Автор: Jos?-Luis Barredo; Ignacio Herr?iz Название: Microbial Steroids ISBN: 1493971824 ISBN-13(EAN): 9781493971824 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface... Table of Contents... Contributing Authors...
1. Steroid Bioconversions Marina V. Donova 2. Chemical Pathways of Corticosteroids, Industrial Synthesis from Sapogenins Ignacio Herrбiz 3. Genome Sequencing of Steroid Producing Bacteria with Illumina Technology Victoria Y. Shtratnikova, Mikhail I. Schelkunov, and marina V. Donova 4. Genome Sequencing of Steroid Producing Bacteria using Ion Torrent Technology and a Reference Genome Alberto Sola-Landa, Antonio Rodrнguez-Garcнa, Carlos Barreiro, and Rosario Pйrez-Redondo 5. RNA-Seq-Based Comparative Transcriptomics: RNA Preparation and Bioinformatics Antonio Rodrнguez-Garcнa, Alberto Sola-Landa, and Carlos Barreiro 6. Intra- and Extra-Cellular Proteome Analyses of Steroid-Producer Mycobacteria Carlos Barreiro, Alejandro Morales, Inйs Vбzquez-Iglesias, and Alberto Sola-Landa 7. Genetic Techniques for Manipulation of the Phytosterol Biotransformation Strain Mycobacteriumneoaurum NRRL B-3805 Jessica K. Loraine and Margaret C. M. Smith 8. Identification and Characterization of the genes and Enzymes Belonging to the Bile Acid Catabolic Pathway in Pseudomonas Josй M. Luengo and Elias R. Olivera 9. Selection of Biodegrading Phytosterol Strains Marнa-Angйlica Mondaca, Maricel Vidal, Soledad Chamorro, and Gladys Vidal 10. Stigmasterol Removal by an Aerobic Treatment System Soledad Chamorro, Claudia Xavier, Vнctor Hernбndez, Josй Becerra, and Gladys Vidal 11. Production and Biotransformation of Phytosterol Microdispersions to Produce 4-Androstene-3, 17-Dione Rodrigo A. Mancilla, Roberto Pavez-Dнaz, and Andrea Muсoz-Orrego 12. Β-Sitosterol Bioconversion to Androstenedione in Microtiter Plates Marco P.C. Marques and Pedro Fernandez 13. Bioconversion of Phytosterols into Androstenedione by Mycobacterium Kjell D. Josefsen, Anna Nordborg, and Hеvard Sletta 14. Scale-Up of Phytosterols Bioconversion into Androstenedione Sonia Martнnez-Cбmara, Esther Bahнllo, Josй-Luis Barredo, and Marta Rodrнguez-Sбiz 15. Bioconversion of Phytosterols into Androstadienedione by Mycobacterium smegmatis CECT 8331 Julia Garcнa-Fernбndez, Igor Martнnez, Lorena Fernбndez-Cabezуn, Carmen Felpeto-Santero, Josй-Luis Garcнa, and Beatriz Galбn 16. Process for Biotransformation of Androsta-4-ene-3, 17-Dione (4-AD) to Androsta-1, 4-Diene-3, 17-Dione (ADD) Surya Prakash and Abhay Bajaj 17. Laboratory-Scale Hydroxylation of Steroids by P450BM3 Variants Sabrina Hoebenreich, Martin Spinck, and Nathalie Nett 18. Obtaining of 11α-Hydroxy and Rost-4-ene-3, 17-Dione from Natural Sterols Dmitry Dovbnya, Sergey Khomutov, Vyacheslav Kollerov, Marina Donova 19. Steroid 11-Alfa-Hydroxylation by the Fungi Aspergillus nidulans and Aspergillus ochraceus Lidia Ortega-de los Rнos, Josй M. Luengo, and Josй M. Fernбndez-Caсуn 20. Biotransformation of DHEA into 7α, 15α-diOH-DHEA Hui Li, Jin Sun, and Zhenghong Xu 21. Stabilization of Enzymes by Using Thermophiles Ana-Luisa Ribeiro, Mercedes Sбnchez, Aurelio Hidalgo, and Josй Berenguer
22. Biocatalysis of Steroids with Mycobacterium Sp. in Aqueous and Organic Media Carla C. C. R. de Carvalho and Pedro Fernandes
23. Downstream Process Synthesis for Microbial Steroids Fabian B. Thygs and Juliane Merz 24. Analysis of Intermediates of Steroid Transformations in Resting Cells by Thin Layer Chromatography (TLC) Govinda Guevara, Juliбn Perera, and Juana-Marнa Navarro-Llorens
Автор: Bradley Evans Название: Nonribosomal Peptide and Polyketide Biosynthesis ISBN: 1493980343 ISBN-13(EAN): 9781493980345 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I: Background and Overview
1. Structural Biology of Nonribosomal Peptide Synthetases
Bradley R. Miller and Andrew M. Gulick
2. The Assembly Line Enzymology of Polyketide Biosynthesis
Marisa Till and Paul R. Race
Part II: In Vitro Methods
3. Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay
Benjamin P. Duckworth, Daniel J. Wilson, and Courtney C. Aldrich
4. Affinity Purification Method for the Identification of Nonribosomal Peptide Biosynthetic Enzymes Using a Synthetic Probe for Adenylation Domains
Fumihiro Ishikawa and Hideaki Kakeya
5. Colorimetric Detection of the Adenylation Activity in Nonribosomal Peptide Synthetases
6. Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis
Clara Brieke, Veronika Kratzig, Madeleine Peschke, and Max J. Cryle
7. Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro
Ralph A. Cacho and Yi Tang
8. The Continuing Development of E. coli as a Heterologous Host for Complex Natural Product Biosynthesis
Haoran Zhang, Lei Fang, Marcia S. Osburne, and Blaine A. Pfeifer
9. Screening for Expressed Non
