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Antiangiogenic Cancer Therapy, 


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Цена: 9798.00р.
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Название:  Antiangiogenic Cancer Therapy
ISBN: 9780367388812
Издательство: Taylor&Francis
Классификация:


ISBN-10: 0367388812
Обложка/Формат: Paperback
Страницы: 876
Вес: 1.62 кг.
Дата издания: 20.12.2019
Язык: English
Размер: 252 x 178 x 43
Читательская аудитория: Tertiary education (us: college)
Основная тема: Oncology
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание: Top Investigators Explore the Complexities of Angiogenesis Cancer Research

The targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies. However, as of yet, no antiangiogenic agent used as a monotherapy has demonstrated a survival benefit in a randomized Phase III trial. The combination of bevacizumab, the first FDA approved angiogenesis inhibitor, with cytotoxic regimens has led to survival benefits in cancer patients. This has raised important questions about the complexities inherent in the clinical application of angiogenesis inhibitors.

Compiles the results of four decades of progress

Integrating fundamental concepts with therapeutic strategies, Anti-Angiogenic Cancer Therapy promotes the idea that an understanding of the molecular and cellular regulation of angiogenesis leads to optimal therapeutic strategies and positive clinical results. It brings together contributions from leading researchers to provide the most authoritative and encyclopedic volume available on this subject.

  • Examines the role of angiogenesis in cancer, including strategies to prolong the nonangiogenic dormant state of human tumors, molecular mechanisms and cellular regulation of angiogenesis in solid tumors and hematologic malignancies, and the regulation of angiogenesis by the tumor microenvironment.
  • Covers specific molecular targets for inhibiting angiogenesis in cancer therapy.
  • Discusses clinical trial design and translational research approaches essential for identifying and developing effective angiogenesis inhibitors.
  • Outlines current understanding of the molecular biology of each cancer type followed by discussions that examine strategies for targeting angiogenesis in specific cancers.
  • This volume celebrates progress made in four decades, and more importantly, it provi



    Antiangiogenic Agents in Cancer Therapy

    Автор: Teicher Beverly A., Ellis Lee M.
    Название: Antiangiogenic Agents in Cancer Therapy
    ISBN: 1493956280 ISBN-13(EAN): 9781493956289
    Издательство: Springer
    Рейтинг:
    Цена: 27950.00 р.
    Наличие на складе: Есть у поставщика Поставка под заказ.

    Описание: Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.


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