Описание: Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.
Автор: Xin-Long Ni; Xin Xiao; Hang Cong; Zhu Tao Название: Supramolecular Assemblies of Cucurbit[n]urils with Metal Ions ISBN: 3662466287 ISBN-13(EAN): 9783662466285 Издательство: Springer Рейтинг: Цена: 7182.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book shows the various porous structures and supramolecular architectures that result from the cucurbituril-based coordination, hydrogen bonding, ion-dipole interactions, ГЇВїВЅ ГЇВїВЅ ГЇВїВЅ ГЇВїВЅ ГЇВїВЅ stacking and C-HГЇВїВЅ ГЇВїВЅ ГЇВїВЅ ГЇВїВЅ processes.
Описание: In 10 inspiring chapters, Volume 43 of Metal Ions in Biological Systems focuses on the vibrant research area related to the cycling of elements, metals, and nonmetals in biology and geology. It critically highlights the biogeochemistry of hydrogen, oxygen, nitrogen, sulfur, and phosphorus, examines the interrelations between the availability of iron, phytoplankton growth, and the carbon cycle, considers the biogeochemical cycling of mercury and lead, and includes a chapter devoted to cadmium, a highly toxic element that is also a micronutrient for phytoplankton. This volume contains more than 50 illustrations along with more than 1300 references for further research on the subject.
Advances in Microbial Physiology, Volume 70 continues the long tradition of topical, important, cutting-edge reviews in microbiology with this new volume covering a variety of topics, including Bacterial Hemoprotein Sensors of NO: H-NOX and NosP, Manganese in Marine Microbiology, Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface, Metal-Based Combinations that Target Protein Synthesis by Fungi, Transition Metal Homeostasis in Streptococcus Pyogenes and Streptococcus Pneumoniae, Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal Applications, Metal Resistance and Its Association with Antibiotic Resistance, and The Role of Intermetal Competition and Mis-Metalation in Metal Toxicity.
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Structural and Catalytic Roles of Metal Ions in RNA ISBN: 3110442825 ISBN-13(EAN): 9783110442823 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes structural and catalytic roles of metal ions in RNA in an authoritative and timely manner. It deals with diffuse metal ion binding, RNA quadruplexes, the regulation of riboswitches, metal ions and ribozymes, including artificial
Автор: Simon Silver; William Walden Название: Metal Ions in Gene Regulation ISBN: 1461377455 ISBN-13(EAN): 9781461377450 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is the first volume on the role of metal ions in regulating genes to focus not only on toxicity effects of metals but also on the role of metal ions in normal metabolisms, in both prokaryotes and in eukaryotes.
Название: Metal Ions In Biological Systems, Volume 44 ISBN: 0367454211 ISBN-13(EAN): 9780367454210 Издательство: Taylor&Francis Рейтинг: Цена: 9492.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, en
Автор: Astrid Sigel, Helmut Sigel, Roland K.O. Sigel Название: Metal Ions in Toxicology: Effects, Interactions, Interdependencies ISBN: 3110442817 ISBN-13(EAN): 9783110442816 Издательство: Walter de Gruyter Рейтинг: Цена: 16727.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: MILS-8 deals with the risk assessment of toxic metal ions and their interdependencies focusing on humans and their organs; thus it carries on the topic of MILS-7 that centered on the environment. This book is of special relevance for researchers in
Описание: A comprehensive overview of the molecular nature of metal ions in nutrition, toxicology and pharmacology.
Автор: Wolfgang Linert; Henryk Kozlowski Название: Metal Ions in Neurological Systems ISBN: 3709116783 ISBN-13(EAN): 9783709116784 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores key topics in the area of metal ions in the brain, focusing on the role of metal ions in neurological systems by describing their advantageous functions in brain activity as well as their poisonous features, in neurodegenerative disorders.
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