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Neuronal Chloride Transporters In Health And Disease, Tang, Xin


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Автор: Tang, Xin
Название:  Neuronal Chloride Transporters In Health And Disease
ISBN: 9780128153185
Издательство: Elsevier Science
Классификация:
ISBN-10: 0128153180
Обложка/Формат: Paperback
Страницы: 650
Вес: 1.83 кг.
Дата издания: 01.07.2020
Язык: English
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field.




Neurotransmitter Transporters

Автор: B?nisch
Название: Neurotransmitter Transporters
ISBN: 1493937634 ISBN-13(EAN): 9781493937639
Издательство: Springer
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Цена: 18167.00 р.
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Описание: The volume aims at providing an overview of cutting-edge methods and protocols used in neuroscience and neurological research. Neurotransmitter Transporters: Investigative Methods will be of interest to scientists, graduate students, and advanced undergraduates who seek an overview of methods and protocols in this field of neuroscience. It will also be of interest to physicians who are carrying out imaging and postmortem studies of neurotransmitter transporters in the human brain. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Neurotransmitter Transporters: Investigative Methods aims to ensure successful results in thefurther study of this vital field.

Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease

Автор: Francisco Gonzalez-Lima
Название: Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease
ISBN: 0306460246 ISBN-13(EAN): 9780306460241
Издательство: Springer
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Цена: 34799.00 р.
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Описание: Proceedings of an International Symposium held in New Orleans, Louisiana, October 28, 1997

ABC Transporters and Human Genetic Disease

Автор: Karobi Moitra
Название: ABC Transporters and Human Genetic Disease
ISBN: 1615043780 ISBN-13(EAN): 9781615043781
Издательство: Mare Nostrum (Eurospan)
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Цена: 6237.00 р.
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Описание: The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates so far studied. The human ABC transporter superfamily contains 48 genes, subdivided into 7 subfamilies ranging from A to G (based on sequence homology of their nucleotide binding domains). The ABC proteins encoded by these genes are ATP-driven transmembrane pumps, some of which possess the capacity to efflux harmful toxic substances and therefore play a key role in xenobiotic defense. ABC proteins have been evolutionarily conserved from bacteria to humans and multiple gene duplication and deletion events in the ABC genes indicate that the process of gene evolution is still ongoing. Polymorphisms and variations in these genes are linked to variations in expression, function, drug disposition, and drug response. Single nucleotide polymorphisms (SNPs) in these genes could be markers of individual risk for adverse drug reactions or susceptibility to complex diseases. The pharmacogenetics of this unique family of transporters is still under study; however, in the context of human health, it is a well-known fact that variations in these transporters are the underlying cause for several human diseases including cystic fibrosis, Pseudoxanthoma elasticum (PXE), and X-linked adenoleukodystrophy (X-ALD).

Neurotransmitter Transporters

Автор: Heinz B?nisch; Harald H. Sitte
Название: Neurotransmitter Transporters
ISBN: 1493981323 ISBN-13(EAN): 9781493981328
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Neurotransmitter Transporters: Investigative Methods aims to ensure successful results in thefurther study of this vital field.

Neurotransmitter Transporters

Автор: Maarten E. A. Reith
Название: Neurotransmitter Transporters
ISBN: 1617372676 ISBN-13(EAN): 9781617372674
Издательство: Springer
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Цена: 28732.00 р.
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Facilitative Glucose Transporters

Автор: Gwyn W. Gould
Название: Facilitative Glucose Transporters
ISBN: 0412132915 ISBN-13(EAN): 9780412132919
Издательство: Springer
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Цена: 21661.00 р.
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Glial Amino Acid Transporters

Автор: Arturo Ortega; Arne Schousboe
Название: Glial Amino Acid Transporters
ISBN: 331955767X ISBN-13(EAN): 9783319557670
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This ambitious compendium provides an extensive overview on the "supporting cells" of the vertebrate central nervous system, these being glial cells which far outnumber neurons but are much less understood.

GABA: Receptors, Transporters and Metabolism

Автор: Chikako Tanaka; Norman G. Bowery
Название: GABA: Receptors, Transporters and Metabolism
ISBN: 3034898584 ISBN-13(EAN): 9783034898584
Издательство: Springer
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Цена: 14673.00 р.
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In vitro neuronal networks :

Автор: Michela Chiappalone, Valentina Pasquale
Название: In vitro neuronal networks :
ISBN: 3030111342 ISBN-13(EAN): 9783030111342
Издательство: Springer
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Цена: 22359.00 р.
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Описание: This book provides a comprehensive overview of the incredible advances achieved in the study of in vitro neuronal networks for use in basic and applied research. These cultures of dissociated neurons offer a perfect trade-off between complex experimental models and theoretical modeling approaches giving new opportunities for experimental design but also providing new challenges in data management and interpretation. Topics include culturing methodologies, neuroengineering techniques, stem cell derived neuronal networks, techniques for measuring network activity, and recent improvements in large-scale data analysis. The book ends with a series of case studies examining potential applications of these technologies.

Acute Neuronal Injury

Автор: Denson G. Fujikawa
Название: Acute Neuronal Injury
ISBN: 3319774948 ISBN-13(EAN): 9783319774947
Издательство: Springer
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Цена: 13974.00 р.
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Описание: An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death.The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition.

Alterations in the Neuronal Cytoskeleton in Alzheimer Disease

Автор: George Perry
Название: Alterations in the Neuronal Cytoskeleton in Alzheimer Disease
ISBN: 1461289203 ISBN-13(EAN): 9781461289203
Издательство: Springer
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Цена: 13974.00 р.
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Описание: Although there is a general consensus that these abnormal filaments do contain cytoskeletal elements, much debate remains regarding which cytoskeletal elements are incorporated and whether the cytoskeletal rearrangement is primary or secondary to other cellular changes.

Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease

Автор: Francisco Gonzalez-Lima
Название: Cytochrome Oxidase in Neuronal Metabolism and Alzheimer`s Disease
ISBN: 1475799381 ISBN-13(EAN): 9781475799385
Издательство: Springer
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Цена: 32142.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Proceedings of an International Symposium held in New Orleans, Louisiana, October 28, 1997


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