Genetics of Melanoma, Torres-Cabala Carlos A., Curry Jonathan L.
Автор: Lynn B. Jorde, John C. Carey , Michael J. Bamshad Название: Medical Genetics, 6 ed. ISBN: 0323597378 ISBN-13(EAN): 9780323597371 Издательство: Elsevier Science Рейтинг: Цена: 8757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Up to date and extensively revised to reflect recent advances in the genetics of common diseases, as well as current progress in gene therapy, Medical Genetics, 6th Edition, delivers easy-to-read, highly visual coverage of this rapidly changing field. This accessible, practical text integrates key concepts with clinical practice, highlighted by numerous illustrations, tables, concept summaries, and more - all designed to enhance effective learning and retention of complex material.
Discusses current topics
including polygenic risk scores and their potential applications for diabetes, cancer, and heart disease, and the latest sequencing technologies and their clinical application in genetic testing and diagnosis.
Offers a completely updated discussion of genetic testing modalities and applications.
Includes convenient concept summaries, more than 230 photographs, illustrations, and tables, as well as patient/family vignettes that present valuable perspectives on disease and treatment.
Features Clinical Commentary boxes that demonstrate how the hard science of genetics has real applications to everyday patient problems, preparing you for problem-based integrated courses.
Illustrates key concepts with disease examples to demonstrate relevance to medicine.
Provides study questions for self-assessment, as well as 200 additional USMLE-style questions online.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Автор: Eberhard Passarge Название: Color Atlas of Genetics, 5 еd. ISBN: 3132414409 ISBN-13(EAN): 9783132414402 Издательство: Thieme Verlagsgruppe Рейтинг: Цена: 10734.00 р. Наличие на складе: Нет в наличии.
Описание:
Ever since the International Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome, represented by approximately 3 billion base pairs, with its far-reaching implications for understanding the causes of human genetic disorders and their diagnosis, progress in the field has not slowed down.
In the fifth edition of the bestselling Color Atlas of Genetics, readers will be rewarded with a complete and current overview of the field, with an emphasis on the interface between fundamental principles and practical applications in medicine and the role of signaling pathways in causing diseases.
Using the acclaimed Flexibook format designed for easy visual learning and retention, the atlas is invaluable for students, clinicians, and scientists interested in staying up to date in this fast-evolving area.
New fully illustrated topics in the revised fifth edition of the atlas include:
An overview of disorders resulting from structural changes of the genome (genomic disorders)
Abnormal imprinting patterns
Examples of impaired signal pathways (laminopathies, fibrillinopathies, cohesinopathies, and others)
The CRISPR-Cas system
Genetic features of the aging processes
Disorders due to rearrangements of chromatin in the cell nucleus, and others
With almost 200 stunning color plates explained by concise texts on the opposite pages, including tables presenting useful data, a glossary of terms, key references, and online resources, the atlas presents clear and accessible concepts. It is an excellent refresher for investigators in any field of medicine or biology.
Автор: Peter D Turnpenny, Sian Ellard, Ruth Cleaver Название: Emery`s Elements of Medical Genetics and Genomics, 16e ISBN: 0702079669 ISBN-13(EAN): 9780702079665 Издательство: Elsevier Science Рейтинг: Цена: 7241.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Long recognized as a leading textbook in this fast-moving field, Emery's Elements of Medical Genetics and Genomics offers current, complete information with a strong basis in practical clinical genetics and genomics for medical school and beyond. The 16th Edition of this award-winning text has been thoroughly updated throughout and includes case-based and multiple-choice questions, end-of-chapter summaries, an extensive glossary, and convenient online access, making it an ideal choice for all medical undergraduates as well as postgraduates seeking to improve their understanding and knowledge.
Includes new case-based studies with questions and answers throughout, in addition to multiple-choice self-assessment questions for study and review.
Covers key topics such as pharmacogenetics, personalized medicine, prenatal testing, reproductive genetics, and ethical and legal issues in medical genetics.
Divides the text into three easy-to-use sections: The Scientific Basis of Human Genetics, Genetics in Medicine and Genomic Medicine, and Clinical Genetics, Counseling and Ethics
Features full-color illustrations and other images that help readers visualize the appearance of genetic disorders and assist with the understanding of complex genetic structures.
