This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Laurence Brunton, Bruce Chabner Название: Goodman And Gilman`s Pharmacological Basis Of Therapeutics 12 ed ISBN: 0071624422 ISBN-13(EAN): 9780071624428 Издательство: McGraw-Hill Рейтинг: Цена: 17503.00 р. 25004.00-30% Наличие на складе: Есть (1 шт.) Описание: A medical text that represents accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. It helps thousands of practitioners and students to an understanding of the drugs essential to preventing, diagnosing, and treating disease.
Автор: W. Holmes Название: Pharmacological Control of Lipid Metabolism ISBN: 1468475495 ISBN-13(EAN): 9781468475494 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Each meeting has introduced or developed some new concepts in the areas of lipid metabolism and drugs. Principal among the many new concepts discussed were lipoprotein synthesis and metabolism, apoprotein structure and function, whole body metabolism of cholesterol, and aspects of myocardial and aortic metabolism.
Описание: Das Buch enthalt Kapitel uber: M. Azria, Basel, CH: "Calcitonin - Physiologische und Pharmakologische Aspekte"U. Niemeyer, J. Engel, P. Hilgard, M. Peukert, J. Pohl, H. Sindermann, Bielefeld, FRG: "Mafosfamid - Ein Derivat des " "4-Hydroxycyclophosphamids"S. Grunwald, G.P. Pfeifer, Frankfurt, FRG: "Enzymatische DNA Methylierung"
Описание: Underscores the complexity of prescribing drugs for older adults while providing state-of-the-art guidelines for safe patient care. An evidence-based, quick-access reference for adult gerontology nurse practitioners and related providers, this text describes a holistic, patient-centered approach to prescribing drugs to older adults.
Автор: Charles R. Schuster; Michael J. Kuhar Название: Pharmacological Aspects of Drug Dependence ISBN: 364264631X ISBN-13(EAN): 9783642646317 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Pablo Avanzas; Juan Carlos Kaski Название: Pharmacological Treatment of Chronic Stable Angina Pectoris ISBN: 3319173316 ISBN-13(EAN): 9783319173313 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is intended for general cardiologists and other physicians involved in the care of patients with chronic stable angina (CSA). The management of these patients encompasses lifestyle modification, control of coronary artery disease risk factors, evidence-based pharmacological therapy and patient education.
Автор: SA,ren C. Dam Название: The Pharmacological Guide to Montelukast ISBN: 1536163945 ISBN-13(EAN): 9781536163940 Издательство: Nova Science Рейтинг: Цена: 11562.00 р. Наличие на складе: Невозможна поставка.
Описание: The Pharmacological Guide to Montelukast opens by presenting the most recent updates on the improvement of montelukast stability and bioavailability, along with some innovative formulations produced by this research. Montelukast is a leukotriene modifier with bronchoprotective and anti-inflammatory actions frequently used in asthma management. As such, the authors go on to assess the impact of the addition of montelukast to ongoing asthma treatment in terms of improvement in clinical parameters, symptom control and quality of life. The closing chapter focuses on leukotrienes, formed by leukocytes, which are inflammatory mediators that play an active role in early and late-phase immune response. This group includes montelukast, zafirlukast and prankulast.
Автор: N. Allon; S. Shapira; B.A. Weissman Название: Biochemical, Pharmacological, and Clinical Aspects of Nitric Oxide ISBN: 1461357772 ISBN-13(EAN): 9781461357773 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A decade ago, for most scientists investigating various issues in life sciences the word "NO" was used in a negative context. NO is implicated in long-term potentiation (LPT), a principal process involved in memory consolidation and it is considered as the main biochemical substance responsible for penile erection.
Автор: Jay Roberts Название: Pharmacological Intervention in the Aging Process ISBN: 1468477951 ISBN-13(EAN): 9781468477955 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the nearly three years that have elapsed since our first Philadelphia Symposium on Aging, our activities and interactions have expanded. For the first symposium, a variety of topics relating to the study of aging, ranging from phenomena at the cellular level to phenomena in disease states, were selected for consideration.
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