ribosomal Peptide Synthetases and Polyketide Synthases Using LC‒MS/MS-Based Proteomics
Yunqiu Chen, Ryan A. McClure, and Neil L. Kelleher
10. Enhancing Nonribosomal Peptide Biosynthesis in Filamentous Fungi
Alexandra A. Soukup, Nancy P. Keller, and Philipp Wiemann
11. In Situ Analysis of Bacterial Lipopeptide Antibiotics by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
Delphine Debois, Marc Ongena, Hйlиne Cawoy, and Edwin De Pauw
Описание: Introduction.- Materials and Methods.- Substrate Specificity of Ketosynthase Domains Part I: β-Branched Acyl Chains.- Substrate Specificity of Ketosynthase Domains Part II: Amino Acid-Containing Acyl Chains.- Synthesis of Acyl-Acyl Carrier Proteins and their use in Studying Polyketide Synthase Enzymology.- Substrate Specificity of Ketosynthase Domains Part III: Elongation-Based Substrate Specificity.
Автор: Bradley Evans Название: Nonribosomal Peptide and Polyketide Biosynthesis ISBN: 1493933736 ISBN-13(EAN): 9781493933730 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This volume presents an overview of nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) structure and function. It then continues with methods for the analysis of these pathways including conventional enzymological assays, contemporary mass spectrometric analysis techniques, specialized molecular biological approaches applicable to NRPSs and PKSs, and small molecule analysis tools tailored to this very special class of natural products, and concludes by examining bioinformatics tools for the analysis of these enzymes, pathways, and molecules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols serves as a valuable reference for those experienced in studying NRPS and PKS enzymes, pathways, and natural products as well as a gateway for those just entering the field.
Автор: Hoffman Janet Название: Steroids: Therapies and Applications ISBN: 1632423820 ISBN-13(EAN): 9781632423825 Издательство: Неизвестно Цена: 18346.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Mason Dwyane Название: Recent Progress in Steroids Research ISBN: 163242827X ISBN-13(EAN): 9781632428271 Издательство: Неизвестно Рейтинг: Цена: 24140.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: M. Capek; O. Hanc; M. Tadra Название: Microbial Transformations of Steroids ISBN: 9401176051 ISBN-13(EAN): 9789401176057 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Fundamental studies of steroid compounds have begun approximately thirty years ago with the solution of structures of cholesterol and bile acids. This field has been receiving more attention when the structures of the principal steroid hormones, aglycones of heart glycosides, sapogenins, steroid alkaloids, toad poisons have been established. An intensive interest in these derivatives of cyc1opentanoperhydrophe nanthrene was determined especially by practical viewpoints, notably by attempts to prepare by synthetical economical procedures a series of steroid hormones and their biologically active derivatives, further by theoretical viewpoints. Biochemistry of steroids was developing in its beginnings by studies of meta bolites of steroid hormones in animal organism and soon has brought a number of practical results that could be used also in medical diagnostics. Considerably later, the metabolism of steroid compounds was followed also in microorganisms, again in connection with the practical problem to aid to economical syntheses of some steroid hormones. Two names are of primary importance for the pioneer works in microbial transformations of steroids, that of the Italian worker L. MAMOLI who first realized the microbial biosynthesis of testosterone from dehydroepiandro sterone, and of the American chemist and microbiologist D. H. PETERSON, who has contributed by his fundamental experiments in microbial hydroxylation of steroids to the position eleven, especially to the synthesis of cortisone. Microbial transforma tions of steroids nowadays offer a valuable tool in the preparation of series otherwise difficultly accessible steroid compounds.
Автор: Mason Dwyane Название: Handbook of Steroids ISBN: 1632417898 ISBN-13(EAN): 9781632417893 Издательство: Неизвестно Рейтинг: Цена: 24944.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: A. T. Gregoire Название: Contraceptive Steroids ISBN: 1461293138 ISBN-13(EAN): 9781461293132 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: One of the United States Food and Drug Administration`s most difficult tasks is the assessment of risk-benefit ratios for a broad spectrum of therapeutic and prophylactic drugs.
Автор: Hoffman Janet Название: Encyclopedia of Sex Steroids ISBN: 1632421747 ISBN-13(EAN): 9781632421746 Издательство: Неизвестно Цена: 23979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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