Metabolic Flux Analysis in Eukaryotic Cells, Deepak Nagrath

Автор: Thomas M. Koval
Название: Stress-Inducible Processes in Higher Eukaryotic Cells
ISBN: 030645677X ISBN-13(EAN): 9780306456770
Издательство: Springer
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Описание: Koval provides an interdisciplinary forum for the diverse studies involved in the stress biology of eukaryotic cells. Readers gain access to the most recent information available for eukaryotic systems ranging from plants to humans.

Автор: Tobias A. Oelschlaeger; J?rg H. Hacker
Название: Bacterial Invasion into Eukaryotic Cells
ISBN: 1441933301 ISBN-13(EAN): 9781441933300
Издательство: Springer
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Описание: Strategies of Bacterial Interaction with Eukaryotic Cells *Tobias A. Oelschlaeger and Jorg Hacker 1. BENEFICIAL BACTERIAL-HOST INTERACTIONS Already during birth and soon thereafter mammals are colonized by bacte- ria belonging to the resident microbial flora. Cutaneous and mucosal sur- faces and the gastrointestinal tract are the areas which become colonized. These indigenous or autochthonous bacteria have a variety of beneficial effects on their hosts. They play a protective role by bacterial antagonism in fighting infections (Hoszowski and Truszczynski, 1997; Hentges, 1979). Pro- duction of vitamin K is another essential contribution of the resident microbial flora to the health of the host (Hill, 1997). Even more important, studies with germ-free animals demonstrated the involvement of the microbial flora on the development of the immune system. Such animals have underdeveloped and relatively undifferentiated lymphoid tissues and low concentrations of serum immune globulins ( Cebra et at., 1998). They TOBIAS A. OELSCHLAEGER and JORG HACKER Institut filr Molekulare lnfektionsbiologie, Universitiit Wiirzburg, 97070 Wiirzburg, Germany. *Corresponding author; Phone: (0)931-312150; FAX: (0)931-312578; E-mail: t.oelschlaeger@mail.uni-wuerzburg.de xxix Tobias A. Oelschlaeger and Jorg Hacker also show defects in specific immune responsiveness and in nonspecific resistance induced by endotoxin, which may account for their lowered resis- tance. A more typical example of symbiotic interaction of bacteria with a host are bacteria like Ruminococcus in the gut of ruminants, essential for degradation of cellulose (Hobson, 1988). The closest benefical bacterial-host interactions are those of intracellular symbiotic bacteria and their host cells.

Автор: Joseph M. Tager; Angelo Azzi; Sergio Papa; Ferrucc
Название: Organelles in Eukaryotic Cells
ISBN: 1461278597 ISBN-13(EAN): 9781461278597
Издательство: Springer
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Описание: Every year, the Federation of European Biochemical Societies sponsors a series of Advanced Courses designed to acquaint postgraduate students and young postdoctoral fellows with theoretical and practical aspects of topics of current interest in biochemistry, particularly within areas in which significant advances are being made.

Автор: Richard W Compans
Название: Protein Traffic in Eukaryotic Cells
ISBN: 364276391X ISBN-13(EAN): 9783642763915
Издательство: Springer
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Описание: Understanding the mechanisms involved in intracellular movement and localization of proteins is a central issue in cell biology. In several chapters, particular attention is given to studies with viruses that are assembled by budding at specific membrane sites within the cell or at the cell surface;

Автор: Joris Winderickx; Peter M. Taylor
Название: Nutrient-Induced Responses in Eukaryotic Cells
ISBN: 3662308223 ISBN-13(EAN): 9783662308226
Издательство: Springer
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Описание: Cells of all living organisms have the ability to respond to altered nutritional conditions. They have developed mechanisms to sense nutrient availability and to produce appropriate responses, which involve changes in gene expression and the production or degradation of certain enzymes and other proteins. In recent years, the understanding of nutrient-induced signal transduction has greatly advanced and the emerging picture is that nutrient signalling mechanisms evolved early in evolution. This book provides a detailed presentation and comparison of the key nutritional regulatory mechanisms in lower as well as higher eukaryotes, written by recognised experts in this expanding field.

Автор: Tobias A. Oelschlaeger; J?rg H. Hacker
Название: Bacterial Invasion into Eukaryotic Cells
ISBN: 0306462907 ISBN-13(EAN): 9780306462900
Издательство: Springer
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Описание: This latest volume in the "Subcellular Biochemistry" series is an attempt to give an in-depth overview of the field of bacterial cell invasion. Late-20th century knowledge about all well-studied bacteria with the ability to invade eukaryotic cells is brought together.

