Автор: Randall J. Mrsny, Ann Daugherty Название: Proteins and Peptides: Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes ISBN: 1420078062 ISBN-13(EAN): 9781420078060 Издательство: Taylor&Francis Рейтинг: Цена: 19293.00 р. 27562.00-30% Наличие на складе: Есть (1 шт.) Описание: Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is an invaluable source for drug discovery and development scientists in the biopharmaceutical industry who frequently navigate the maze of protein and peptide pharmacokinetics, pharmacodynamics, and metabolism.
Key features include:
issues related to delivery of protein and peptide therapeutics in elderly populations and pharmacogenomics
lessons learned on the major marketed areas of proteins and peptides, including interleukins, interferons, growth factors, and peptide hormones
innovations for protein and peptide delivery such as needle-less delivery
strategies for delivery of these molecules to locations such as the eye and brain
generic issues of proteins and peptides
Автор: Ryadnov Maxim Название: Amino Acids, Peptides and Proteins ISBN: 1782620591 ISBN-13(EAN): 9781782620594 Издательство: Royal Society of Chemistry Рейтинг: Цена: 66517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology/chemistry interface.
Описание: Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions.
Название: Cyclic Peptides: From Bioorganic Synthesis to Applications ISBN: 1782625283 ISBN-13(EAN): 9781782625285 Издательство: Royal Society of Chemistry Рейтинг: Цена: 35693.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Автор: Tran Название: Capillary Electrophoresis of Proteins and Peptides ISBN: 1493940120 ISBN-13(EAN): 9781493940127 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive survey of recent developments and applications of high performance capillary electrophoresis in the field of protein and peptide analysis with a distinct focus on the analysis of intact proteins. With practical detail, the contents cover different modes of capillary electrophoresis (CE) useful for protein and peptide analysis, CZE, CIEF, ACE, CGE, and different types of application such as the quality control of therapeutic proteins and monoclonal antibodies, clinical analyses of chemokines in tissues, qualitative and quantitative analysis of vaccine proteins, and determination of binding constants in complexes involving peptides or proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and exhaustive, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols serves both beginners and experts with a collection of the current and most active topics in this vital field of study.
Автор: Nguyet Thuy Tran; Myriam Taverna Название: Capillary Electrophoresis of Proteins and Peptides ISBN: 1493981536 ISBN-13(EAN): 9781493981533 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive survey of recent developments and applications of high performance capillary electrophoresis in the field of protein and peptide analysis with a distinct focus on the analysis of intact proteins. With practical detail, the contents cover different modes of capillary electrophoresis (CE) useful for protein and peptide analysis, CZE, CIEF, ACE, CGE, and different types of application such as the quality control of therapeutic proteins and monoclonal antibodies, clinical analyses of chemokines in tissues, qualitative and quantitative analysis of vaccine proteins, and determination of binding constants in complexes involving peptides or proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and exhaustive, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols serves both beginners and experts with a collection of the current and most active topics in this vital field of study.
Автор: Langel, Ulo , Cravatt, Benjamin F. , Graslund, A Название: Introduction to Peptides and Proteins ISBN: 0367384876 ISBN-13(EAN): 9780367384876 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human cells produce at least 30,000 different proteins. Each has a specific function characterized by a unique sequence and native conformation that allows it to perform that function. While research in this post-genomic era has created a deluge of invaluable information, the field has lacked for an authoritative introductory text needed to inform researchers and students in all of those fields now concerned with protein research.
Introduction to Peptides and Proteins brings together some of the most respected researchers in protein science to present a remarkably coherent introduction to modern peptide and protein chemistry. The first sections of the book delve into -
Basic peptide and protein science from assembly through degradation
Traditional and emerging research methods including those used in bioinformatics and proteomics
New computational approaches and algorithms used to find patterns in the vast data collected by sequencing projects
After providing a foundation in tools and methods, the authors closely examine six protein families, including representative classes such as enzymes, cell-surface receptors, antibodies, fibrous proteins, and bioactive peptide classes. They concentrate on biochemical mechanisms and where possible indicate therapeutic or biotechnical possibilities.
Then focusing on clinical aspects, the authors investigate misfolding as found in prion diseases, miscleavage as found in Alzheimer's, and mis-sequencing as found with some cancers. Drawing from some of their own research, the authors summarize recent achievements and emerging applications. They discuss the use of proteins and peptides as drugs and the solid-phase synthesis required for drug production. They also look at the use of peptides as functional biomolecules and research tools.
Описание: This volume provides computational methods and reviews various aspects of computational studies of protein aggregation. Chapters discuss the relationship between protein misfolding and protein aggregation, methods of prediction of aggregation propensities of protein, peptides, protein structure, results of computer simulations of aggregation, and computational simulations focused on specific diseases such as Alzheimer’s, Parkinson’s, and preeclampsia. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computer Simulations of Aggregation of Proteins and Peptides aims to ensure successful results in the further study of this vital field.
Название: Amino Acids, Peptides and Proteins: Volume 42 ISBN: 1788010027 ISBN-13(EAN): 9781788010023 Издательство: Royal Society of Chemistry Рейтинг: Цена: 66517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas in topics such as magnetic resonance studies of membrane active peptides, proteins and peptides for the diagnosis and therapy of Leishmania donovani parasite infections and advances in the design of ligands interacting with proteases causing infectious respiratory syndrome. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference on developments in this area now and looking to the future.
Автор: Ryadnov Maxim, Hudecz Ferenc Название: Amino Acids, Peptides and Proteins: Volume 43 ISBN: 1788013670 ISBN-13(EAN): 9781788013673 Издательство: Royal Society of Chemistry Рейтинг: Цена: 66517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Compiled by leading researchers in their subject, Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology and chemistry interface.
Описание: Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
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