Описание: Abstract: Design, development, and coupling of an electrospray ionization (ESI) source with a Fourier Transform Ion Cyclotron (FTICR) Mass Spectrometer (MS). Developed ESI source was used for detection and characterization of small and large molecules. Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Internal and External Source Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry" by Ragulan Ramanathan, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Описание: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Описание: Employing 'second generation' matrices.- (MA)LDI MS mass spectrometry imaging at high specificity and sensitivity.- Techniques for fingermark analysis using MALDI MS - a practical overview.- Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analyis.- MALDI biotyping for microorganism identification in clinical microbiology.- Future applications of MALDI-TOF MS in microbiology.- MALDESI: Fundamentals, direct analysis, and MS imaging.- Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI.- Efficient production of multiply charged MALDI ions.- Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species.- Quantitative MALDI MS using Ionic Liquid Matrices.- Disease profiling by MALDI MS analysis of biofluids.- Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis.- Coupling liquid MALDI MS to liquid chromatography.
Автор: Zaitsu, Kei Название: Ambient Ionization Mass Spectrometry In Life Sciences ISBN: 0128172207 ISBN-13(EAN): 9780128172209 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Ambient Ionization Mass Spectrometry in Life Sciences: Principles and Applications is a systematic introduction to this rapidly expanding area of study. Underlying principles of each technique are explained in detail, along with discussions on their applications across life science disciplines. Ambient ionization has recently emerged as one of the hottest and fastest growing topics in mass spectrometry, hence this book is not just for analysts and researchers who use and study mass spectrometry. This volume would be of interest to anyone who works in or studies analytical chemistry, omics sciences (including metabolomics), pharmacokinetics, forensic science or drug analysis.
Описание: Tian Lu`s dissertation describes major advances in ultrathin-layer chromatography (UTLC), liquid chromatography and surface-assisted laser desorption ionization (SALDI), and matrix-enhanced SALDI (ME-SALDI) mass spectrometry.
Описание: Tian Lu`s dissertation describes major advances in ultrathin-layer chromatography (UTLC), liquid chromatography and surface-assisted laser desorption ionization (SALDI), and matrix-enhanced SALDI (ME-SALDI) mass spectrometry.
Описание: The purpose of this text is to introduce engineering and science students to the basic underlying physics and chemistry concepts that form the foundation of plasma science and engineering. It is an accessible primer directed primarily at those students who, like the general public, simply do not understand exactly what a plasma or gas discharge is nor do they even necessarily have the fundamental background in statistical thermodynamics, gas dynamics, fluid dynamics, or solid state physics to effectively understand many plasma and gas discharge principles.At the conclusion of this text, the reader should understand what an ion is, how they move, the equations we use to describe these basic concepts, and how they link to the aforementioned topics of plasmas and gas discharges. This book is focused on specific concepts that are important to non-equilibrium, low temperature gas discharges. These discharges find wide applicability today and are of significant interest to the scientific and engineering communities.
Описание: Abstract: Measurements of the velocity dependence of the absolute total ionization cross section of argon atoms upon impact with selected metastable states of helium atoms are reported. A low voltage D. C. discharge was used as the source of the excited atoms, and a rotating slotted disk selector was used for velocity selection of the excited atoms. Selection of th electronic spin state of the excited atoms was accomplishe by irradiation of the excited atoms with radiation from a helium d i s cha r g e 1 amp . Ionization of the argon target atoms by metastable. heliui atoms was studied by the gas cell technique in which all ionization products were collected. The ionization measurements were of sufficient precision to allow simultaneous determination of the cross section and the secondary electron ejection efficiency for each metastable state of helium. The secondary electron ejection efficiency of triplet me tas table helium atoms on an electroplated gold surface was determined to be 0.440 + 0.018 in the presence of argon gas. The secondary electron ejection efficiency of singlet: metastable atoms was determined to be 0.582 + 0.024 under similar conditions. The local ionization cross section for the He(2 S)-Ar system was found to increase almost linearly from S.8 A to 2.1.95 with an increase of relative velocity from 1162 from 9.8 to 26.2 K 2 with an increase in relative m/sec to 2787 in/ sec. After an initial increase, of the cross section velocity from 989 m/sec to 2058 m/sec, the velocity dependence of the cross: section of the He (2 S)-Ar system entered a saturation region in which the cress section changed very little with relative velocity. The collision energy dependence of the He(2"S)-Ar system was also used to determine the values of adjustable parameters present in a current theory based on the potential curve model for Penning and associative Pennine ionization. Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "The Velocity Dependence of the Absolute Total Ionization Cross Section for Collisions of Argon Atoms With Singlet and Triplet Metastable Helium Atoms" by Michael Read Woodard, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Автор: M. Ranny Название: Thin-Layer Chromatography with Flame Ionization Detection ISBN: 940108159X ISBN-13(EAN): 9789401081597 Издательство: Springer Рейтинг: Цена: 13060.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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