Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.
Автор: Blossey, Ralf (Interdisciplinary Research Institute, University of Lille, Villeneuve d`Ascq, France) Название: Handbook of Drug Metabolism, Third Edition ISBN: 0367779765 ISBN-13(EAN): 9780367779764 Издательство: Taylor&Francis Рейтинг: Цена: 7348.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug transporters and metabolic activation
Название: A Handbook of Bioanalysis and Drug Metabolism ISBN: 0367394421 ISBN-13(EAN): 9780367394424 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting - until now.
A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug-drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills.
This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.
Автор: Woolf, Thomas Название: Handbook of Drug Metabolism ISBN: 0824702298 ISBN-13(EAN): 9780824702298 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: K.W. Bock; Frederick C. Kauffman; B. Burchell; M. Название: Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity ISBN: 3642784313 ISBN-13(EAN): 9783642784316 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In-depth coverage of advances in molecular biology, indicating the importance of drug and xenobiotic conjugates as transport forms of biologically active compounds. Part Two deals with the regulation of Phase II conjugation, while Part Three critically reviews the importance of drug conjugates in pharmacology and toxicology.
Автор: Jordan Lisa Название: Handbook of Iron Metabolism ISBN: 1632412381 ISBN-13(EAN): 9781632412386 Издательство: Неизвестно Цена: 16553.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Iron is an essential of human life. This book deals with various aspects related to iron metabolism. Iron has a variety of functions in the body, inclusive of the metabolism of oxygen in a range of biochemical activities. Iron, as heme or in its nonheme f
Автор: J.F. Acar; G.H. Hitchings Название: Inhibition of Folate Metabolism in Chemotherapy ISBN: 3642818927 ISBN-13(EAN): 9783642818929 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: E. Eichenberger; P.P. Foa; T.A.I. Grillo Название: Erzeugung von Krankheitszust?nden durch das Experiment ISBN: 3642998984 ISBN-13(EAN): 9783642998980 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: D.J. Atherton Название: Pharmacology of the Skin II ISBN: 3642740561 ISBN-13(EAN): 9783642740565 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Evans Название: Guide to Bioanalysis and Drug Metabolism.2003 ISBN: 0415275202 ISBN-13(EAN): 9780415275200 Издательство: Taylor&Francis Цена: 4592.00 р. Наличие на складе: Нет в наличии.
Описание: Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. This textbook provides a guide for students of this field.
Автор: Dey Aparajita Название: Cytochrome P450 2e1: Its Role in Disease and Drug Metabolism ISBN: 9401782024 ISBN-13(EAN): 9789401782029 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.
Автор: Gibson, G. Gordon Skett, Paul Название: Introduction to drug metabolism ISBN: 0748760113 ISBN-13(EAN): 9780748760114 Издательство: Cengage Learning Рейтинг: Цена: 11403.00 р. Наличие на складе: Нет в наличии.
Описание: A well organised, clearly written introduction to the mechanisims by which the body metabolises and excretes administered drugs.
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