Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids.
This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.
Описание: A comprehensive reference on the synthetic chemistry of cycloaddition reactions Dipolar cycloaddion reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Such asymmetric syntheses have a growing importance in the pharmaceutical and agricultural industries with respect to the preparation of chiral drugs and natural products. This much-needed volume updates the popular 1984 edition with advances made over the last twenty years in cycloaddition reactions. While the 1984 volume focused on theory, structure, reactivities, and selectivities, the new volume is geared toward synthetic applications. Both carbonyl ylides and nitronates, important members of the 1,3-dipole family that were not reviewed previously, are now included. Also, beyond the capability of the 1,3-dipolar cycloadditon reaction to produce heterocycles, the ability of heteroatom-containing cycloadducts to transform into a variety of other functionalized organic molecules, cylclic or acyclic, and the ability of many 1,3-dipolar cycloadditions to generate rings containing several contiguous stereocenters in one synthetic operation is discussed. Volume 59 provides the only comprehensive reference on the market detailing the synthetic chemistry of cycloaddition reactions.
Автор: K. L. Ameta; Anshu Dandia Название: Green Chemistry: Synthesis of Bioactive Heterocycles ISBN: 8132218493 ISBN-13(EAN): 9788132218494 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc.
Late Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the author's expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.
Highlights the latest developments in the field in a concise volume
Provides details of key fluorinating reagents across diverse families of organic compounds
Explores the current applications and future potential of fluorine in drug development
A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles
Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research.
This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones.
Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications
Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids
Discusses how to synthesize rings of specific sizes
Covers sustainable synthetic approaches for obtaining salts
Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.
Автор: K. L. Ameta; Anshu Dandia Название: Green Chemistry: Synthesis of Bioactive Heterocycles ISBN: 8132229010 ISBN-13(EAN): 9788132229018 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc.
Автор: Romano V. A. Orru; Eelco Ruijter Название: Synthesis of Heterocycles via Multicomponent Reactions I ISBN: 3642263348 ISBN-13(EAN): 9783642263347 Издательство: Springer Рейтинг: Цена: 43100.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Banfi ГЇВїВЅ A. Basso ГЇВїВЅ R. Chebanov ГЇВїВЅ K. Gura ГЇВїВЅ S.M. Huang ГЇВїВЅ K. Khoury ГЇВїВЅ A. Elders ГЇВїВЅ E. Ruijter ГЇВїВЅ V.G. Nenajdenko ГЇВїВЅ R.V.A. Cukalovic ГЇВїВЅ J.-C.M.R. Monbaliu ГЇВїВЅ C.V. Wessjohann ГЇВїВЅ C.R.B. Rhoden ГЇВїВЅ D.G. Rivera ГЇВїВЅ O. del Mar Sanchez Duque ГЇВїВЅ C. Allais ГЇВїВЅ N. Isambert ГЇВїВЅ T. Constantieux ГЇВїВЅ J.
Автор: Ananya Srivastava; Chandan K. Jana Название: Heterocycles via Cross Dehydrogenative Coupling ISBN: 9811391467 ISBN-13(EAN): 9789811391460 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Поставка под заказ.
Описание: This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC).
Автор: Ananya Srivastava; Chandan K. Jana Название: Heterocycles via Cross Dehydrogenative Coupling ISBN: 9811391432 ISBN-13(EAN): 9789811391439 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Поставка под заказ.
Описание: This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles – an area that has attracted significant attention in both academic and industrial research.
Автор: Matthias D`hooghe; Hyun-Joon Ha Название: Synthesis of 4- to 7-membered Heterocycles by Ring Expansion ISBN: 3319249584 ISBN-13(EAN): 9783319249582 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community.
Автор: Ji Ram, Vishnu Название: The Chemistry of Heterocycles ISBN: 0081010338 ISBN-13(EAN): 9780081010334 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Heterocycles are ubiquitously present in nature and occupy a unique place in organic chemistry as they are part of the DNA and haemoglobin that make the life possible.
The Chemistry of HeterocyclesVolume 1 covers an introduction to the topic, followed by a chapter on the nomenclature of all classes of isolated, fused and polycyclic heterocycles. The third chapter delineates the highly strained three membered N, O and S containing aromatic and non-aromatic heterocycles with one and more than one similar and dissimilar heteroatom. The four-membered heterocycles are abundantly present in various natural and synthetic products of pharmacological importance. This chapter describes the natural abundance, synthesis, chemical reactivity, structural features and their medicinal importance. This class of compounds are present as sub-structures in penicillin and cytotoxic Taxol. Lastly, a chapter on the natural abundance, synthesis, chemical reactivity and pharmacological importance of 5-membered heterocycles with N, O, S heteroatom is covered. The chemistry of heterocycles with mixed heteroatom such as, N-S, N-O, N-S etc. is also described.
Gives in-depth, clear information about various systems of nomenclature along with widely acceptable IUPAC system for naming various classes of heterocycles
Provides complete information about natural occurrences, synthesis, chemical reactivity, pharmacological importance of heterocycles and their application in material science
Highly relevant for graduate students and researchers, providing updated information about various isolated and fused N, O and, S containing heterocycles
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