This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Patil Popat M Название: Discoveries In Pharmacological Sciences ISBN: 9814355070 ISBN-13(EAN): 9789814355070 Издательство: World Scientific Publishing Рейтинг: Цена: 27720.00 р. 39600.00-30% Наличие на складе: Есть (1 шт.) Описание: Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This title contains the history of herbal medicine as it emerged about 5,000 years ago.
Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.
Автор: Shabir H. Lone; Khursheed Ahmad Bhat; Mohammad Akb Название: Chemical and Pharmacological Perspective of Artemisia amygdalina ISBN: 3319252151 ISBN-13(EAN): 9783319252155 Издательство: Springer Рейтинг: Цена: 9141.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the chemical and biological properties of Artemisia amygdalina Decne, a critically endangered and endemic plant species in the the high-altitude Kashmir Himalayas, which has a high pharmacological potential.
Автор: Wantanabe Название: Pharmacological Research on Traditional Herbal Medicines ISBN: 9057020548 ISBN-13(EAN): 9789057020544 Издательство: Taylor&Francis Рейтинг: Цена: 24499.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book introduces some of the most pharmacological research on traditional herbal medicines and examines potential and functional applications of these agents in modern healthcare systems. It describes state-of-the-art pharmacological methods of traditional herbal medicines.
Название: Pharmacological aspects of molecular recognition ISBN: 1594546762 ISBN-13(EAN): 9781594546761 Издательство: Nova Science Рейтинг: Цена: 9186.00 р. Наличие на складе: Невозможна поставка.
Описание: Describes recognition of the receptors by drugs as a complex phenomenon. This monograph also presents the description of molecular structure information necessary to achieve specific receptors without getting lost among huge amounts of non-specific acceptors.
Автор: Avanzas, Pablo, Clemmensen, Peter Название: Pharmacological Treatment of Acute Coronary Syndromes ISBN: 1447154231 ISBN-13(EAN): 9781447154235 Издательство: Springer Рейтинг: Цена: 6288.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents key knowledge that a cardiovascular professional needs to know on a day-to-day basis, written in a quick-access, no-nonsense format.
Описание: This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters, written by the world's leading scientists, provides an understanding of anatomy, neurochemistry, and cellular and molecular effects. Such an understanding sheds light on the pathophysiology of central disorders involving the basal ganglia and leads to new approaches for the treatment of diseases such as Parkinson's disease and schizophrenia, and also addictions to psychostimulants such as cocaine and amphetamines.
Описание: Jacket Description/Back:
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes features important insights into the applications of fullerenes and carbon nanotubes. It discusses the fullerene and nanotubes derivatives which are effective against viruses, cells, and bacteria and those which are able to interact and inhibit certain enzymes. Also covered in this book are the formation of complex structures between biologically active molecules and carbon materials. Furthermore, the application of fullerenes in certain medical therapies is explored, including the very recent discovery of new bio-compatible media which could be used as carriers in the delivery of fullerenes in vivo. An additional topic of this text is the formation of hybrids between nanotubes and biological molecules and their use as chemical sensors.
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes will be a useful tool of reference for researchers, postgraduates and advanced undergraduates in the Chemical, Biomedical, and Materials sciences.
Publisher Marketing:
Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks.
Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.
In addition, the funtionalization of nanotubes has not only produced relatively simple derivatives, but also complex hybrids with biological macromolecules, which show unique supramolecular architecture and which are promising in many medical applications.
The application of fullerenes and nanotubes in medicine is at the frontier of our knowledge, thus the work in this field represents the basis for future novel developments.
Описание: Integrating Psychological and Pharmacological Treatments for Addictive Disorders distills the complex literature on addiction, offering a curated toolbox of integrated pharmacological and psychotherapeutic treatments in chapters authored by leading experts.
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