Автор: Marco Gattorno Название: Familial Mediterranean Fever ISBN: 3319146149 ISBN-13(EAN): 9783319146140 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic autoinflammatory disease. The opening chapters explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies. A large part of the book is then devoted to a detailed description of the typical and atypical clinical presentations, the disease course, and potential complications in both pediatric and adult patients. Guidance is provided on the measurement of disease severity and the management of patients in daily practice. The advice regarding treatment is based on the best currently available evidence and attention is also paid to important emerging treatments.The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Monogenic autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Familial Mediterranean fever itself is due to a mutation in the MEFV gene, which codes for the protein pyrin; it is characterized by periodic fever and episodes of painful inflammation in the abdomen, chest, and joints. Familial Mediterranean Fever will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with the disease.
Описание: This book explores the development of familial discourse within a chronological frame, commencing with the More family and concluding with the Cavendish group. It explores the way in which the support of family groups enabled women to participate in literary production, whilst closeting them within a form of writing that encompassed style or theme.
Over the centuries, drama has been an influential and imaginative medium for presenting, analysing and offering ways of resolving real or fictional battles. This volume provides readers with a timely study of inter-generational conflicts and crises as seen through the eyes of male and female British and Irish playwrights from the medieval period to the twenty-first century. The contributions suggest that at the heart of inter-generational discord lies various crises between (the) age(d) and youth or, more generally, the idea of what is «old» and «new». The interaction and co-existence of age and youth in their embodied, symbolic or conceptual forms is the topic of this volume. The collection is built around the words «age(d)»/«young», which denote both the biological age of the characters and the more conceptual potential of these terms. Ultimately, the contributors to this collection of essays analyse not only the idea of inter-generationality within selected dramatic works but also inter-generational conflicts seen in clashes of cultures, artistic visions, concepts and aesthetic idea(l)s.
Описание: Abstract: The purpose of this study was to assess the family's influence on the moral reasoning of adolescent first-time offenders. Specifically, this study explored the relationship between the adolescent's level of moral reasoning and the parent's level of moral reasoning; the parent's style of parenting; the level of family functioning; the adolescent's age; the adolescent's gender; and the family's socio-economic status. It was hoped that the research findings might be used in the development of adolescent crime prevention programs. Although this sample of adolescents demonstrated a significantly lower level of moral reasoning as compared with adolescents of the same age in the general population, there were no significant relationships found between the adolescents' moral reasoning level and the six variables. There were, however, statistically significant relationships between particular parenting styles and the level of family health. Discussion on these results, the study's limitations, and suggestions for future research were then presented. Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Familial Influences on the Moral Reasoning of Adolescent First-time Offenders" by Stephen Alphonse Giunta, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Organ transplant in Mexico is overwhelmingly a family matter, utterly dependent on kidneys from living relatives—not from stranger donors typical elsewhere. Yet Mexican transplant is also a public affair that is proudly performed primarily in state-run hospitals. In Domesticating Organ Transplant, Megan Crowley-Matoka examines the intimate dynamics and complex politics of kidney transplant, drawing on extensive fieldwork with patients, families, medical professionals, and government and religious leaders in Guadalajara. Weaving together haunting stories and sometimes surprising statistics culled from hundreds of transplant cases, she offers nuanced insight into the way iconic notions about mothers, miracles, and mestizos shape how some lives are saved and others are risked through transplantation. Crowley-Matoka argues that as familial donors render transplant culturally familiar, this fraught form of medicine is deeply enabled in Mexico by its domestication as both private matter of home and proud product of the nation. Analyzing the everyday effects of transplant’s own iconic power as an intervention that exemplifies medicine’s death-defying promise and commodifying perils, Crowley-Matoka illuminates how embodied experience, clinical practice, and national identity produce one another.
Автор: Brajendra C. Sutradhar Название: Dynamic Mixed Models for Familial Longitudinal Data ISBN: 1461428017 ISBN-13(EAN): 9781461428015 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a theoretical foundation for analysis of discrete data such as count and binary data in the longitudinal setup. It presents differences between the familial and longitudinal correlation models, and illustrations of real life data analysis.
Автор: Giovanni Corso; Franco Roviello Название: Spotlight on Familial and Hereditary Gastric Cancer ISBN: 940079715X ISBN-13(EAN): 9789400797154 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers management of hereditary diffuse gastric cancer patients, focusing on E-cadherin germline mutations, clinical criteria definition, genetic screening and molecular mechanisms, pathology and microscopic features, surgical treatment and more.
Автор: Nose, Vania Название: Diagnostic Pathology: Familial Cancer Syndromes ISBN: 0323712045 ISBN-13(EAN): 9780323712040 Издательство: Elsevier Science Рейтинг: Цена: 39748.00 р. Наличие на складе: Поставка под заказ.
Описание: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome- and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors.
Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout. Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other alterations; and details on personalized medicine targeted to specific genes Features more than 2,200 images throughout, including clinical and radiological images, algorithms, graphics, gross pathology, histology, and a wide range of special and immunohistochemical stains-all carefully annotated to highlight the most diagnostically significant factors Features time-saving bulleted text, key facts in each chapter, an extensive index, and numerous tables for quick reference and thorough understanding Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Описание: Based on long-term ethnographic fieldwork among Tongan migrant mothers and adult daughters in Australia, anthropologist Makiko Nishitani provides a unique account of how gifts, money, and information flow along the connections of kin and kin-like relationships. Desire, Obligation, and Familial Love challenges the conventional discourse on migration, which typically characterizes intergenerational changes from tradition to modernity, from relational to individual, and from obligation to autonomy and freedom. Rather, through an intimate examination of Tongan women's everyday engagement with kinship relationships, Nishitani highlights how migrant women and their daughters born outside Tonga together create a field of relationships with kin and kin-like people, and navigate between individualistic, personal desires and familial duties and obligations. Their negotiations are not limited to a local frame of reference, but encompass vast distances, including relationships with relatives in places like Australia, New Zealand, the United States, and the "home" island nation. Tongan women manage these relationships across diverse modes of communication: face-to-face interactions in homes and at church, lengthy telephone conversations on fixed phone lines in kitchens, and interactions on social media accessed on living room computers shared between neighboring households. Relationships between migrant mothers and second-generation daughters are suffused with warmth and empathy, as well as tensions and misunderstandings. Nishitani's work demonstrates the critical contemporary relevance of classical anthropological kinship studies and gift theories as tools that can help us to understand transnationalism in the "digital" age. Through reflections on feminist geography, social theory of technology, Bourdieu's field theory, and media studies, Nishitani makes a convincing call for anthropologists to use relationships rather than geographical places as a site of anthropological fieldwork in order to understand the sociality of diasporic people. Filled with rich, intimate portrayals of diasporic women's everyday lives and the everyday politics of familial relationships, Desire, Obligation, and Familial Love will appeal to students and scholars of the anthropology of migration, of communication technologies and social media, and of gender and familial relationships, as well as to those interested in fieldwork methodology, transnational and migration studies, and Pacific Studies.
Автор: Call Andrew Taylor Название: Chicago: A Civic, Industrial, and Familial History ISBN: 1541115740 ISBN-13(EAN): 9781541115743 Издательство: Неизвестно Цена: 6035.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Maurizio Ponz de Leon Название: Familial and Hereditary Tumors ISBN: 3642850782 ISBN-13(EAN): 9783642850783 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From the 1960s onward, the pioneer work of a few investigators clearly showed that hereditary factors were not only related to rare neoplasms, but could also be respon- sible for the occurrence of a sizeable fraction of tumors that do not usually show features of inheritance (as in the case of breast or colorectal cancer).
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