Contains learning features such as summary boxes, an extensive glossary of terms, online hyperlinks to important genetics websites and clinical databases, and more.
Presents the extensive knowledge and experience of distinguished editors Peter D. Turnpenny and Sian Ellard, as well as new editor Ruth Cleaver.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Автор: Giulio Costanzi Название: Clinical Management of Malignant Melanoma ISBN: 089838656X ISBN-13(EAN): 9780898386561 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco- logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi- nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev- er be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by div- iding the oncology literature into specific subdividions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Автор: Ralph A. Reisfeld; Soldano Ferrone Название: Melanoma Antigens and Antibodies ISBN: 1468440810 ISBN-13(EAN): 9781468440812 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Melanoma is an aggressive type of cancer for which treatment has dramatically evolved during the last 15 years, improving response and survival figures. This book, written by a diverse panel of experts, presents a description of the most relevant aspects of the epidemiology, diagnosis, local treatment, prognostic biomarkers and treatment for advanced disease, including the most recent research on novel molecules that are either approved or are undergoing clinical development. It includes insights on such challenging topics as when immunotherapy should be started in BRAF mutant patients, or which is the most appropriate treatment algorithm in those cases, as well as how to handle difficult and poor-prognosis melanoma cases, such as patients with brain metastases or patients with the uveal disease.
Автор: Larry Nathanson Название: Basic and Clinical Aspects of Malignant Melanoma ISBN: 0898388562 ISBN-13(EAN): 9780898388565 Издательство: Springer Рейтинг: Цена: 30606.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdividions such as lung cancer, genitouri- nary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Автор: Nash Frederick Название: Treatment and Management of Melanoma ISBN: 1632424088 ISBN-13(EAN): 9781632424082 Издательство: Неизвестно Цена: 23979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Schadendorf Название: Handbook of Cutaneous Melanoma ISBN: 1908517972 ISBN-13(EAN): 9781908517975 Издательство: Springer Рейтинг: Цена: 6008.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This review of current treatment guidelines for local and metastatic cutaneous melanoma offers advice based on recent clinical trials, backed by illustrations and treatment algorithms. It covers everything from epidemiology to pathogenesis and staging.
Автор: Thurin Название: Molecular Diagnostics for Melanoma ISBN: 1627037268 ISBN-13(EAN): 9781627037266 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the diagnostics of melanoma. It features step-by-step, readily reproducible laboratory protocols.
Автор: Ryan J. Sullivan Название: BRAF Targets in Melanoma ISBN: 1493921428 ISBN-13(EAN): 9781493921423 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF inhibitors are effective for a short period of time, but there is little hope that this drugs as single agents will lead to durable benefit in a majority of patients. Among scientists and researchers who work in drug discovery, there is a lot of interest in the development of molecularly targeted cancer agents. Namely, the identification of a molecular target, the selection of molecules which effectively inhibit this target. What is starkly different about the development of this class of compounds, however, is that the mechanism of action of these agents are not as straightforward as was once previously assumed and the mechanisms of resistance that tumor cells employ to evade complete destruction are unlike any that have been described before. These discoveries in addition to utilization of modern molecular biology techniques have led to a series of hypotheses regarding which other types of molecules could be used in combination with BRAF-inhibitors in hopes of revolutionizing the potential of therapeutics in melanoma.
Автор: Howard L. Kaufman; Janice M. Mehnert Название: Melanoma ISBN: 3319225383 ISBN-13(EAN): 9783319225388 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Heterogeneity in Melanoma.- Melanoma Epidemiology and Prevention.- Methods Of Melanoma Detection.- Melanoma: Clinical Presentations.- Principles Of Melanoma Stagin.- Surgical Management of Melanoma.- Adjuvant Therapy of Melanoma.- Chemotherapy for Melanoma.- Checkpoint Blockade for the Treatment of Advanced Melanoma.- Targeted Therapy for Melanoma.- Treatment of Melanoma CNS Metastases.- Treatment of Melanoma CNS Metastases.- Mucosal Melanoma: Epidemiology, Biology and Treatment.- Acral Lentiginous Melanoma.- Pediatric Melanoma and Atypical Melanocytic Neoplasms.- Novel Treatments in Development for Melanoma.
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