Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment, Eckerman, David A.
Автор: Nordberg, Gunnar Название: Risk Assessment for Human Metal Exposures ISBN: 0128042273 ISBN-13(EAN): 9780128042274 Издательство: Elsevier Science Рейтинг: Цена: 17180.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA -TKTD can be used. In addition, it presents tactics on how information generated by such methods can be confirmed by epidemiological data. Furthermore, it demonstrates how epidemiological data can be confirmed and evaluated by the examined models and considerations.
This resource uniquely integrates several important topics, such as risk assessment, characterization, management and communication--the classic risk assessment paradigm--with mode of action, TKTD, and epidemiology, all topics related to human exposure. Written by pioneers in the field, this book is an essential reference for researchers, students and technicians in toxicology and risk assessment.
Covers fundamental risk assessment concerns for the effects of metals on human health
Provides an easy-to-use structure to quickly locate specific methods
Uses case studies to illustrate the methods and theories described
Written to be understood by students, researchers and industry workers who need to conduct risk assessment in metals and human health
Описание: This book provides an overview of current available biomarkers and human biomonitoring programs in environmental health, addressing current concerns regarding adverse health effects from environmental exposures.
Описание: This book features papers presented at a workshop discussing current knowledge about the biological effects of low level exposures (BELLE). The book is designed to help establish a scientific base for future BELLE initiatives and is focused on the issue of the toxicological implications of biological adaptations.
Treating nuclear, biological, and chemical agent exposures presents a unique set of challenges. These scenarios usually involve multiple exposures, sometimes even mass exposures, from a single, often poorly-defined, event. Early symptoms are not distinct and can often be variable. Laboratory analyses may be required from environmental, often nonbiological, specimens. Scene evaluation and pre-hospital decontamination may turn out to be the most important intervention. Hospital resource utilization must be a consideration. Even the pathologist performing autopsies needs adequate preparation.
It is with these considerations in mind that the Handbook of Nuclear, Biological, and Chemical Agent Exposures was created. Taking a concise yet comprehensive, clinical approach to the treatment of these exposures, the authors provide concise information on radiation substances, biological agents, chemical toxins, laboratory tests, and antidotes. The book includes essays on topics such as Field Identification and Decontamination of Toxins, Bioterrorism and the Skin, and Mass Exposures Involving the Pediatric Population. A quick review of the contents will tell you that this book contains the tools you need when facing the formidable tasks of diagnosing and treating nuclear, biological, and chemical agent exposures.
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