Автор: Banga, Ajay K Название: Transdermal and Intradermal Delivery of Therapeutic Agents ISBN: 0367382784 ISBN-13(EAN): 9780367382780 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment. Advancements in science combined with the need for diverse drug delivery modalities have introduced a variety of transdermal and intradermal products for existing drugs at a fraction of the cost of new drug development. Commercialization of transdermal drug delivery requires technology from many disciplines beyond pharmaceutical sciences, such as polymer chemistry, adhesion sciences, mass transport, web film coating, printing, and medical technology.
A comprehensive discussion of these technologies and practices, Transdermal and Intradermal Delivery of Therapeutic Agents: Application of Physical Technologies covers:
Commercial development of devices and products based on transdermal physical enhancement technologies
Selecting optimal enhancement technology for a specific drug molecule using case studies
Physicochemical properties and practical commercial considerations related to cost, unmet clinical needs, marketing, or intellectual property protection
Technologies such as microneedles, iontophoresis, electroporation, and sonophoresis, with examples for delivery of small molecules, cosmeceuticals, proteins, and vaccines
Practical information on experimental procedures and challenges related to skin irritation and safety issues
Up-to-date and accessible to researchers and industry experts, this book provides a comprehensive discussion of the physical approaches and practical considerations for the laboratory and marketplace.
Название: Transdermal Drug Delivery Systems ISBN: 0367395703 ISBN-13(EAN): 9780367395704 Издательство: Taylor&Francis Рейтинг: Цена: 9798.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Brent E. Vecchia and Annette L. BungeSkin Absorption Databases and Predictive Equations Brent E. Vecchia and Annette L. BungePartitioning of Chemicals into Skin: Results and Predictions Brent E. Vecchia and Annette L. BungeIontophoresis: Applications in Drug Delivery and Noninvasive Monitoring M. Bego?a Delgado-Charro and Richard H. GuySkin Electroporation for Transdermal and Topical Drug Delivery V?ronique Pr?at and Rita VanbeverSonophoresis: Ultrasound-Enhanced Transdermal Drug Delivery Victor MeidanMetabolic Approach to Transdermal Drug Delivery Peter M. Elias, Kenneth R. Feingold, Janice Tsai, Carl Thornfeld, and Gopinathan Menon The Application of Supersaturated Systems to Percutaneous Drug Delivery Mark Pellett, S. Lakshmi Raghavan, Jonathan Hadgraft, and Adrian DavisMinimally Invasive Systems for Transdermal Drug Delivery James A. Down and Noel G. HarveyTransdermal Drug Delivery System Regulatory Issues Vinod P. ShahIndex
Автор: Jaspreet Singh Kochhar; Justin J. Y. Tan; Yee Chin Название: Microneedles for Transdermal Drug Delivery ISBN: 3030154432 ISBN-13(EAN): 9783030154431 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers. Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo . Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.
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