: Carriers, Channels and Pumps ISBN: 9027728313 ISBN-13(EAN): 9789027728319 Издательство: Springer Рейтинг: Цена: 54504.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the twenty-first Jerusalem Symposium on Quantum Chemistry and Biochemistry, held in Jerusalem, Israel, May 16-19, 1988
Автор: Anne H. Delcour Название: Electrophysiology of Unconventional Channels and Pores ISBN: 3319372351 ISBN-13(EAN): 9783319372358 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.
Автор: Show-Ling Shyng; Francis I. Valiyaveetil; Matt Who Название: Potassium Channels ISBN: 1493973614 ISBN-13(EAN): 9781493973613 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides readers with the latest techniques and approaches used to study K+ channels.
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