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Liver Fibrosis: Clinical Perspectives, Bush Finley


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Цена: 23335.00р.
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Автор: Bush Finley
Название:  Liver Fibrosis: Clinical Perspectives
ISBN: 9781632429568
Издательство: Foster Academics
Классификация:
ISBN-10: 163242956X
Обложка/Формат: Hardcover
Страницы: 248
Вес: 0.87 кг.
Дата издания: 15.09.2020
Язык: English
Размер: 27.99 x 21.59 x 1.60 cm
Читательская аудитория: General (us: trade)
Подзаголовок: Clinical perspectives
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Поставляется из: США
Описание: Liver fibrosis is a pathological condition of the liver that occurs due to chronic damage to the liver along with the accumulation of extracellular matrix proteins. These proteins act to form a fibrous scar. Such liver injury is caused due to chronic hepatitis C virus infection, non-alcoholic steatohepatitis (NASH) and alcohol abuse. Besides these, hepatitis B infection, primary sclerosis, primary biliary cirrhosis and cholangitis may also contribute to liver fibrosis. With time, as the liver becomes more scarred, a condition known as cirrhosis sets in. The progression of fibrosis is usually stealthy with minor symptoms, such as appetite loss, fluid buildup in legs or stomach, nausea, jaundice, etc. This progression from fibrosis to cirrhosis can take close to 15-20 years and is largely determined by both genetic and environmental factors. Various complications such as renal failure, ascites, hepatic encephalopathy and variceal bleeding may occur. It is usually detected at an advanced stage. The underlying cause of the fibrosis can be usually treated. Different antifibrotics may be prescribed to reduce scarring. In its advanced stage, the only treatment modality available is a liver transplantation. This book covers in detail the clinical perspectives in the pathophysiology and development of liver fibrosis. Different approaches, evaluations, methodologies and advanced studies on liver fibrosis and cirrhosis have been included herein. It is a collective contribution of a renowned group of international experts.


Liver Fibrosis: Pathophysiology, Diagnosis and Management

Автор: Bush Finley
Название: Liver Fibrosis: Pathophysiology, Diagnosis and Management
ISBN: 1632419106 ISBN-13(EAN): 9781632419101
Издательство: Неизвестно
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Цена: 22530.00 р.
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Описание: Liver fibrosis is a condition of the liver characterized by the excessive accumulation of extracellular matrix proteins such as collagen. Advanced liver fibrosis leads to cirrhosis of the liver. Cirrhosis leads to hepatocellular dysfunction and a high intrahepatic resistance to blood flow that results in hepatic insufficiency and portal hypertension. Liver biopsy is the standard procedure for diagnosing and assessing liver fibrosis. To determine the degree of liver damage, several scales such as Ishak fibrosis score (stages I-V) and METAVIR scoring system (stages I-IV) are used for staging of fibrosis. Other evaluations such as platelet count, ascites, Bonacini cirrhosis discriminant score and spider angiomata can help to diagnose cirrhosis. Recent evidence points to the reversibility of liver fibrosis even in its advanced stages. Typically, this may happen with a cessation of liver injury, via the successful treatment of the underlying disease. For patients with cirrhosis, liver transplantation is currently the only curative strategy with improved quality of life and better chances of survival. A lot of research is being undertaken to develop non-invasive and reliable markers of liver fibrosis, and liver specific antifibrotic therapies. This book aims to shed light on some of the unexplored aspects of liver fibrosis and the recent researches in this pathological condition. The objective of this book is to give a general view of the different aspects of its pathophysiology, diagnosis and management. This book, with its detailed analyses and data, will prove immensely beneficial to professionals and students involved in hepatology at various levels.

Liver Fibrosis: Symptoms, Mechanisms and Management

Автор: Bush Finley
Название: Liver Fibrosis: Symptoms, Mechanisms and Management
ISBN: 1632416395 ISBN-13(EAN): 9781632416391
Издательство: Неизвестно
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Цена: 24944.00 р.
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Diagnosis and Treatment of Liver Fibrosis

Автор: Bush Finley
Название: Diagnosis and Treatment of Liver Fibrosis
ISBN: 163242682X ISBN-13(EAN): 9781632426826
Издательство: Неизвестно
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Цена: 24944.00 р.
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