Автор: Wolfgang Hennig
Название: Structure and Function of Eukaryotic Chromosomes
ISBN: 3662224380 ISBN-13(EAN): 9783662224380
Издательство: Springer
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Описание: This book presents an overview of various aspects of chromosome research, written by leading experts of the respective fields, combining classic and recent molecular biological results. The variety and comprehensiveness make it a handbook of chromosome research for all scientists, teachers and graduate students interested in this field. Dieses Buch fa?t die unterschiedlichen Aspekte der Chromosomenforschung in Beitr?gen von f?hrenden Wissenschaftlern zusammen, wobei die klassischen Erkenntnisse mit neuesten Forschungsdaten zu einem umfassenden ?berblick ?ber das Gebiet kombiniert werden.

Автор: John LaCava; ?t?p?nka Va???ov?
Название: The Eukaryotic RNA Exosome
ISBN: 1493998218 ISBN-13(EAN): 9781493998210
Издательство: Springer
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Описание: This volume provides a cross-section of RNA exosome research protocols, applied to a diversity of model organisms. Chapters guide readers through methods that e.g. delineate eukaryotic exosomes’ origins in prokaryotes, probe its RNA substrates, adapter complexes and macromolecular interaction of networks, and establish critical structural-function relationships. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Eukaryotic RNA Exosome: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Автор: G?sp?r J?kely
Название: Eukaryotic Membranes and Cytoskeleton
ISBN: 1441925414 ISBN-13(EAN): 9781441925411
Издательство: Springer
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Описание: This book discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective. Many of the chapters present original research data from comparative genomic surveys.

Автор: Ronald T. Acton
Название: Eukaryotic Cell Cultures
ISBN: 1461593786 ISBN-13(EAN): 9781461593782
Издательство: Springer
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Описание: The Second International Cell Culture Congress was structured as was the First Congress to bring together scientists from academia and industry to discuss the use of cell culture in support of bioscience.

Автор: H. Bielka; H. Bielka; U. A. Bommer; H. Welfle; F.
Название: The Eukaryotic Ribosome
ISBN: 364268274X ISBN-13(EAN): 9783642682742
Издательство: Springer
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Описание: Contents References 11 II. A short historical survey 13 References 16 III. Ribosomes within the cell 20 1. Proportion of ribosomes in tissues 21 2. Free and membrane-bound ribo- mes 22 3. Ribosomes in nucleoli 26 4. Structure of polysomes in the cell 26 5. Ribosomal crystals 33 6. References 33 IV. Some general properties of ribosomes 41 1. Physical characteristics 41 2. Chemical characteristics 43 3. References 44 V. Morphology of ribosomes and poly- somes 47 1. Electron microscopy 47 a) The small ribosomal subunit 48 b) The large ribosomal subunit 48 c) The monomeric ribosome 52 d) Three-dimensional models 54 e) Polysomes 55 2. Small-angle X-ray scattering 55 a) The monomeric ribosome 56 b) Polysomes 57 3. References 57 VI. Chemical components 61 1. Ribosomal proteins 61 a) Electrophoretic separation and num- ber 61 b) Preparation of single ribosomal pro- teins 67 c) Molecular weights 68 d) Amino acid composition and amino acid sequences 71 e) Stoichiometry 71 f) Posttranslational modifications 72 g) Comparison of ribosomal proteins of different tissues 73 h) Species specificities and evolution 74 i) Ribosomal proteins of mitochondria and chloroplasts 75 k) Ribosomal mutants with altered pro- teins 75 5 3. Formation of preribosomal 2. Phosphorylation of ribosomal prote- particles 139 ins 76 4. References 141 a) In vitro phosphorylation and de- phosphorylation 76 VIII. Dissociation - reassociation processes b) In vivo phosphorylation 77 of ribosomal particles 151 c) Phosphorylation of ribosomal pro- tein S 6 78 1.

Автор: A. De Recondo
Название: New Approaches in Eukaryotic DNA Replication
ISBN: 1468443992 ISBN-13(EAN): 9781468443998
Издательство: Springer
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Описание: DNA replication in eukaryotes is an important field, particular- ly because of its direct impact on the study of cancer.