Описание: Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat autoimmune diseases, others have evolved from previous theories and ideas that have only now gained momentum and a deeper understanding such as the role of HLA or gender in MS susceptibility. This book covers these emerging and evolving topics and highlights the substantial advancements made in elucidation of the factors regulating susceptibility or disease progression, identification of new ways to monitor or predict MS pathology, and development of new strategies for treating MS.
Описание: Proceedings of a symposium held under the auspices of the Federation of European Microbiological Societies, at Ramat Rachel, Israel, May 15-19, 1989.
Автор: Erg?ven Название: Midkine: From Embryogenesis to Pathogenesis and Therapy ISBN: 9400799489 ISBN-13(EAN): 9789400799486 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book combines an extensive, up-to-date literature overview with reports on the lastest research about midkine. Its detailed format conveys the role of midkine as both a pathologic factor and a therapeutic agent.
Описание: Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment.
Название: Fungal Pathogenesis in Humans: The Growing Threat ISBN: 3038979007 ISBN-13(EAN): 9783038979005 Издательство: Неизвестно Рейтинг: Цена: 9409.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Dear Colleagues, Cancer survival rates and successful organ transplantation in patients continues to increase due to improvements in early diagnosis and treatments. Since immuno-suppressive therapies are frequently used, the mortality rate due to secondary infections has become an ever-increasing problem. Opportunistic fungal infections are probably the deadliest threat to these patients due to their difficult early diagnosis, the limited effect of antifungal drugs and the appearance of resistances. In recent years, a considerable effort has been devoted to investigating the role of many virulence traits in the pathogenic outcome of fungal infections. New virulence factors (hypoxia adaptation, CO2 sensing, pH regulation, micronutrient acquisition, secondary metabolites, immunity regulators, etc.) have been reported and their molecular mechanisms of action are being thoroughly investigated. The recent application of gene-editing technologies such as CRISPr-Cas9, has opened a whole new window to the discovery of new fungal virulence factors. Accurate fungal genotyping, Next Generation Sequencing and RNAseq approaches will undoubtedly provide new clues to interpret the plethora of molecular interactions controlling these complex systems. Unraveling their intimate regulatory details will provide insights for a more target-focused search or a rational design of more specific antifungal agents. This Special Issue is show significant discoveries, proofs of concept of new theories or relevant observations in fungal pathogenesis and its regulation. Dr. Fernando Leal Guest Editor
Описание: Yosemite is one of the most visited national parks, with scenery that is world-renowned. Photographer Harold Davis has explored Yosemite for years with his camera, finding the best vantage points and most photogenic times of year. Postcards in this book show Yosemite in winter, Vernal and Nevada Falls, Mirror Lake, Yosemite Valley, the view from Inspiration Point, and more
Автор: J.E. Vanderplank Название: Genetic and Molecular Basis of Plant Pathogenesis ISBN: 3642669670 ISBN-13(EAN): 9783642669675 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As befits a volume in the Advanced Series in Agricultural Sciences, this book was written with problems of practical agriculture in mind. Half the book could not have been written 20 years ago, even if there had then been available all the literature that has since accumulated on the genetics and chemistry of plant disease.
Автор: Mark P. Mattson Название: Pathogenesis of Neurodegenerative Disorders ISBN: 1617372153 ISBN-13(EAN): 9781617372155 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer`s, Parkinson`s, and Huntington`s diseases.
Автор: Wilson Brenda A. Название: Bacterial Pathogenesis: A Molecular Approach ISBN: 1555819400 ISBN-13(EAN): 9781555819408 Издательство: Wiley Рейтинг: Цена: 16782.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Revised and updated edition of the work originally authored by Abigail Salyers and Dixie Whitt.
Автор: Thomas P. Pirone; John G. Shaw Название: Viral Genes and Plant Pathogenesis ISBN: 1461280060 ISBN-13(EAN): 9781461280064 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Rolf C. Gaillard Название: The Acth Axis: Pathogenesis, Diagnosis and Treatment ISBN: 1461351081 ISBN-13(EAN): 9781461351085 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The student of Cushing`s Disease and the HPA axis will find elucidation of the latest basic scientific advances, coupled with patient friendly guidelines for clinical diagnosis and management of an extremely challenging neuroendocrine disorder.
YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer: A Critical Therapeutic Target describes, for the first time, the current state of the art of the transcription factor YY1, overexpressed in the majority of cancers and a central factor that regulates all of the major features and characteristics of human cancers. It provides compelling evidence of the novel potential therapeutic intervention by targeting YY1, which would result in the reversal of tumor cell properties and would propose YY1 as a novel prognostic/diagnostic biomarker for human cancers.
This book emphasizes the biochemical, molecular, and genetic underlying mechanisms by which YY1 regulates its pro-cancerous activities. In addition, it also describes the role of YY1 in the regulation of tumor cell resistance to conventional chemo and immunotherapies, the important role of inhibiting YY1 in cancer and proposes the development of new therapeutic drugs that inhibit YY1.The book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in understanding further the role of YY1 in cancer.
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