Автор: Christopher J. Barker Название: Inositol Phosphates and Lipids ISBN: 1617796891 ISBN-13(EAN): 9781617796890 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text introduces the basic methodological tools to measure inositol lipids and phosphates and also describes new approaches that have become available in the last ten years, including g RNA-silencing and the protocols involving inositol pyrophosphates.
Описание: The heterogeneity of topics...is very ambitious, and the result is, overall, successful because of the high quality of the individual contributions....highly recommended.' -American Scientist, from a review of a previous volume Volume 26 examines the emerging areas of signal transduction based on myoinositol phosphates and Ca2+ while focusing on plant and animal responses. Chapters explore synthesis, separation, and identification of different inositol phosphates.
Автор: Gregory J. Miller Название: Inositol Phosphates ISBN: 1071601695 ISBN-13(EAN): 9781071601693 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Поставка под заказ.
Описание: Chapters focus on methods to study enzymes that modify inositol signals, chemical biology of inositol phosphates, and methods to synthesize and purify inositol phosphates and their analogs.
Автор: Nanda, Sitansu Sekhar ; Singh, Jitendra Pal ; Gaut Название: Advanced Synthesis and Medical Applications of Calcium Phosphates ISBN: 1032419636 ISBN-13(EAN): 9781032419633 Издательство: Taylor&Francis Рейтинг: Цена: 25265.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Lorenzo A. Pinna; Patricia T.W. Cohen Название: Inhibitors of Protein Kinases and Protein Phosphates ISBN: 3642422063 ISBN-13(EAN): 9783642422065 Издательство: Springer Рейтинг: Цена: 69876.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.
Автор: John E. Bleasdale; Joseph Eichberg; George Hause Название: Inositol and Phosphoinositides ISBN: 1461296021 ISBN-13(EAN): 9781461296027 Издательство: Springer Рейтинг: Цена: 21661.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Chilton Conference on Inositol and Phosphoinositides, held on January 9-11, 1984 at Southwestern Medical School, University of Texas Health Science Center, Dallas, Texas, was the third in a series of conferences on cyclitols and phosphoinositides.
Автор: Jessen Henning Jacob Название: Phosphate Labeling and Sensing in Chemical Biology ISBN: 3319868462 ISBN-13(EAN): 9783319868462 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Автор: Alice P?bay; Kursad Turksen Название: Sphingosine-1-Phosphate ISBN: 1493984780 ISBN-13(EAN): 9781493984787 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This fully updated edition explores methods involving sphingosine-1-phosphate (S1P), a bioactive lysophospholipid which has become the focus of much research interest as it has widespread developmental and physio-pathological actions, controlling events within the nervous, reproductive, gastrointestinal, vascular, respiratory, and immune systems, in addition to having a prominent role in cancer, early mammalian embryogenesis, and stem cells. Here, worldwide experts in the S1P field describe in-depth techniques in an array of cell types and with various physiological applications, showcasing the important effects of S1P in development and in physiopathology. As a volume in the Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the relevant materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and timely, Sphingosine-1-Phosphate: Methods and Protocols, Second Edition is another key resource for scientists working in this fast-moving and dynamic field.
Автор: Henning Jacob Jessen Название: Phosphate Labeling and Sensing in Chemical Biology ISBN: 3319603566 ISBN-13(EAN): 9783319603568 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes.
Автор: Sirover, Michael A. (lewis Katz School Of Medicine, Temple University, Philadelphia, Pa, Usa) Название: Glyceraldehyde-3-phosphate dehydrogenase (gapdh) ISBN: 012809852X ISBN-13(EAN): 9780128098523 Издательство: Elsevier Science Рейтинг: Цена: 15993.00 р. Наличие на складе: Поставка под заказ.
Описание:
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity.
This protein's diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion.
This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the biochemistry of GAPDH in health and disease.
Автор: Alice P?bay; Kursad Turksen Название: Sphingosine-1-Phosphate ISBN: 1493974122 ISBN-13(EAN): 9781493974122 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Measuring Sphingosine-1-Phosphate/Protein Interactions with the Kinetic Exclusion Assay
Jonathan K. Fleming and Jonathan M. Wojciak
2. An Improved Isoform-Selective Assay for Sphingosine Kinase 1 Activity
Melissa R. Pitman, Lorena T. Davies, and Stuart M. Pitson
3. Methods for Analyzing Sphingosine-1-Phosphate Signaling in Human and Mouse Primary Mast Cells
Alena P. Chumanevich, Piper A. Wedman, and Carole A. Oskeritzian
4. Measurement of Lysophosphatidic Acid and Sphingosine-1-Phosphate by Liquid Chromatography-Coupled Electrospray Ionization Tandem Mass Spectrometry
Maria P. Kraemer, Suchismita Halder, Susan S. Smyth, and Andrew J. Morris
5. Immunohistochemical Detection of Sphingosine-1-Phosphate and Sphingosine Kinase-1 in Human Tissue Samples and Cell Lines
Gary M. Reynolds, Barbara Visentin, and Roger Sabbadini
6. A Clean-Up Method for Mass Spectrometric Analysis of Sphingosine-1-Phosphate in Blood and Solid Tissues Using a Phosphate Capture Molecule
Jun-ichi Morishige, Ryouhei Yamashita, Tamotsu Tanaka, and Kiyoshi Satouchi
7. A Rapid Fluorescence Assay for Measuring Sphingosine-1-Phosphate Transporter Activity in Erythrocytes
Naoki Kobayashi and Tsuyoshi Nishi
8. Analysis of S1P Receptor Expression by Uterine Immune Cells Using Standardized Multi-Parametric Flow Cytometry
Jianhong Zhang, Annie Bang, and Stephen J. Lye
9. S1P Synergizes with Wall Shear Stress and Other Angiogenic Factors to Induce Endothelial Cell Sprouting Responses
Camille Duran, Roland Kaunas, and Kayla Bayless
10. In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate
Melina G. Castro, Ludmila E. Campos, Yamila I. Rodriguez, and Sergio E. Alvarez
11. Maintenance of Human Embryonic Stem Cells by Sphingosine-1-Phosphate and Platelet-Derived Growth Factor
Raymond C.B. Wong, Martin F. Pera, and Alice Pйbay
12. Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors
Phillip Callihan, Mohammed Alqinyah, and Shelley B. Hooks
13. Ceramide and S1P Signaling in Embryonic Stem Cell Differentiation
Guanghu Wang, Stefka D. Spassieva, and Erhard Bieberich
14. 3D Stacked Construct: A Novel Substitute for Corneal Tissue Engineering
Shrestha Priyadarsini, Sarah E. Nicholas, and Dimitrios Karamichos
Автор: Alice P?bay; Kursad Turksen Название: Sphingosine-1-Phosphate ISBN: 1493959638 ISBN-13(EAN): 9781493959631 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) volume describes in-depth techniques in an array of cell types and with various physiological applications, showcasing the important effects of S1P in development and in physiopathology. Includes troubleshooting tips and more.
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