Описание: This book reviews current progress on heat shock proteins in the brain and their implications for neurodegenerative diseases, neuroprotection, aging and control of life span. It features contributions from laboratories from major universities around the world.
Автор: E.A. Neuwelt Название: Implications of the Blood-Brain Barrier and Its Manipulation ISBN: 1461280397 ISBN-13(EAN): 9781461280392 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Finally, the 1967 paper by Reese and Kamovsky, 11 entitled "Fine structural localization of a blood-brain barrier to exogenous peroxidase," sited the barrier at the continuous layer of cerebrovascular endothelial cells, which are connected by tight junctions.
Автор: E.A. Neuwelt Название: Implications of the Blood-Brain Barrier and Its Manipulation ISBN: 1461572576 ISBN-13(EAN): 9781461572572 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Future brain treatments with regulatory peptides, immune mediators, and gene components will require selective methods to deliver these agents to specific brain regions.
Описание: Neuroscience for Clinicians is a comprehensive and clinically relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms. By emphasizing how genetic, molecular, and cellular processes and their interactions control the function of the nervous system, the work will help clinicians understand emerging concepts about the mechanisms of neurologic disorders including neurodegeneration, channelopathies, and synaptic dysfunction that provide potential therapeutic targets . This single-authored textbook utilizes ample figures and tables throughout in order to facilitate retention of the core concepts presented. Divided into 5 sections, the first section includes chapters focused on basic cellular processes. Section 2 includes chapters focused on cell communication while Section 3 focuses on the neuronal microenvironment. The fourth section focuses on the organization and interactions of circuits in the cortex, thalamus, and brainstem, underlying behavioral states such as sleep, sensory processing, and motor control. The fifth section addresses mechanisms of pain and neural control of survival. And the final section covers concepts on mechanisms of emotion, social behavior, memory, language, and executive functions with emphasis on dementia and behavioral disorders.
Описание: In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important advances in translational research for stroke and other neurological diseases.
Описание: Interest in techniques to control the brain and thereby improve its function has surged, yet how realistic are these expectations and what are the ethical implications? This book reviews the main techniques of controlling brain processes for medical purposes, situating them within ethical and legal debates on autonomy and fairness.
Описание: This book provides an overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders.
Описание: Brain network function and dysfunction is the dominant model for understanding how the brain gives rise to normal and abnormal behavior.
Автор: Kato N., Kawata M., Pitman R. K. Название: Ptsd: Brain Mechanisms and Clinical Implications ISBN: 4431560874 ISBN-13(EAN): 9784431560876 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent catastrophic events, such as the attack on the New York World Trade Center and the devastating tsunami in the Indian Ocean, have drawn increasing attention to post-traumatic stress disorder, or PTSD. Once thought of only in psychological terms, PTSD has emerged as the model mental disorder for studying the effect of the environment on human biological systems, especially the brain. This book breaks new ground by offering neuroscientific insights into PTSD and their implications for diagnosis, prevention, and treatment. The recent explosion of biological investigation into this distressing and disabling condition has been led by this volume’s authors, who range from skilled basic scientists to experienced diagnosticians and therapists. Their contributions epitomize state-of-the-art, translational research in clinical neuroscience, and will prove to be an invaluable source of reference for practitioners and researchers in this field.
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